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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 28514442

Journal: Nature

Year of Publication: 2017

Title: Architecture of the human interactome defines protein communities and disease networks.

Author List: Huttlin EL., Bruckner RJ., Paulo JA., Cannon JR., Ting L., Baltier K., Colby G., Gebreab F., Gygi MP., Parzen H., Szpyt J., Tam S., Zarraga G., Pontano-Vaites L., Swarup S., White AE., Schweppe DK., Rad R., Erickson BK., Obar RA., Guruharsha KG., Li K., Artavanis-Tsakonas S., Gygi SP., Harper JW.

Cross References:

Experiment (6 interactions)

Accession: EBI-21902672

Name: huttlin-2017-5

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
edward_huttlin@hms.harvard.edu,steven.gygi@hms.harvard.edu,wade_harper@hms.harvard.edu
imex curation

Interaction

Accession: EBI-21905461

Name: ywhag-abl1-1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Supplementary table 2 (14-3-3 sheet)

Participants (365)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12345678910pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12345678910pp
1
EBI-359832
 logo
YWHAG
Protein kinase C inhibitor protein 1
14-3-3 protein gamma
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 14-3-3 protein gamma

Participant: 14-3-3 protein gamma

Accession: EBI-21905463

Name: EBI-359832

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: 14-3-3 protein gamma

Participant: 14-3-3 protein gamma

Accession: EBI-21905463

Name: EBI-359832

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 14-3-3 protein gamma

Participant: 14-3-3 protein gamma

Accession: EBI-21905463

Name: EBI-359832

Stoichiometry: 0.0

F
Participant: 14-3-3 protein gamma

Participant: 14-3-3 protein gamma

Accession: EBI-21905463

Name: EBI-359832

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
C-terminal HA-flag tag
  • c-c
  • A
    Feature: EBI-21905465

    Feature: C-terminal HA-flag tag

    Accession: EBI-21905465

    Name: C-terminal HA-flag tag


    C
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-21905463

    Name: EBI-359832

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-8531039
     logo
    FOXO6
    Forkhead box protein O6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21905468

    Name: EBI-8531039

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21905468

    Name: EBI-8531039

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21905468

    Name: EBI-8531039

    Stoichiometry: 0.0

    F
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21905468

    Name: EBI-8531039

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21905468

    Name: EBI-8531039

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.999329658985178
    Non-specific binding CompPASS-Plus score: 8.9595570162497903E-8
    False-positive CompPASS-Plus score: 6.7025141925223695E-4

    3
    EBI-715576
     logo
    Antigen NY-CO-9
    HDAC5
    KIAA0600
    Histone deacetylase 5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21905474

    Name: EBI-715576

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21905474

    Name: EBI-715576

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21905474

    Name: EBI-715576

    Stoichiometry: 0.0

    F
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21905474

    Name: EBI-715576

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21905474

    Name: EBI-715576

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999896927628196
    Non-specific binding CompPASS-Plus score: 1.9715595251554799E-8
    False-positive CompPASS-Plus score: 1.01100812332143E-6

    4
    EBI-2339271
     logo
    SH2D3A
    NSP1
    Novel SH2-containing protein 1

    [+1]
    SH2 domain-containing protein 3A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: SH2 domain-containing protein 3A

    Participant: SH2 domain-containing protein 3A

    Accession: EBI-21905480

    Name: EBI-2339271

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: SH2 domain-containing protein 3A

    Participant: SH2 domain-containing protein 3A

    Accession: EBI-21905480

    Name: EBI-2339271

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: SH2 domain-containing protein 3A

    Participant: SH2 domain-containing protein 3A

    Accession: EBI-21905480

    Name: EBI-2339271

    Stoichiometry: 0.0

    F
    Participant: SH2 domain-containing protein 3A

    Participant: SH2 domain-containing protein 3A

    Accession: EBI-21905480

    Name: EBI-2339271

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: SH2 domain-containing protein 3A

    Participant: SH2 domain-containing protein 3A

    Accession: EBI-21905480

    Name: EBI-2339271

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98828844534919302
    Non-specific binding CompPASS-Plus score: 6.2187499213850201E-6
    False-positive CompPASS-Plus score: 1.1705335900885299E-2

