IntEnz

EC 1.1.1.264 - L-idonate 5-dehydrogenase [NAD(P)⁺]

IntEnz Enzyme Nomenclature
EC 1.1.1.264

Names

Reactions

• 21172 [IUBMB]
  L-idonate

  L-idonate

  Name origin: UniProt - CHECKED (C)

  CHEBI:17796

  Formula: C6H11O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  NAD⁺

  NAD(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:57540

  Formula: C21H26N7O14P2
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  =

  5-dehydro-D-gluconate

  5-dehydro-D-gluconate

  Name origin: UniProt - CHECKED (C)

  CHEBI:58143

  Formula: C6H9O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  NADH

  NADH

  Name origin: UniProt - CHECKED (C)

  CHEBI:57945

  Formula: C21H27N7O14P2
  Charge: -2

  ChEBI compound status: CHECKED (C)

  
• 21176 [IUBMB]
  L-idonate

  L-idonate

  Name origin: UniProt - CHECKED (C)

  CHEBI:17796

  Formula: C6H11O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  NADP⁺

  NADP(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:58349

  Formula: C21H25N7O17P3
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  =

  5-dehydro-D-gluconate

  5-dehydro-D-gluconate

  Name origin: UniProt - CHECKED (C)

  CHEBI:58143

  Formula: C6H9O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  NADPH

  NADPH

  Name origin: UniProt - CHECKED (C)

  CHEBI:57783

  Formula: C21H26N7O17P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

Cofactor

• Zn²⁺

Comments:

The enzyme from the bacterium Escherichia coli is specific for 5-dehydro-D-gluconate. cf. EC 1.1.1.366, L-idonate 5-dehydrogenase (NAD⁺).

Links to other databases

References

1. Bausch, C., Peekhaus, N., Utz, C., Blais, T., Murray, E., Lowary, T. and Conway, T.
   Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli.
   J. Bacteriol. 180: 3704-3710 (1998). [PMID: 9658018]

[EC 1.1.1.264 created 2000, modified 2013]