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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 18775313

Journal: Cell (0092-8674)

Year of Publication: 2008

Title: UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

Author List: Alexandru G., Graumann J., Smith GT., Kolawa NJ., Fang R., Deshaies RJ.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Apoptosis - Interactions involving proteins with a function related to apoptosis

Experiment (5 interactions)

Accession: EBI-2009857

Name: alexandru-2008-5

Host organism: Homo sapiens transformed primary embryonal kidney cells

Organism: Homo sapiens transformed primary embryonal kidney cells

Accession: EBI-307628

Name: human-293

Description: Homo sapiens transformed primary embryonal kidney cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: mudpit

Participant identification method: mudpit
Accession: EBI-933988

Name: mudpit

Description: multidimensional protein identification technology

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0658
-
identity
pubmed
11231557
-
primary-reference


Annotations:
Topic
Text
definition
MudPIT is a method for rapid and large-scale protein identification by multidimensional liquid chromatography associated with tandem mass spectrometry. The chromatography step consists of strong cation exchange material back-to-back with reversed phase material inside fused silica capillaries. The peptides bound to the cation-exchange resin are freed by the gradually increasing salt concentration of the buffer and are subsequently retained by the reversed phase resin. Increasing buffers hydrophobicity progressively elute peptides from the reversed phase packing directly into the mass spectrometer. Typically this mass spectrometer will be a tandem electrospray, so peptides undergo ionization in the liquid phase, are separated in a primary mass spectrometer, analysed in the second mass spectrometer and identified.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
galex@caltech.edu, deshaies@caltech.edu
Cells treated with DMSO
Only protein-protein interactions
-
53
imex curation

Interaction

Accession: EBI-2010017

Name: saks1-plaa-3

Description: Interactors of SAKS1 identified by mass spectromtery

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Supp. Table 2
UBXD1=UBXN6, UBXD2=UBXN4, UBXD3=UBXN10, UBXD4=UBXN2A, UBXD5=Socius=UBXN11, UBXD6=Rep8=UBXN8, UBXD7=UBXN7, SAKS1=U33K=UBXN1, UBXD8=ETEA=FAF2, p37=UBXN2B, UBXD7=UBXN7, ASPL=ASPC1=TUG

Participants (18)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
1
EBI-1058647
 logo
UBXN1
SAKS1
SAPK substrate protein 1

[+1]
UBX domain-containing protein 1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: UBX domain-containing protein 1

Participant: UBX domain-containing protein 1

Accession: EBI-2010031

Name: EBI-1058647

P
Participant: UBX domain-containing protein 1

Participant: UBX domain-containing protein 1

Accession: EBI-2010031

Name: EBI-1058647

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: UBX domain-containing protein 1

Participant: UBX domain-containing protein 1

Accession: EBI-2010031

Name: EBI-1058647

Stoichiometry: 0.0

F
Participant: UBX domain-containing protein 1

Participant: UBX domain-containing protein 1

Accession: EBI-2010031

Name: EBI-1058647

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
region
  • ?-?
  • A
    Feature: EBI-2010032

    Feature: region

    Accession: EBI-2010032

    Name: region


    C
    Participant: UBX domain-containing protein 1

    Participant: UBX domain-containing protein 1

    Accession: EBI-2010031

    Name: EBI-1058647

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-1046367
     logo
    AMFR
    RNF45
    Autocrine motility factor receptor

    [+3]
    E3 ubiquitin-protein ligase AMFR
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase AMFR

    Participant: E3 ubiquitin-protein ligase AMFR

    Accession: EBI-2010020

    Name: EBI-1046367

    P
    Participant: E3 ubiquitin-protein ligase AMFR

    Participant: E3 ubiquitin-protein ligase AMFR

    Accession: EBI-2010020

    Name: EBI-1046367

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase AMFR

    Participant: E3 ubiquitin-protein ligase AMFR

    Accession: EBI-2010020

    Name: EBI-1046367

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase AMFR

    Participant: E3 ubiquitin-protein ligase AMFR

    Accession: EBI-2010020

    Name: EBI-1046367

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase AMFR

    Participant: E3 ubiquitin-protein ligase AMFR

    Accession: EBI-2010020

    Name: EBI-1046367

    Confidences:

    Type
    Value
    No records found.

    3
    EBI-1995940
     logo
    UBR4
    KIAA0462
    KIAA1307

    [+7]
    E3 ubiquitin-protein ligase UBR4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase UBR4

    Participant: E3 ubiquitin-protein ligase UBR4

    Accession: EBI-2010021

    Name: EBI-1995940

    P
    Participant: E3 ubiquitin-protein ligase UBR4

    Participant: E3 ubiquitin-protein ligase UBR4

    Accession: EBI-2010021

    Name: EBI-1995940

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase UBR4

    Participant: E3 ubiquitin-protein ligase UBR4

    Accession: EBI-2010021

    Name: EBI-1995940

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase UBR4

    Participant: E3 ubiquitin-protein ligase UBR4

    Accession: EBI-2010021

    Name: EBI-1995940

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase UBR4

    Participant: E3 ubiquitin-protein ligase UBR4

    Accession: EBI-2010021

    Name: EBI-1995940

    Confidences:

    Type
    Value
    No records found.

