EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.396 - Bacteriochlorophyllide-a dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.396
Names
Accepted name:
bacteriochlorophyllide-a dehydrogenase
Other
name:
bchC (gene name)
Systematic name:
3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide-a:NAD+ oxidoreductase (bacteriochlorophyllide a-forming)
Reactions
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48764 [IUBMB]3-devinyl-3-(1-hydroxyethyl)chlorophyllide aName origin: UniProt - CHECKED (C)Formula: C35H34MgN4O6
Charge: -2ChEBI compound status: CHECKED (C)NAD+Name origin: UniProt - CHECKED (C)Formula: C21H26N7O14P2
Charge: -1ChEBI compound status: CHECKED (C)=3-acetyl-3-devinylchlorophyllide aName origin: UniProt - CHECKED (C)Formula: C35H32MgN4O6
Charge: -2ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C) -
19733 [IUBMB]3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide aName origin: UniProt - CHECKED (C)Formula: C35H36MgN4O6
Charge: -2ChEBI compound status: CHECKED (C)NAD+Name origin: UniProt - CHECKED (C)Formula: C21H26N7O14P2
Charge: -1ChEBI compound status: CHECKED (C)=bacteriochlorophyllide aName origin: UniProt - CHECKED (C)Formula: C35H34MgN4O6
Charge: -2ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
The enzyme, together with EC 1.3.7.15, chlorophyllide-a reductase, and EC 4.2.1.165, chlorophyllide-a 31-hydratase, is involved in the conversion of chlorophyllide a to bacteriochlorophyllide a. The enzymes can act in multiple orders, resulting in the formation of different intermediates, but the final product of the cumulative action of the three enzymes is always bacteriochlorophyllide a. The enzyme oxidizes a hydroxyl group on ring A, converting it to an oxo group.
Links to other databases
References
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Promoter mapping and nucleotide sequence of the bchC bacteriochlorophyll biosynthesis gene from Rhodobacter capsulatus.Gene 83 : 251-261 (1989). [PMID: 2555268]
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Genetic analysis of the bchC and bchA genes of Rhodobacter sphaeroides.Mol. Gen. Genet. 236 : 227-234 (1993). [PMID: 8437569]
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Broadened Substrate Specificity of 3-Hydroxyethyl Bacteriochlorophyllide a Dehydrogenase (BchC) Indicates a New Route for the Biosynthesis of Bacteriochlorophyll a.J. Biol. Chem. 290 : 19697-19709 (2015). [PMID: 26088139]
[EC 1.1.1.396 created 2016]