    5
    EBI-10962518
     logo
    FAM13A
    FAM13A1
    KIAA0914
    Protein FAM13A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein FAM13A

    Participant: Protein FAM13A

    Accession: EBI-21905486

    Name: EBI-10962518

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Protein FAM13A

    Participant: Protein FAM13A

    Accession: EBI-21905486

    Name: EBI-10962518

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein FAM13A

    Participant: Protein FAM13A

    Accession: EBI-21905486

    Name: EBI-10962518

    Stoichiometry: 0.0

    F
    Participant: Protein FAM13A

    Participant: Protein FAM13A

    Accession: EBI-21905486

    Name: EBI-10962518

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein FAM13A

    Participant: Protein FAM13A

    Accession: EBI-21905486

    Name: EBI-10962518

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999767572906795
    Non-specific binding CompPASS-Plus score: 1.9569531579660498E-6
    False-positive CompPASS-Plus score: 3.67317773693451E-7

    6
    EBI-1055880
     logo
    SRRM1
    SRM160
    Ser/Arg-related nuclear matrix protein

    [+1]
    Serine/arginine repetitive matrix protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/arginine repetitive matrix protein 1

    Participant: Serine/arginine repetitive matrix protein 1

    Accession: EBI-21905492

    Name: EBI-1055880

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/arginine repetitive matrix protein 1

    Participant: Serine/arginine repetitive matrix protein 1

    Accession: EBI-21905492

    Name: EBI-1055880

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/arginine repetitive matrix protein 1

    Participant: Serine/arginine repetitive matrix protein 1

    Accession: EBI-21905492

    Name: EBI-1055880

    Stoichiometry: 0.0

    F
    Participant: Serine/arginine repetitive matrix protein 1

    Participant: Serine/arginine repetitive matrix protein 1

    Accession: EBI-21905492

    Name: EBI-1055880

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/arginine repetitive matrix protein 1

    Participant: Serine/arginine repetitive matrix protein 1

    Accession: EBI-21905492

    Name: EBI-1055880

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.77944154274271904
    Non-specific binding CompPASS-Plus score: 0.22055845725728099
    False-positive CompPASS-Plus score: 5.6768073261782797E-17

    7
    EBI-1046479
     logo
    DENN domain-containing protein 4A
    DENND4A
    IRLB

    [+1]
    C-myc promoter-binding protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21905498

    Name: EBI-1046479

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21905498

    Name: EBI-1046479

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21905498

    Name: EBI-1046479

    Stoichiometry: 0.0

    F
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21905498

    Name: EBI-1046479

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21905498

    Name: EBI-1046479

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999997404859198
    Non-specific binding CompPASS-Plus score: 2.5951157879679201E-8
    False-positive CompPASS-Plus score: 2.5016182475109902E-13

    8
    EBI-21550113
     logo
    SPEG
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-21905504

    Name: EBI-21550113

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant:

    Participant:

    Accession: EBI-21905504

    Name: EBI-21550113

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant:

    Participant:

    Accession: EBI-21905504

    Name: EBI-21550113

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-21905504

    Name: EBI-21550113

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-21905504

    Name: EBI-21550113

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999955826834397
    Non-specific binding CompPASS-Plus score: 3.3928352734100301E-7
    False-positive CompPASS-Plus score: 1.02448128364737E-7

    9
    EBI-713738
     logo
    p21-activated kinase 4
    PAK4
    KIAA1142
    Serine/threonine-protein kinase PAK 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21905510

    Name: EBI-713738

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21905510

    Name: EBI-713738

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21905510

    Name: EBI-713738

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21905510

    Name: EBI-713738

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21905510

    Name: EBI-713738

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99816127042149705
    Non-specific binding CompPASS-Plus score: 1.8387057047142101E-3
    False-positive CompPASS-Plus score: 2.3873788708572499E-8

    10
    EBI-1044059
     logo
    YAP1
    YAP65
    Protein yorkie homolog

    [+1]
    Transcriptional coactivator YAP1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21905516

