EC 1.1.1.16 - Galactitol 2-dehydrogenase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.1.1.16

Names

Accepted name:
galactitol 2-dehydrogenase
Other names:
dulcitol dehydrogenase
AtuSorbD
galactitol:NAD+ 2-oxidoreductase
Systematic name:
galactitol:NAD+ 2-oxidoreductase (D-tagatose-forming)

Reaction

Comments:

Also converts other alditols containing an L-threo-configuration adjacent to a primary alcohol group into the corresponding sugars. The enzyme from Agrobacterium rubrum C58 is part of D-altritol and galactitol degradation pathways.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047713
CAS Registry Number: 9028-23-3

References

  1. Shaw, D.R.D.
    Polyol dehydrogenases 3. Galactitol dehydrogenase and D-iditol dehydrogenase.
    Biochem. J. 64: 394-405 (1956).
  2. Wichelecki, D. J., Vetting, M. W., Chou, L., Al-Obaidi, N., Bouvier, J. T., Almo, S. C., Gerlt, J. A.
    ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel D-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.
    J. Biol. Chem. 290: 28963-28976 (2015). [PMID: 26472925]

[EC 1.1.1.16 created 1961]