    4
    EBI-1996038
     logo
    PJA2
    KIAA0438
    RNF131

    [+2]
    E3 ubiquitin-protein ligase Praja-2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase Praja-2

    Participant: E3 ubiquitin-protein ligase Praja-2

    Accession: EBI-2010022

    Name: EBI-1996038

    P
    Participant: E3 ubiquitin-protein ligase Praja-2

    Participant: E3 ubiquitin-protein ligase Praja-2

    Accession: EBI-2010022

    Name: EBI-1996038

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase Praja-2

    Participant: E3 ubiquitin-protein ligase Praja-2

    Accession: EBI-2010022

    Name: EBI-1996038

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase Praja-2

    Participant: E3 ubiquitin-protein ligase Praja-2

    Accession: EBI-2010022

    Name: EBI-1996038

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase Praja-2

    Participant: E3 ubiquitin-protein ligase Praja-2

    Accession: EBI-2010022

    Name: EBI-1996038

    Confidences:

    Type
    Value
    No records found.

    5
    EBI-1237260
     logo
    UBR2
    C6orf133
    KIAA0349

    [+4]
    E3 ubiquitin-protein ligase UBR2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase UBR2

    Participant: E3 ubiquitin-protein ligase UBR2

    Accession: EBI-2010023

    Name: EBI-1237260

    P
    Participant: E3 ubiquitin-protein ligase UBR2

    Participant: E3 ubiquitin-protein ligase UBR2

    Accession: EBI-2010023

    Name: EBI-1237260

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase UBR2

    Participant: E3 ubiquitin-protein ligase UBR2

    Accession: EBI-2010023

    Name: EBI-1237260

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase UBR2

    Participant: E3 ubiquitin-protein ligase UBR2

    Accession: EBI-2010023

    Name: EBI-1237260

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase UBR2

    Participant: E3 ubiquitin-protein ligase UBR2

    Accession: EBI-2010023

    Name: EBI-1237260

    Confidences:

    Type
    Value
    No records found.

    6
    EBI-456129
     logo
    CUL3
    KIAA0617
    Cullin-3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cullin-3

    Participant: Cullin-3

    Accession: EBI-2010024

    Name: EBI-456129

    P
    Participant: Cullin-3

    Participant: Cullin-3

    Accession: EBI-2010024

    Name: EBI-456129

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cullin-3

    Participant: Cullin-3

    Accession: EBI-2010024

    Name: EBI-456129

    Stoichiometry: 0.0

    F
    Participant: Cullin-3

    Participant: Cullin-3

    Accession: EBI-2010024

    Name: EBI-456129

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cullin-3

    Participant: Cullin-3

    Accession: EBI-2010024

    Name: EBI-456129

    Confidences:

    Type
    Value
    No records found.

    7
    EBI-1641720
     logo
    UBE4B
    HDNB1
    KIAA0684

    [+4]
    Ubiquitin conjugation factor E4 B
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ubiquitin conjugation factor E4 B

    Participant: Ubiquitin conjugation factor E4 B

    Accession: EBI-2010025

    Name: EBI-1641720

    P
    Participant: Ubiquitin conjugation factor E4 B

    Participant: Ubiquitin conjugation factor E4 B

    Accession: EBI-2010025

    Name: EBI-1641720

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Ubiquitin conjugation factor E4 B

    Participant: Ubiquitin conjugation factor E4 B

    Accession: EBI-2010025

    Name: EBI-1641720

    Stoichiometry: 0.0

    F
    Participant: Ubiquitin conjugation factor E4 B

    Participant: Ubiquitin conjugation factor E4 B

    Accession: EBI-2010025

    Name: EBI-1641720

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ubiquitin conjugation factor E4 B

    Participant: Ubiquitin conjugation factor E4 B

    Accession: EBI-2010025

    Name: EBI-1641720

    Confidences:

    Type
    Value
    No records found.

