EC 1.1.1.355 - 2'-dehydrokanamycin reductase

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IntEnz Enzyme Nomenclature
EC 1.1.1.355

Names

Accepted name:
2'-dehydrokanamycin reductase
Other name:
kanK (gene name, ambiguous)
Systematic name:
kanamycin A:NADP+ oxidoreductase

Reaction

Comments:

Found in the bacterium Streptomyces kanamyceticus where it is involved in the conversion of kanamycin B to kanamycin A.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Sucipto, H., Kudo, F., Eguchi, T.
    The last step of kanamycin biosynthesis: unique deamination reaction catalyzed by the α-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK.
    Angew. Chem. Int. Ed. Engl. 51 : 3428-3431 (2012). [PMID: 22374809]

[EC 1.1.1.355 created 2013]