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EC 1.1.1.407 - D-altritol 5-dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.407

Names

Accepted name:

D-altritol 5-dehydrogenase

Systematic name:

D-altritol:NAD⁺ 5-oxidoreductase

Reaction

51708 [IUBMB]

D-altritol

D-altritol

Name origin: UniProt - CHECKED (C)

CHEBI:134311

Formula: C6H14O6
Charge: 0

ChEBI compound status: CHECKED (C)

+

NAD⁺

NAD(+)

Name origin: UniProt - CHECKED (C)

CHEBI:57540

Formula: C21H26N7O14P2
Charge: -1

ChEBI compound status: CHECKED (C)

=

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

keto-D-tagatose

keto-D-tagatose

Name origin: UniProt - CHECKED (C)

CHEBI:47693

Formula: C6H12O6
Charge: 0

ChEBI compound status: CHECKED (C)

+

NADH

NADH

Name origin: UniProt - CHECKED (C)

CHEBI:57945

Formula: C21H27N7O14P2
Charge: -2

ChEBI compound status: CHECKED (C)

Comments:

The enzyme, characterized in Agrobacterium fabrum C58, also has low activity with D-mannitol and D-arabitol. It is part of a D-altritol degradation pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

UniProtKB/Swiss-Prot:

A9CES3

ATRDH_AGRFC

References

Wichelecki, D. J., Vetting, M. W., Chou, L., Al-Obaidi, N., Bouvier, J. T., Almo, S. C., Gerlt, J. A.

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel D-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.

J. Biol. Chem. 290: 28963-28976 (2015). [PMID: 26472925]

[EC 1.1.1.407 created 2017]

EC 1 - Oxidoreductases