    8
    EBI-358329
     logo
    EDD
    EDD1
    E3 ubiquitin-protein ligase, HECT domain-containing 1

    [+6]
    E3 ubiquitin-protein ligase UBR5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase UBR5

    Participant: E3 ubiquitin-protein ligase UBR5

    Accession: EBI-2010026

    Name: EBI-358329

    P
    Participant: E3 ubiquitin-protein ligase UBR5

    Participant: E3 ubiquitin-protein ligase UBR5

    Accession: EBI-2010026

    Name: EBI-358329

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase UBR5

    Participant: E3 ubiquitin-protein ligase UBR5

    Accession: EBI-2010026

    Name: EBI-358329

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase UBR5

    Participant: E3 ubiquitin-protein ligase UBR5

    Accession: EBI-2010026

    Name: EBI-358329

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase UBR5

    Participant: E3 ubiquitin-protein ligase UBR5

    Accession: EBI-2010026

    Name: EBI-358329

    Confidences:

    Type
    Value
    No records found.

    9
    EBI-710091
     logo
    BTBD2
    BTB/POZ domain-containing protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: BTB/POZ domain-containing protein 2

    Participant: BTB/POZ domain-containing protein 2

    Accession: EBI-2010027

    Name: EBI-710091

    P
    Participant: BTB/POZ domain-containing protein 2

    Participant: BTB/POZ domain-containing protein 2

    Accession: EBI-2010027

    Name: EBI-710091

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: BTB/POZ domain-containing protein 2

    Participant: BTB/POZ domain-containing protein 2

    Accession: EBI-2010027

    Name: EBI-710091

    Stoichiometry: 0.0

    F
    Participant: BTB/POZ domain-containing protein 2

    Participant: BTB/POZ domain-containing protein 2

    Accession: EBI-2010027

    Name: EBI-710091

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: BTB/POZ domain-containing protein 2

    Participant: BTB/POZ domain-containing protein 2

    Accession: EBI-2010027

    Name: EBI-710091

    Confidences:

    Type
    Value
    No records found.

    10
    EBI-740929
     logo
    KLHL12
    C3IP1
    DKIR homolog

    [+1]
    Kelch-like protein 12
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kelch-like protein 12

    Participant: Kelch-like protein 12

    Accession: EBI-2010028

    Name: EBI-740929

    P
    Participant: Kelch-like protein 12

    Participant: Kelch-like protein 12

    Accession: EBI-2010028

    Name: EBI-740929

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kelch-like protein 12

    Participant: Kelch-like protein 12

    Accession: EBI-2010028

    Name: EBI-740929

    Stoichiometry: 0.0

    F
    Participant: Kelch-like protein 12

    Participant: Kelch-like protein 12

    Accession: EBI-2010028

    Name: EBI-740929

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kelch-like protein 12

    Participant: Kelch-like protein 12

    Accession: EBI-2010028

    Name: EBI-740929

    Confidences:

    Type
    Value
    No records found.

    11
    EBI-711736
     logo
    UBR1
    RING-type E3 ubiquitin transferase UBR1
    N-recognin-1

    [+2]
    E3 ubiquitin-protein ligase UBR1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase UBR1

    Participant: E3 ubiquitin-protein ligase UBR1

    Accession: EBI-2010029

    Name: EBI-711736

    P
    Participant: E3 ubiquitin-protein ligase UBR1

    Participant: E3 ubiquitin-protein ligase UBR1

    Accession: EBI-2010029

    Name: EBI-711736

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase UBR1

    Participant: E3 ubiquitin-protein ligase UBR1

    Accession: EBI-2010029

    Name: EBI-711736

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase UBR1

    Participant: E3 ubiquitin-protein ligase UBR1

    Accession: EBI-2010029

    Name: EBI-711736

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase UBR1

    Participant: E3 ubiquitin-protein ligase UBR1

    Accession: EBI-2010029

    Name: EBI-711736

    Confidences:

    Type
    Value
    No records found.

    12
    EBI-359390
     logo
    CUL1
    Cullin-1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cullin-1

    Participant: Cullin-1

    Accession: EBI-2010030

    Name: EBI-359390

    P
    Participant: Cullin-1

    Participant: Cullin-1

    Accession: EBI-2010030

    Name: EBI-359390

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cullin-1

    Participant: Cullin-1

    Accession: EBI-2010030

    Name: EBI-359390

    Stoichiometry: 0.0

    F
    Participant: Cullin-1

    Participant: Cullin-1

    Accession: EBI-2010030

    Name: EBI-359390

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cullin-1

    Participant: Cullin-1

    Accession: EBI-2010030

    Name: EBI-359390

    Confidences:

    Type
    Value
    No records found.

    13
    EBI-514538
     logo
    BIRC2
    API1
    MIHB

    [+7]
    Baculoviral IAP repeat-containing protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Baculoviral IAP repeat-containing protein 2

    Participant: Baculoviral IAP repeat-containing protein 2

    Accession: EBI-2010034

    Name: EBI-514538

    P
    Participant: Baculoviral IAP repeat-containing protein 2

    Participant: Baculoviral IAP repeat-containing protein 2

    Accession: EBI-2010034

    Name: EBI-514538

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Baculoviral IAP repeat-containing protein 2

    Participant: Baculoviral IAP repeat-containing protein 2

    Accession: EBI-2010034

    Name: EBI-514538

    Stoichiometry: 0.0

    F
    Participant: Baculoviral IAP repeat-containing protein 2

    Participant: Baculoviral IAP repeat-containing protein 2

    Accession: EBI-2010034

    Name: EBI-514538

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Baculoviral IAP repeat-containing protein 2

    Participant: Baculoviral IAP repeat-containing protein 2

    Accession: EBI-2010034

    Name: EBI-514538

    Confidences:

    Type
    Value
    No records found.

