IntEnz

EC 1.1.1.112 - Indanol dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.112

Names

Accepted name:

indanol dehydrogenase

Systematic name:

indan-1-ol:NAD(P)⁺ 1-oxidoreductase

Reactions

16317 [IUBMB]

indan-1-ol

indan-1-ol

Name origin: UniProt - CHECKED (C)

CHEBI:16697

Formula: C9H10O
Charge: 0

ChEBI compound status: CHECKED (C)

+

NAD⁺

NAD(+)

Name origin: UniProt - CHECKED (C)

CHEBI:57540

Formula: C21H26N7O14P2
Charge: -1

ChEBI compound status: CHECKED (C)

=

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

indan-1-one

indan-1-one

Name origin: UniProt - CHECKED (C)

CHEBI:17404

Formula: C9H8O
Charge: 0

ChEBI compound status: CHECKED (C)

+

NADH

NADH

Name origin: UniProt - CHECKED (C)

CHEBI:57945

Formula: C21H27N7O14P2
Charge: -2

ChEBI compound status: CHECKED (C)
16321 [IUBMB]

indan-1-ol

indan-1-ol

Name origin: UniProt - CHECKED (C)

CHEBI:16697

Formula: C9H10O
Charge: 0

ChEBI compound status: CHECKED (C)

+

NADP⁺

NADP(+)

Name origin: UniProt - CHECKED (C)

CHEBI:58349

Formula: C21H25N7O17P3
Charge: -3

ChEBI compound status: CHECKED (C)

=

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

indan-1-one

indan-1-one

Name origin: UniProt - CHECKED (C)

CHEBI:17404

Formula: C9H8O
Charge: 0

ChEBI compound status: CHECKED (C)

+

NADPH

NADPH

Name origin: UniProt - CHECKED (C)

CHEBI:57783

Formula: C21H26N7O17P3
Charge: -4

ChEBI compound status: CHECKED (C)

Comments:

3(20)α-Hydroxysteroids are also oxidized, more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0047718

CAS Registry Number: 37250-43-4

UniProtKB/Swiss-Prot:

Q04828

AK1C1_HUMAN

Q95JH7

AK1C1_MACFA

Q95JH6

AK1C1_MACFU

Q5REQ0

AK1C1_PONAB

P42330

AK1C3_HUMAN

Q5R7C9

AK1C3_PONAB

References

Billings, R.E., Sullivan, H.R. and McMahon, R.E.

The dehydrogenation of 1-indanol by a soluble oxidoreductase from bovine liver.

J. Biol. Chem. 246: 3512-3517 (1971). [PMID: 4397102]
Hara, A., Nakagawa, M., Taniguchi, H. and Sawada, H.

3(20)α-Hydroxysteroid dehydrogenase activity of monkey liver indanol dehydrogenase.

J. Biochem. (Tokyo) 106: 900-903 (1989). [PMID: 2559080]

[EC 1.1.1.112 created 1972]

EC 1 - Oxidoreductases