EC 1.1.1.235 - 8-oxocoformycin reductase

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IntEnz Enzyme Nomenclature
EC 1.1.1.235

Names

Accepted name:
8-oxocoformycin reductase
Other name:
8-ketodeoxycoformycin reductase
Systematic name:
coformycin:NADP+ 8-oxidoreductase

Reaction

Comments:

Si-specific with respect to NADPH. Also reduces 8-oxodeoxy-coformycin to the nucleoside antibiotic deoxycoformycin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047599
CAS Registry Number: 114995-16-3

References

  1. Hanvey, J.C., Hawkins, E.S., Baker, D.C. and Suhadolnick, R.J.
    8-Ketodeoxycoformycin and 8-ketocoformycin as intermediates in the biosynthesis of 2'-deoxycoformycin and coformycin.
    Biochemistry 27: 5790-5795 (1988). [PMID: 3052586]

[EC 1.1.1.235 created 1992]