EC - Glucose-6-phosphate dehydrogenase (coenzyme-F420)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
glucose-6-phosphate dehydrogenase (coenzyme-F420)
Other names:
coenzyme F420-dependent glucose-6-phosphate dehydrogenase
F420-dependent glucose-6-phosphate dehydrogenase
F420-dependent glucose-6-phosphate dehydrogenase 1
Systematic name:
D-glucose-6-phosphate:F420 1-oxidoreductase



The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, flavin adenine dinucleotide and flavin mononucleotide [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052749
UniProtKB/Swiss-Prot: (23) [show] [UniProt]


  1. Purwantini, E., Daniels, L.
    Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.
    J. Bacteriol. 178: 2861-2866 (1996). [PMID: 8631674]
  2. Bashiri, G., Squire, C. J., Baker, E. N., Moreland, N. J.
    Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system.
    Protein Expr. Purif. 54: 38-44 (2007). [PMID: 17376702]
  3. Purwantini, E., Gillis, T. P., Daniels, L.
    Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.
    FEMS Microbiol. Lett. 146: 129-134 (1997). [PMID: 8997717]

[EC created 2010 as EC, transferred 2011 to EC]