EC - 3-methylbutanal reductase

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IntEnz Enzyme Nomenclature


Accepted name:
3-methylbutanal reductase
Systematic name:
3-methylbutanol:NAD(P)+ oxidoreductase



The enzyme purified from Saccharomyces cerevisiae catalyses the reduction of a number of straight-chain and branched aldehydes, as well as some aromatic aldehydes.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0046568


  1. van Iersel, M.F.M., Eppink, M.H.M., van Berkel, W.J.H., Rombouts, F.M. and Abee, T.
    Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae.
    Appl. Environ. Microbiol. 63 : 4079-4082 (1997). [PMID: 9327572]
  2. Ven Nedervelde, L., Verlinden, V., Philipp, D. and Debourg, A.
    Purification and characterization of yeast 3-methyl butanal reductases involved in the removal of wort carbonyls during fermentation.
    Proc. 26th Congr.-Eur. Brew. Conv. 447-454 (1997).

[EC created 2000]