EC 1.1.5.7 - Cyclic alcohol dehydrogenase (quinone)

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IntEnz Enzyme Nomenclature
EC 1.1.5.7

Names

Accepted name:
cyclic alcohol dehydrogenase (quinone)
Other names:
cyclic alcohol dehydrogenase
MCAD
Systematic name:
cyclic alcohol:quinone oxidoreductase

Reaction

Comments:

This enzyme oxidizes a wide variety of cyclic alcohols. Some minor enzyme activity is found with aliphatic secondary alcohols and sugar alcohols, but not primary alcohols. The enzyme is unable to catalyse the reverse reaction of cyclic ketones or aldehydes to cyclic alcohols. This enzyme differs from EC 1.1.5.5, alcohol dehydrogenase (quinone), which shows activity with ethanol [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Moonmangmee, D., Fujii, Y., Toyama, H., Theeragool, G., Lotong, N., Matsushita, K., Adachi, O.
    Purification and characterization of membrane-bound quinoprotein cyclic alcohol dehydrogenase from Gluconobacter frateurii CHM 9.
    Biosci. Biotechnol. Biochem. 65: 2763-2772 (2001). [PMID: 11826975]

[EC 1.1.5.7 created 2010]