    14
    EBI-456179
     logo
    CUL2
    Cullin-2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cullin-2

    Participant: Cullin-2

    Accession: EBI-2010035

    Name: EBI-456179

    P
    Participant: Cullin-2

    Participant: Cullin-2

    Accession: EBI-2010035

    Name: EBI-456179

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cullin-2

    Participant: Cullin-2

    Accession: EBI-2010035

    Name: EBI-456179

    Stoichiometry: 0.0

    F
    Participant: Cullin-2

    Participant: Cullin-2

    Accession: EBI-2010035

    Name: EBI-456179

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cullin-2

    Participant: Cullin-2

    Accession: EBI-2010035

    Name: EBI-456179

    Confidences:

    Type
    Value
    No records found.

    15
    EBI-350322
     logo
    XAP1
    DDB1
    Damage-specific DNA-binding protein 1

    [+7]
    DNA damage-binding protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA damage-binding protein 1

    Participant: DNA damage-binding protein 1

    Accession: EBI-2010036

    Name: EBI-350322

    P
    Participant: DNA damage-binding protein 1

    Participant: DNA damage-binding protein 1

    Accession: EBI-2010036

    Name: EBI-350322

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA damage-binding protein 1

    Participant: DNA damage-binding protein 1

    Accession: EBI-2010036

    Name: EBI-350322

    Stoichiometry: 0.0

    F
    Participant: DNA damage-binding protein 1

    Participant: DNA damage-binding protein 1

    Accession: EBI-2010036

    Name: EBI-350322

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA damage-binding protein 1

    Participant: DNA damage-binding protein 1

    Accession: EBI-2010036

    Name: EBI-350322

    Confidences:

    Type
    Value
    No records found.

    16
    EBI-473695
     logo
    KBTBD7
    Kelch repeat and BTB domain-containing protein 7
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kelch repeat and BTB domain-containing protein 7

    Participant: Kelch repeat and BTB domain-containing protein 7

    Accession: EBI-2010037

    Name: EBI-473695

    P
    Participant: Kelch repeat and BTB domain-containing protein 7

    Participant: Kelch repeat and BTB domain-containing protein 7

    Accession: EBI-2010037

    Name: EBI-473695

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kelch repeat and BTB domain-containing protein 7

    Participant: Kelch repeat and BTB domain-containing protein 7

    Accession: EBI-2010037

    Name: EBI-473695

    Stoichiometry: 0.0

    F
    Participant: Kelch repeat and BTB domain-containing protein 7

    Participant: Kelch repeat and BTB domain-containing protein 7

    Accession: EBI-2010037

    Name: EBI-473695

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kelch repeat and BTB domain-containing protein 7

    Participant: Kelch repeat and BTB domain-containing protein 7

    Accession: EBI-2010037

    Name: EBI-473695

    Confidences:

    Type
    Value
    No records found.

    17
    EBI-1996072
     logo
    KLHL22
    Kelch-like protein 22
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-2010038

    Name: EBI-1996072

    P
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-2010038

    Name: EBI-1996072

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-2010038

    Name: EBI-1996072

    Stoichiometry: 0.0

    F
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-2010038

    Name: EBI-1996072

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-2010038

    Name: EBI-1996072

    Confidences:

    Type
    Value
    No records found.

    18
    EBI-1996544
     logo
    RLIM
    RNF12
    RING finger protein 12

    [+4]
    E3 ubiquitin-protein ligase RLIM
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase RLIM

    Participant: E3 ubiquitin-protein ligase RLIM

    Accession: EBI-2010039

    Name: EBI-1996544

    P
    Participant: E3 ubiquitin-protein ligase RLIM

    Participant: E3 ubiquitin-protein ligase RLIM

    Accession: EBI-2010039

    Name: EBI-1996544

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase RLIM

    Participant: E3 ubiquitin-protein ligase RLIM

    Accession: EBI-2010039

    Name: EBI-1996544

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase RLIM

    Participant: E3 ubiquitin-protein ligase RLIM

    Accession: EBI-2010039

    Name: EBI-1996544

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase RLIM

    Participant: E3 ubiquitin-protein ligase RLIM

    Accession: EBI-2010039

    Name: EBI-1996544

    Confidences:

    Type
    Value
    No records found.


    Graphical Representation of Experimental Features