EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.16 - Galactitol 2-dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.16
Names
Accepted name:
galactitol 2-dehydrogenase
Other
names:
dulcitol dehydrogenase
AtuSorbD
galactitol:NAD+ 2-oxidoreductase
AtuSorbD
galactitol:NAD+ 2-oxidoreductase
Systematic name:
galactitol:NAD+ 2-oxidoreductase (D-tagatose-forming)
Reaction
- galactitol + NAD+ = D-tagatose + NADH + H+
Comments:
Also converts other alditols containing an L-threo-configuration adjacent to a primary alcohol group into the corresponding sugars. The enzyme from Agrobacterium rubrum C58 is part of D-altritol and galactitol degradation pathways.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0047713
CAS Registry Number:
9028-23-3
UniProtKB/Swiss-Prot:
References
-
Polyol dehydrogenases 3. Galactitol dehydrogenase and D-iditol dehydrogenase.Biochem. J. 64 : 394-405 (1956).
-
ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel D-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.J. Biol. Chem. 290 : 28963-28976 (2015). [PMID: 26472925]
[EC 1.1.1.16 created 1961]