IntEnz - EC 1.1.1.65

EC 1 - Oxidoreductases

EC 1.1 - Acting on the CH-OH group of donors

EC 1.1.1 - With NAD⁺ or NADP⁺ as acceptor

EC 1.1.1.65 - Pyridoxine 4-dehydrogenase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.1.1.65

Names

Accepted name:

pyridoxine 4-dehydrogenase

Other names:

pyridoxin dehydrogenase
pyridoxine dehydrogenase
pyridoxol dehydrogenase

Systematic name:

pyridoxine:NADP⁺ 4-oxidoreductase

Reaction

16129 [IUBMB]

NADP⁺

NADP(+)

Name origin: UniProt - CHECKED (C)

CHEBI:58349

Formula: C21H25N7O17P3
Charge: -3

ChEBI compound status: CHECKED (C)

+

pyridoxine

pyridoxine

Name origin: UniProt - CHECKED (C)

CHEBI:16709

Formula: C8H11NO3
Charge: 0

ChEBI compound status: CHECKED (C)

=

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

NADPH

NADPH

Name origin: UniProt - CHECKED (C)

CHEBI:57783

Formula: C21H26N7O17P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

pyridoxal

pyridoxal

Name origin: UniProt - CHECKED (C)

CHEBI:17310

Formula: C8H9NO3
Charge: 0

ChEBI compound status: CHECKED (C)

Comments:

Also oxidizes pyridoxine phosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0050236

CAS Registry Number: 9028-64-2

UniProtKB/Swiss-Prot:

PDXI_ECOLI

PLR1_ARATH

PLR1_SCHPO

PLR1_YEAST

PLR2_SCHPO

References

Holzer, H. and Schneider, S.

Reinigung und Charakterisierung einer TPN-abhängigen Pyridoxol-dehydrogenase aus Bierhefe.

Biochim. Biophys. Acta 48: 71-76 (1961).

[EC 1.1.1.65 created 1965, modified 1976]