EC 220.127.116.11 - (S)-2-hydroxyglutarate dehydrogenase
IntEnz Enzyme Nomenclature
- (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol
The enzyme, characterized from the bacterium Escherichia coli, contains an FAD cofactor that is not covalently attached. It is bound to the cytoplasmic membrane and is coupled to the membrane quinone pool.
Links to other databases
Identification of Escherichia coli YgaF as an L-2-hydroxyglutarate oxidase.J. Bacteriol. 190 : 3793-3798 (2008). [PMID: 18390652]
Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.Nat Commun 9 : 5071 (2018). [PMID: 30498244]
[EC 18.104.22.168 created 2019]