EC 1.1.2.3 - L-lactate dehydrogenase (cytochrome)

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IntEnz Enzyme Nomenclature
EC 1.1.2.3

Names

Accepted name:
L-lactate dehydrogenase (cytochrome)
Other names:
L(+)-lactate:cytochrome c oxidoreductase
L-lactate cytochrome c oxidoreductase
L-lactate cytochrome c reductase
cytochrome b2 (flavin-free derivative of flavocytochrome b2)
dehydrogenase, lactate (cytochrome)
flavocytochrome b2
lactate dehydrogenase (cytochrome)
lactic acid dehydrogenase
lactic cytochrome c reductase
L-lactate ferricytochrome c oxidoreductase
Systematic name:
(S)-lactate:ferricytochrome-c 2-oxidoreductase

Reaction

Cofactors

Comments:

Identical with cytochrome b2; a flavohemoprotein (FMN).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00170 , PROSITE:PDOC00482
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004460
CAS Registry Number: 9078-32-4
UniProtKB/Swiss-Prot:

References

  1. Appleby, C.A. and Morton, R.K.
    Lactic dehydrogenase and cytochrome b2 of baker's yeast. Purification and crystallization.
    Biochem. J. 71: 492-499 (1959). [PMID: 13638255]
  2. Appleby, C.A. and Morton, R.K.
    Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme.
    Biochem. J. 73: 539-550 (1959). [PMID: 13793977]
  3. Bach, S.G., Dixon, M. and Zerfas, L.G.
    Yeast lactic dehydrogenase and cytochrome b2.
    Biochem. J. 40: 229-239 (1946). [PMID: 16747991]
  4. Nygaard, A.P.
    Lactate dehydrogenases of yeast.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 7, Academic Press, New York, 1963, 557-565

[EC 1.1.2.3 created 1961]