IntEnz - EC 1.1.1.28

EC 1 - Oxidoreductases

EC 1.1 - Acting on the CH-OH group of donors

EC 1.1.1 - With NAD⁺ or NADP⁺ as acceptor

EC 1.1.1.28 - D-lactate dehydrogenase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.1.1.28

Names

Accepted name:

D-lactate dehydrogenase

Other names:

D-(-)-lactate dehydrogenase (NAD)
D-lactic acid dehydrogenase
D-lactic dehydrogenase
D-specific lactic dehydrogenase
lactic acid dehydrogenase

Systematic name:

(R)-lactate:NAD⁺ oxidoreductase

Reaction

16369 [IUBMB]

(R)-lactate

(R)-lactate

Name origin: UniProt - CHECKED (C)

CHEBI:16004

Formula: C3H5O3
Charge: -1

ChEBI compound status: CHECKED (C)

+

NAD⁺

NAD(+)

Name origin: UniProt - CHECKED (C)

CHEBI:57540

Formula: C21H26N7O14P2
Charge: -1

ChEBI compound status: CHECKED (C)

=

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

NADH

NADH

Name origin: UniProt - CHECKED (C)

CHEBI:57945

Formula: C21H27N7O14P2
Charge: -2

ChEBI compound status: CHECKED (C)

+

pyruvate

pyruvate

Name origin: UniProt - CHECKED (C)

CHEBI:15361

Formula: C3H3O3
Charge: -1

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway

Protein domains and families: PROSITE:PDOC00063

Structural data: CSA , EC2PDB

Gene Ontology: GO:0008720

CAS Registry Number: 9028-36-8

UniProtKB/Swiss-Prot: (21) [show] [UniProt]

References

Dennis, D. and Kaplan, N.O.

D and L-lactic acid dehydrogenase in Lactobacillus plantarum.

J. Biol. Chem. 235: 810-818 (1960).

[EC 1.1.1.28 created 1961]