EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.354 - Farnesol dehydrogenase (NAD+)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.354
Names
Accepted name:
farnesol dehydrogenase (NAD+)
Other
name:
NAD+-farnesol dehydrogenase
Systematic name:
(2E,6E)-farnesol:NAD+ 1-oxidoreductase
Reaction
- (2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+
Comments:
The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. 1.1.1.347, geraniol dehydrogenase (NAD+)]. Unlike EC 1.1.1.216, farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.
Links to other databases
UniProtKB/Swiss-Prot:
GEDH_CARLC
References
-
Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae).FEBS J. 275 : 2807-2817 (2008). [PMID: 18422649]
[EC 1.1.1.354 created 2013]