    Name: EBI-1044059

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21905516

    Name: EBI-1044059

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21905516

    Name: EBI-1044059

    Stoichiometry: 0.0

    F
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21905516

    Name: EBI-1044059

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21905516

    Name: EBI-1044059

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99948579534188597
    Non-specific binding CompPASS-Plus score: 5.1420426133122997E-4
    False-positive CompPASS-Plus score: 3.9678317889010999E-10

    11
    EBI-1384110
     logo
    TESK2
    Testicular protein kinase 2
    Dual specificity testis-specific protein kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21905522

    Name: EBI-1384110

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21905522

    Name: EBI-1384110

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21905522

    Name: EBI-1384110

    Stoichiometry: 0.0

    F
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21905522

    Name: EBI-1384110

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21905522

    Name: EBI-1384110

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999994147938798
    Non-specific binding CompPASS-Plus score: 5.8448719963614502E-8
    False-positive CompPASS-Plus score: 7.1891953004444603E-11

    12
    EBI-525456
     logo
    Insulin receptor substrate protein of 53 kDa
    Insulin receptor substrate p53/p58
    Fas ligand-associated factor 3

    [+1]
    Brain-specific angiogenesis inhibitor 1-associated protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21905528

    Name: EBI-525456

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21905528

    Name: EBI-525456

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21905528

    Name: EBI-525456

    Stoichiometry: 0.0

    F
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21905528

    Name: EBI-525456

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21905528

    Name: EBI-525456

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.999991091363022
    Non-specific binding CompPASS-Plus score: 8.9086369707822093E-6
    False-positive CompPASS-Plus score: 6.9652965603682999E-15

    13
    EBI-433642
     logo
    KIAA0894
    Ponsin
    c-Cbl-associated protein

    [+5]
    Sorbin and SH3 domain-containing protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Sorbin and SH3 domain-containing protein 1

    Participant: Sorbin and SH3 domain-containing protein 1

    Accession: EBI-21905534

    Name: EBI-433642

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Sorbin and SH3 domain-containing protein 1

    Participant: Sorbin and SH3 domain-containing protein 1

    Accession: EBI-21905534

    Name: EBI-433642

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Sorbin and SH3 domain-containing protein 1

    Participant: Sorbin and SH3 domain-containing protein 1

    Accession: EBI-21905534

    Name: EBI-433642

    Stoichiometry: 0.0

    F
    Participant: Sorbin and SH3 domain-containing protein 1

    Participant: Sorbin and SH3 domain-containing protein 1

    Accession: EBI-21905534

    Name: EBI-433642

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Sorbin and SH3 domain-containing protein 1

    Participant: Sorbin and SH3 domain-containing protein 1

    Accession: EBI-21905534

    Name: EBI-433642

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999963188399299
    Non-specific binding CompPASS-Plus score: 3.6192248307041301E-7
    False-positive CompPASS-Plus score: 6.1935243614207401E-9

    14
    EBI-746202
     logo
    Polo-like kinase 4
    Serine/threonine-protein kinase Sak
    Serine/threonine-protein kinase 18

    [+3]
    Serine/threonine-protein kinase PLK4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21905540

    Name: EBI-746202

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21905540

    Name: EBI-746202

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21905540

    Name: EBI-746202

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21905540

    Name: EBI-746202

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21905540

    Name: EBI-746202

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999994517099999
    Non-specific binding CompPASS-Plus score: 5.4682318579946302E-8
    False-positive CompPASS-Plus score: 1.46681531342822E-10

    15
    EBI-357393
     logo
    MAP3K2
    MAPKKK2
    MEKK2

    [+1]
    Mitogen-activated protein kinase kinase kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21905546

    Name: EBI-357393

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21905546

    Name: EBI-357393

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21905546

    Name: EBI-357393

    Stoichiometry: 0.0

    F
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21905546

    Name: EBI-357393

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21905546

    Name: EBI-357393

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999996531590096
    Non-specific binding CompPASS-Plus score: 3.4315357537650601E-8
    False-positive CompPASS-Plus score: 3.6874104467264603E-10

    16
    EBI-1644048
     logo
    KIF1C
    KIAA0706
    Kinesin-like protein KIF1C
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21905552

