IntEnz

EC 1.1.1.79 - Glyoxylate reductase (NADP⁺)

IntEnz Enzyme Nomenclature
EC 1.1.1.79

Names

Reaction

• 10992 [IUBMB]
  glycolate

  glycolate

  Name origin: UniProt - CHECKED (C)

  CHEBI:29805

  Formula: C2H3O3
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  NADP⁺

  NADP(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:58349

  Formula: C21H25N7O17P3
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  =

  glyoxylate

  glyoxylate

  Name origin: UniProt - CHECKED (C)

  CHEBI:36655

  Formula: C2HO3
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  NADPH

  NADPH

  Name origin: UniProt - CHECKED (C)

  CHEBI:57783

  Formula: C21H26N7O17P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

Comments:

Also reduces hydroxypyruvate to glycerate; has some affinity for NAD⁺.

Links to other databases

References

1. Cartwright, L.N. and Hullin, R.P.
   Purification and properties of two glyoxylate reductases from a species of Pseudomonas.
   Biochem. J. 101: 781-791 (1966).
2. Kleczkowski, L.A., Randall, D.D. and Blevins, D.G.
   Purification and characterization of a novel NADPH(NADH)-dependent glyoxylate reductase from spinach leaves. Comparison of immunological properties of leaf glyoxylate reductase and hydroxypyruvate reductase.
   Biochem. J. 239: 653-659 (1986). [PMID: 3548703]

[EC 1.1.1.79 created 1972]