EC - 11β-hydroxysteroid dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
11β-hydroxysteroid dehydrogenase
Other names:
11β-hydroxy steroid dehydrogenase
β-hydroxysteroid dehydrogenase
corticosteroid 11-reductase
corticosteroid 11β-dehydrogenase
dehydrogenase, 11β-hydroxy steroid
Systematic name:
11β-hydroxysteroid:NADP+ 11-oxidoreductase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00060
Structural data: CSA , EC2PDB
Gene Ontology: GO:0070524
CAS Registry Number: 9041-46-7
UniProtKB/Swiss-Prot: (15) [show] [UniProt]


  1. Agarwal, A.K., Monder, C., Eckstein, B. and White, P.C.
    Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase.
    J. Biol. Chem. 264 : 18939-18943 (1989). [PMID: 2808402]
  2. Bush, I.E., Hunter, S.A. and Meigs, R.A.
    Metabolism of 11-oxygenated steroids. Metabolism in vitro by preparations of liver.
    Biochem. J. 107 : 239-258 (1968). [PMID: 4384445]
  3. Lakshmi, V. and Monder, C.
    Purification and characterization of the corticosteroid 11β-dehydrogenase component of the rat liver 11β-hydroxysteroid dehydrogenase complex.
    Endocrinology 123 : 2390-2398 (1988). [PMID: 3139396]
  4. Phillips, D.M., Lakshmi, V. and Monder, C.
    Corticosteroid 11β-dehydrogenase in rat testis.
    Endocrinology 125 : 209-216 (1989). [PMID: 2661206]

[EC created 1972]