    Name: EBI-1644048

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21905552

    Name: EBI-1644048

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21905552

    Name: EBI-1644048

    Stoichiometry: 0.0

    F
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21905552

    Name: EBI-1644048

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21905552

    Name: EBI-1644048

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999031126298099
    Non-specific binding CompPASS-Plus score: 9.6886851086502205E-6
    False-positive CompPASS-Plus score: 5.1910299142479001E-11

    17
    EBI-353655
     logo
    FUSIP1
    TASR
    FUS-interacting serine-arginine-rich protein 1

    [+8]
    Serine/arginine-rich splicing factor 10
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/arginine-rich splicing factor 10

    Participant: Serine/arginine-rich splicing factor 10

    Accession: EBI-21905558

    Name: EBI-353655

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/arginine-rich splicing factor 10

    Participant: Serine/arginine-rich splicing factor 10

    Accession: EBI-21905558

    Name: EBI-353655

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/arginine-rich splicing factor 10

    Participant: Serine/arginine-rich splicing factor 10

    Accession: EBI-21905558

    Name: EBI-353655

    Stoichiometry: 0.0

    F
    Participant: Serine/arginine-rich splicing factor 10

    Participant: Serine/arginine-rich splicing factor 10

    Accession: EBI-21905558

    Name: EBI-353655

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/arginine-rich splicing factor 10

    Participant: Serine/arginine-rich splicing factor 10

    Accession: EBI-21905558

    Name: EBI-353655

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.86774351375877201
    Non-specific binding CompPASS-Plus score: 0.13225648623890099
    False-positive CompPASS-Plus score: 2.3270295220926198E-12

    18
    EBI-389845
     logo
    NCKAP1
    HEM2
    KIAA0587

    [+3]
    Nck-associated protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nck-associated protein 1

    Participant: Nck-associated protein 1

    Accession: EBI-21905564

    Name: EBI-389845

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Nck-associated protein 1

    Participant: Nck-associated protein 1

    Accession: EBI-21905564

    Name: EBI-389845

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nck-associated protein 1

    Participant: Nck-associated protein 1

    Accession: EBI-21905564

    Name: EBI-389845

    Stoichiometry: 0.0

    F
    Participant: Nck-associated protein 1

    Participant: Nck-associated protein 1

    Accession: EBI-21905564

    Name: EBI-389845

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nck-associated protein 1

    Participant: Nck-associated protein 1

    Accession: EBI-21905564

    Name: EBI-389845

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97029905016779305
    Non-specific binding CompPASS-Plus score: 2.9700949832194599E-2
    False-positive CompPASS-Plus score: 1.24862104439821E-14

    19
    EBI-6380719
     logo
    SRSF8
    SFRS2B
    SRP46

    [+2]
    Serine/arginine-rich splicing factor 8
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/arginine-rich splicing factor 8

    Participant: Serine/arginine-rich splicing factor 8

    Accession: EBI-21905570

    Name: EBI-6380719

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/arginine-rich splicing factor 8

    Participant: Serine/arginine-rich splicing factor 8

    Accession: EBI-21905570

    Name: EBI-6380719

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/arginine-rich splicing factor 8

    Participant: Serine/arginine-rich splicing factor 8

    Accession: EBI-21905570

    Name: EBI-6380719

    Stoichiometry: 0.0

    F
    Participant: Serine/arginine-rich splicing factor 8

    Participant: Serine/arginine-rich splicing factor 8

    Accession: EBI-21905570

    Name: EBI-6380719

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/arginine-rich splicing factor 8

    Participant: Serine/arginine-rich splicing factor 8

    Accession: EBI-21905570

    Name: EBI-6380719

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98323913284276299
    Non-specific binding CompPASS-Plus score: 1.6705777852846299E-2
    False-positive CompPASS-Plus score: 5.50893043909409E-5

    20
    EBI-359854
     logo
    YWHAQ
    14-3-3 protein tau
    14-3-3 protein T-cell

    [+1]
    14-3-3 protein theta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21905576

    Name: EBI-359854

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21905576

    Name: EBI-359854

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21905576

    Name: EBI-359854

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21905576

    Name: EBI-359854

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21905576

    Name: EBI-359854

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97907926180567595
    Non-specific binding CompPASS-Plus score: 2.0920738194322899E-2
    False-positive CompPASS-Plus score: 1.09052644982232E-15


    Graphical Representation of Experimental Features