EC 1.7.1.9 - Nitroquinoline-N-oxide reductase

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IntEnz Enzyme Nomenclature
EC 1.7.1.9

Names

Accepted name:
nitroquinoline-N-oxide reductase
Other names:
4-nitroquinoline 1-oxide reductase
4NQO reductase
NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase
NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase
Systematic name:
4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050465
CAS Registry Number: 37256-35-2

References

  1. Toriyama, N.
    [Metabolism of quinoline derivatives. On the reducing enzyme of 4-nitroquinoline-N-oxide.] (in Japanese)
    Nichidai Igaku Zasshi 24 : 423-432 (1965).
  2. Stanley, J.S., York, J.L. and Benson AM.
    Nitroreductases and glutathione transferases that act on 4-nitroquinoline 1-oxide and their differential induction by butylated hydroxyanisole in mice.
    Cancer Res. 52 : 58-63 (1992). [PMID: 1370076]

[EC 1.7.1.9 created 1972 as EC 1.6.6.10, transferred 2002 to EC 1.7.1.9]