EC - D-erythritol 1-phosphate dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
D-erythritol 1-phosphate dehydrogenase
Other name:
eryB (gene name)
Systematic name:
D-erythritol-1-phosphate 2-oxidoreductase



The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Sperry, J. F., Robertson, D. C.
    Erythritol catabolism by Brucella abortus.
    J. Bacteriol. 121: 619-630 (1975). [PMID: 163226]
  2. Sangari, F. J., Aguero, J., Garcia-Lobo, J. M.
    The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.
    Microbiology 146: 487-495 (2000). [PMID: 10708387]
  3. Barbier, T., Collard, F., Zuniga-Ripa, A., Moriyon, I., Godard, T., Becker, J., Wittmann, C., Van Schaftingen, E., Letesson, J. J.
    Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.
    Proc. Natl. Acad. Sci. U.S.A. 111: 17815-17820 (2014). [PMID: 25453104]

[EC created 2016]