EC 1.1.1.238 - 12β-hydroxysteroid dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.238

Names

Accepted name:
12β-hydroxysteroid dehydrogenase
Other name:
12β-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase
Systematic name:
12β-hydroxysteroid:NADP+ 12-oxidoreductase

Reaction

Comments:

Acts on a number of bile acids, both in their free and conjugated forms.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047521
CAS Registry Number: 118390-62-8

References

  1. Edenharder, R. and Pfützner, A.
    Characterization of NADP-dependent 12β-hydroxysteroid dehydrogenase from Clostridium paraputrificum.
    Biochim. Biophys. Acta 962: 362-370 (1988). [PMID: 3167086]

[EC 1.1.1.238 created 1992]