EC - GDP-4-dehydro-D-rhamnose reductase

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IntEnz Enzyme Nomenclature


Accepted name:
GDP-4-dehydro-D-rhamnose reductase
Other names:
GDP-4-keto-6-deoxy-D-mannose reductase
GDP-4-keto-D-rhamnose reductase
guanosine diphosphate-4-keto-D-rhamnose reductase
GDP-6-deoxy-α-D-mannose:NAD(P)+ 4-oxidoreductase
Systematic name:
GDP-α-D-rhamnose:NAD(P)+ 4-oxidoreductase



The enzyme, which operates in the opposite direction to that shown, forms a mixture of GDP-α-D-rhamnose and its C-4 epimer, GDP-6-deoxy-α-D-talose. cf. EC, GDP-4-dehydro-6-deoxy-D-mannose reductase and EC, GDP-6-deoxy-D-talose 4-dehydrogenase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0042356
CAS Registry Number: 9075-56-3


  1. Barber, G.A.
    The synthesis of guanosine 5'-diphosphate D-rhamnose by enzymes of a higher plant.
    Biochim. Biophys. Acta 165 : 68-75 (1968). [PMID: 4386238]
  2. Winkler, N.W. and Markovitz, A.
    Guanosine diphosphate-4-keto-D-rhamnose reductase. A non-stereoselective enzyme.
    J. Biol. Chem. 246 : 5868-5876 (1971). [PMID: 4398966]

[EC created 1984]