EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.185 - L-glycol dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.185
Names
Accepted name:
L-glycol dehydrogenase
Other
names:
L-(+)-glycol:NAD(P) oxidoreductase
L-glycol:NAD(P) dehydrogenase
glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase
L-glycol:NAD(P) dehydrogenase
glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase
Systematic name:
L-glycol:NAD(P)+ oxidoreductase
Reactions
-
10324 [IUBMB]an L-glycolName origin: UniProt - CHECKED (C)Formula: C2H5O2R
Charge: 0ChEBI compound status: CHECKED (C)NADP+Name origin: UniProt - CHECKED (C)Formula: C21H25N7O17P3
Charge: -3ChEBI compound status: CHECKED (C)=a 2-hydroxycarbonylName origin: UniProt - CHECKED (C)Formula: C2H3O2R
Charge: 0ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C) -
10328 [IUBMB]an L-glycolName origin: UniProt - CHECKED (C)Formula: C2H5O2R
Charge: 0ChEBI compound status: CHECKED (C)NAD+Name origin: UniProt - CHECKED (C)Formula: C21H26N7O14P2
Charge: -1ChEBI compound status: CHECKED (C)=a 2-hydroxycarbonylName origin: UniProt - CHECKED (C)Formula: C2H3O2R
Charge: 0ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
The 2-hydroxycarbonyl compound formed can be further oxidized to a vicinal dicarbonyl compound. In the reverse direction, vicinal diketones, glyceraldehyde, glyoxal, methylglyoxal, 2-oxo-hydroxyketones and 2-ketoacid esters can be reduced.
Links to other databases
Gene Ontology:
GO:0050026
CAS Registry Number:
77967-75-0
References
-
Purification and some properties of L-glycol dehydrogenase from hen's muscle.Biochim. Biophys. Acta 659: 189-198 (1981). [PMID: 7018582]
[EC 1.1.1.185 created 1984]