EC - Acetoacetyl-CoA reductase

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IntEnz Enzyme Nomenclature


Accepted name:
acetoacetyl-CoA reductase
Other names:
(R)-3-hydroxyacyl-CoA dehydrogenase
β-ketoacyl-CoA reductase
D(-)-β-hydroxybutyryl CoA-NADP oxidoreductase
D-3-hydroxyacyl-CoA reductase
NADP-linked acetoacetyl CoA reductase
NADPH:acetoacetyl-CoA reductase
acetoacetyl coenzyme A reductase
hydroxyacyl coenzyme-A dehydrogenase
short chain β-ketoacetyl(acetoacetyl)-CoA reductase
Systematic name:
(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Protein domains and families: PROSITE:PDOC00060
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018454
CAS Registry Number: 9028-41-5


  1. Wakil, S.J. and Bressler, R.
    Studies on the mechanism of fatty acid synthesis. X. Reduced triphosphopyridine nucleotide-acetoacetyl coenzyme A reductase.
    J. Biol. Chem. 237 : 687-693 (1962).

[EC created 1961]