IntEnz - EC 1.1.1.169

EC 1 - Oxidoreductases

EC 1.1 - Acting on the CH-OH group of donors

EC 1.1.1 - With NAD⁺ or NADP⁺ as acceptor

EC 1.1.1.169 - 2-dehydropantoate 2-reductase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.1.1.169

Names

Accepted name:

2-dehydropantoate 2-reductase

Other names:

2-ketopantoate reductase
2-ketopantoic acid reductase
2-oxopantoate reductase
ketopantoate reductase
ketopantoic acid reductase

Systematic name:

(R)-pantoate:NADP⁺ 2-oxidoreductase

Reaction

16233 [IUBMB]

(R)-pantoate

(R)-pantoate

Name origin: UniProt - CHECKED (C)

CHEBI:15980

Formula: C6H11O4
Charge: -1

ChEBI compound status: CHECKED (C)

+

NADP⁺

NADP(+)

Name origin: UniProt - CHECKED (C)

CHEBI:58349

Formula: C21H25N7O17P3
Charge: -3

ChEBI compound status: CHECKED (C)

=

2-dehydropantoate

2-dehydropantoate

Name origin: UniProt - CHECKED (C)

CHEBI:11561

Formula: C6H9O4
Charge: -1

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

NADPH

NADPH

Name origin: UniProt - CHECKED (C)

CHEBI:57783

Formula: C21H26N7O17P3
Charge: -4

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0008677

CAS Registry Number: 37211-74-8

UniProtKB/Swiss-Prot: (31) [show] [UniProt]

References

King, H.L., Jr. and Wilken, D.R.

Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase.

J. Biol. Chem. 247: 4689-4695 (1972).

[EC 1.1.1.169 created 1976]