EC - 21-hydroxysteroid dehydrogenase (NADP+)

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IntEnz Enzyme Nomenclature


Accepted name:
21-hydroxysteroid dehydrogenase (NADP+)
Other names:
21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase
21-hydroxy steroid dehydrogenase
21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate)
NADP-21-hydroxysteroid dehydrogenase
Systematic name:
21-hydroxysteroid:NADP+ 21-oxidoreductase



Acts on a number of 21-hydroxycorticosteroids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047008
CAS Registry Number: 37250-76-3


  1. Monder, C. and White, A.
    The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases.
    J. Biol. Chem. 240: 71-77 (1965).

[EC created 1972]