EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.350 - Ureidoglycolate dehydrogenase (NAD+)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.350
Names
Accepted name:
ureidoglycolate dehydrogenase (NAD+)
Systematic name:
(S)-ureidoglycolate:NAD+ oxidoreductase
Reaction
- (S)-ureidoglycolate + NAD+ = N-carbamoyl-2-oxoglycine + NADH + H+
Comments:
Involved in catabolism of purines. The enzyme from the bacterium Escherichia coli is specific for NAD+ [2]. cf. EC 1.1.1.154, ureidoglycolate dehydrogenase [NAD(P)+].
Links to other databases
Enzymes and pathways:
NC-IUBMB
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BRENDA
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DIAGRAM
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ExplorEnz
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ENZYME@ExPASy
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KEGG
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MetaCyc
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UniPathway
UniProtKB/Swiss-Prot:
References
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Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.J. Bacteriol. 181 : 7479-7484 (1999). [PMID: 10601204]
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Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.PLoS ONE 7 : e52066 (2012). [PMID: 23284870]
[EC 1.1.1.350 created 2013]