EC - D-mannitol oxidase

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IntEnz Enzyme Nomenclature


Accepted name:
D-mannitol oxidase
Other names:
D-arabitol oxidase
mannitol oxidase
D-arabinitol oxidase
Systematic name:
mannitol:oxygen oxidoreductase (cyclizing)



Also catalyses the oxidation of D-arabinitol and, to a lesser extent, D-glucitol (sorbitol), whereas L-arabinitol is not a good substrate. The enzyme from the snails Helix aspersa and Arion ater is found in a specialised tubular organelle that has been termed the mannosome.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050581


  1. Vorhaben, J.E., Scott, J.F., Smith, D.D. and Campbell, J.W.
    Mannitol oxidase: partial purification and characterisation of the membrane-bound enzyme from the snail Helix aspersa.
    Int. J. Biochem. 18: 337-344 (1986). [PMID: 3519307]
  2. Large, A.T., Jones, C.J.P. and Connock, M.J.
    The association of mannitol oxidase with a distinct organelle in the digestive gland of the terrestrial slug Arion ater.
    Protoplasma 175: 93-101 (1993).

[EC created 2001]