EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)

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IntEnz Enzyme Nomenclature
EC 1.1.1.387

Names

Accepted name:
L-serine 3-dehydrogenase (NAD+)
Other name:
NAD+-dependent L-serine dehydrogenase
Systematic name:
L-serine:NAD+ 3-oxidoreductase

Reactions

Comments:

The enzyme, purified from the bacterium Pseudomonas aeruginosa, also shows activity with L-threonine (cf. EC 1.1.1.103, L-threonine 3-dehydrogenase). The enzyme has only very low activity with NADP+ [cf. EC 1.1.1.276, serine 3-dehydrogenase (NADP+)].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Tchigvintsev, A., Singer, A., Brown, G., Flick, R., Evdokimova, E., Tan, K., Gonzalez, C. F., Savchenko, A., Yakunin, A. F.
    Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
    J. Biol. Chem. 287 : 1874-1883 (2012). [PMID: 22128181]

[EC 1.1.1.387 created 2015]