EC - D-xylulose reductase

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IntEnz Enzyme Nomenclature


Accepted name:
D-xylulose reductase
Other names:
2,3-cis-polyol(DPN) dehydrogenase (C3-5)
NAD-dependent xylitol dehydrogenase
erythritol dehydrogenase
pentitol-DPN dehydrogenase
xylitol dehydrogenase
Systematic name:
xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)



Also acts as an L-erythrulose reductase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00058
Structural data: CSA , EC2PDB
Gene Ontology: GO:0046526
CAS Registry Number: 9028-16-4
UniProtKB/Swiss-Prot: (17) [show] [UniProt]


  1. Chiang, C. and Knight, S.G.
    A new pathway of pentose metabolism.
    Biochem. Biophys. Res. Commun. 3: 554-559 (1960).
  2. Hickman, J. and Ashwell, G.
    A sensitive and stereospecific enzymatic assay for xylulose.
    J. Biol. Chem. 234: 758-761 (1959).
  3. Jakoby, W.B. and Fredericks, J.
    Erythritol dehydrogenase from Aerobacter aerogenes.
    Biochim. Biophys. Acta 48: 26-32 (1961).

[EC created 1961]