EC - Alcohol dehydrogenase [NAD(P)+]

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IntEnz Enzyme Nomenclature


Accepted name:
alcohol dehydrogenase [NAD(P)+]
Other names:
aldehyde reductase (NADPH/NADH)
retinal reductase
Systematic name:
alcohol:NAD(P)+ oxidoreductase



Reduces aliphatic aldehydes of carbon chain length from 2 to 14, with greatest activity on C4, C6 and C8 aldehydes; also reduces retinal to retinol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018455
CAS Registry Number: 37250-10-5


  1. Fidge, N.H. and Goodman, D.S.
    The enzymatic reduction of retinal to retinol in rat intestine.
    J. Biol. Chem. 243 : 4372-4379 (1968). [PMID: 4300551]

[EC created 1972]