EC - D-lactate dehydrogenase (cytochrome)

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IntEnz Enzyme Nomenclature


Accepted name:
D-lactate dehydrogenase (cytochrome)
Other names:
D-(-)-lactic cytochrome c reductase
D-lactate (cytochrome) dehydrogenase
D-lactate-cytochrome c reductase
cytochrome-dependent D-(-)-lactate dehydrogenase
lactic acid dehydrogenase
Systematic name:
(R)-lactate:ferricytochrome-c 2-oxidoreductase




A flavoprotein (FAD).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004458
CAS Registry Number: 37250-79-6


  1. Gregolin, C. and Singer, T.P.
    The lactate dehydrogenase of yeast. III. D-(-)-Lactate cytochrome c reductase, a zinc-flavoprotein from aerobic yeast.
    Biochim. Biophys. Acta 67: 201-218 (1963). [PMID: 13950255]
  2. Gregolin, C., Singer, T.P., Kearney, E.B. and Boeri, E.
    The formation and enzymatic properties of the various lactic dehydrogenases of yeast.
    Ann. N.Y. Acad. Sci. 94: 780-797 (1961). [PMID: 13901630]
  3. Nygaard, A.P.
    D(-)-Lactate cytochrome c reductase, a flavoprotein from yeast.
    J. Biol. Chem. 236: 920-925 (1961). [PMID: 13729965]
  4. Nygaard, A.P.
    Lactate dehydrogenases of yeast.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 7, Academic Press, New York, 1963, 557-565

[EC created 1961]