EC 1 - Oxidoreductases


All enzymes catalysing oxido-reductions belong in this class. The substrate oxidized is regarded as hydrogen or electron donor. The classification is based on 'donor:acceptor oxidoreductase'. The common name is 'dehydrogenase', wherever this is possible; as an alternative, 'acceptor reductase' can be used. 'Oxidase' is used only where O2 is an acceptor. Classification is difficult in some cases, because of the lack of specificity towards the acceptor.


EC 1.1
Acting on the CH-OH group of donors
EC 1.2
Acting on the aldehyde or oxo group of donors
EC 1.3
Acting on the CH-CH group of donors
EC 1.4
Acting on the CH-NH2 group of donors
EC 1.5
Acting on the CH-NH group of donors
EC 1.6
Acting on NADH or NADPH
EC 1.7
Acting on other nitrogenous compounds as donors
EC 1.8
Acting on a sulfur group of donors
EC 1.9
Acting on a heme group of donors
EC 1.10
Acting on diphenols and related substances as donors
EC 1.11
Acting on a peroxide as acceptor
EC 1.12
Acting on hydrogen as donors
EC 1.13
Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2
EC 1.14
Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.15
Acting on superoxide as acceptor
EC 1.16
Oxidizing metal ions
EC 1.17
Acting on CH or CH2 groups
EC 1.18
Acting on iron-sulfur proteins as donors
EC 1.19
Acting on reduced flavodoxin as donor
EC 1.20
Acting on phosphorus or arsenic in donors
EC 1.21
Catalyzing the reaction X-H + Y-H = 'X-Y'
EC 1.22
Acting on halogen in donors
EC 1.23
Reducing C-O-C group as acceptor
EC 1.97
Other oxidoreductases
EC 1.98
Enzymes using H2 as reductant
EC 1.99
Other enzymes using O2 as oxidant