EC - Ureidoglycolate dehydrogenase (NAD+)

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IntEnz Enzyme Nomenclature


Accepted name:
ureidoglycolate dehydrogenase (NAD+)
Systematic name:
(S)-ureidoglycolate:NAD+ oxidoreductase



Involved in catabolism of purines. The enzyme from the bacterium Escherichia coli is specific for NAD+ [2]. cf. EC, ureidoglycolate dehydrogenase [NAD(P)+].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Cusa, E., Obradors, N., Baldoma, L., Badia, J., Aguilar, J.
    Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
    J. Bacteriol. 181 : 7479-7484 (1999). [PMID: 10601204]
  2. Kim, M. I., Shin, I., Cho, S., Lee, J., Rhee, S.
    Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
    PLoS ONE 7 : e52066 (2012). [PMID: 23284870]

[EC created 2013]