EC - IMP dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
IMP dehydrogenase
Other names:
IMP oxidoreductase
inosinate dehydrogenase
inosine 5'-monophosphate dehydrogenase
inosine monophosphate dehydrogenase
inosine monophosphate oxidoreductase
inosine-5'-phosphate dehydrogenase
inosinic acid dehydrogenase
Systematic name:
IMP:NAD+ oxidoreductase



The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00391
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003938
CAS Registry Number: 9028-93-7
UniProtKB/Swiss-Prot: (97) [show] [UniProt]


  1. Magasanik, B., Moyed, H.S. and Gehring, L.B.
    Enzymes essential for the biosynthesis of nucleic acid guanine; inosine 5'-phosphate dehydrogenase of Aerobacter aerogenes.
    J. Biol. Chem. 226 : 339-350 (1957). [PMID: 13428767]
  2. Turner, J.F. and King, J.E.
    Inosine 5-phosphate dehydrogenase of pea seeds.
    Biochem. J. 79 : 147 (1961). [PMID: 13778733]

[EC created 1961 as EC, transferred 1984 to EC]