IntEnz

EC 1.1.1.19 - Glucuronate reductase

IntEnz Enzyme Nomenclature
EC 1.1.1.19

Names

Reaction

• 14909 [IUBMB]
  L-gulonate

  L-gulonate

  Name origin: UniProt - CHECKED (C)

  CHEBI:13115

  Formula: C6H11O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  NADP⁺

  NADP(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:58349

  Formula: C21H25N7O17P3
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  =

  aldehydo-D-glucuronate

  aldehydo-D-glucuronate

  Name origin: UniProt - CHECKED (C)

  CHEBI:142686

  Formula: C6H9O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  NADPH

  NADPH

  Name origin: UniProt - CHECKED (C)

  CHEBI:57783

  Formula: C21H26N7O17P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

Comments:

Also reduces D-galacturonate. May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP⁺)].

Links to other databases

References

1. Sivak, A. and Hoffmann-Ostenhof, O.
   Enzymes of meso-inositol catabolism in the yeast Schwanniomyces occidentalis.
   Biochim. Biophys. Acta 53: 426-428 (1961).
2. von Wartburg, J.P. and Wermoth, B.
   Aldehyde reductase.
   In: Jakoby, W.B. (Ed.) Enzymatic Basis of Detoxication vol. 1, Academic Press, New York, 1980, 249-260
3. York, J.L., Grollman, A.P. and Bublitz, C.
   TPN-L-gulonate dehydrogenase.
   Biochim. Biophys. Acta 47: 298-306 (1961).

[EC 1.1.1.19 created 1961]