EC - 3-oxoacyl-[acyl-carrier-protein] reductase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
3-oxoacyl-[acyl-carrier-protein] reductase
Other names:
3-ketoacyl acyl carrier protein reductase
β-ketoacyl acyl carrier protein (ACP) reductase
β-ketoacyl reductase
β-ketoacyl thioester reductase
β-ketoacyl-ACP reductase
β-ketoacyl-[acyl-carrier protein](ACP) reductase
β-ketoacyl-acyl carrier protein reductase
NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase
Systematic name:
(3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductase



Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00060
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004316
CAS Registry Number: 37250-34-3
UniProtKB/Swiss-Prot: (74) [show] [UniProt]


  1. Prescott, D.J. and Vagelos, P.R.
    Acyl carrier protein.
    Adv. Enzymol. Relat. Areas Mol. Biol. 36 : 269-311 (1972). [PMID: 4561013]
  2. Shimakata, T. and Stumpf, P.K.
    Purification and characterizations of β-ketoacyl-[acyl-carrier-protein] reductase, β-hydroxyacyl-[acyl-carrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea leaves.
    Arch. Biochem. Biophys. 218 : 77-91 (1982). [PMID: 6756317]
  3. Toomey, R.E. and Wakil, S.J.
    Studies on the mechanism of fatty acid synthesis. XV. Preparation and general properties of β-ketoacyl acyl carrier protein reductase from Escherichia coli.
    Biochim. Biophys. Acta 116 : 189-197 (1966). [PMID: 4381013]

[EC created 1972, modified 1976]