EC 1.1.1.n11 - Succinic semialdehyde reductase

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IntEnz Enzyme Nomenclature
EC 1.1.1.n11

This is a preliminary EC number. The content has not yet been validated and included in the official IUBMB Enzyme list.


Accepted name:
succinic semialdehyde reductase
Other name:
Systematic name:
4-hydroxybutanoate:NADP+ oxidoreductase


Links to other databases

Enzymes and pathways: ENZYME@ExPASy


  1. Cash, C. D., Maitre, M., Mandel, P.
    Purification from human brain and some properties of two NADPH-linked aldehyde reductases which reduce succinic semialdehyde to 4-hydroxybutyrate.
    J. Neurochem. 33 : 1169-1175 (1979). [PMID: 45199]
  2. Zhu, X., Lapthorn, A. J., Ellis, E. M.
    Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.
    Biochemistry 45 : 1562-1570 (2006). [PMID: 16460003]

[EC 1.1.1.n11 created 2010]