EC - Glyoxylate reductase (NADP+)

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IntEnz Enzyme Nomenclature


Accepted name:
glyoxylate reductase (NADP+)
Other name:
NADPH-glyoxylate reductase
Systematic name:
glycolate:NADP+ oxidoreductase



Also reduces hydroxypyruvate to glycerate; has some affinity for NAD+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030267
CAS Registry Number: 37250-17-2
UniProtKB/Swiss-Prot: (121) [show] [UniProt]


  1. Cartwright, L.N. and Hullin, R.P.
    Purification and properties of two glyoxylate reductases from a species of Pseudomonas.
    Biochem. J. 101 : 781-791 (1966).
  2. Kleczkowski, L.A., Randall, D.D. and Blevins, D.G.
    Purification and characterization of a novel NADPH(NADH)-dependent glyoxylate reductase from spinach leaves. Comparison of immunological properties of leaf glyoxylate reductase and hydroxypyruvate reductase.
    Biochem. J. 239 : 653-659 (1986). [PMID: 3548703]

[EC created 1972]