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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 16429126

Journal: Nature (0028-0836)

Year of Publication: 2006

Title: Proteome survey reveals modularity of the yeast cell machinery.

Author List: Gavin AC., Aloy P., Grandi P., Krause R., Boesche M., Marzioch M., Rau C., Jensen LJ., Bastuck S., Dumpelfeld B., Edelmann A., Heurtier MA., Hoffman V., Hoefert C., Klein K., Hudak M., Michon AM., Schelder M., Schirle M., Remor M., Rudi T., Hooper S., Bauer A., Bouwmeester T., Casari G., Drewes G., Neubauer G., Rick JM., Kuster B., Bork P., Russell RB., Superti-Furga G.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Experiment (491 interactions)

Accession: EBI-765905

Name: gavin-2006-2

Host organism: Saccharomyces cerevisiae (Baker's yeast)

Organism: Saccharomyces cerevisiae (Baker's yeast)

Accession: EBI-140

Name: yeasx

Description: Saccharomyces cerevisiae (Baker's yeast)

Cross References:

Database
Identifier
Secondary identifier
Qualifier
yeast
-

Interaction Detection Method: inferred by author

Interaction detection method: inferred by author
Accession: EBI-608504

Name: inferred by author

Description: inferred by author

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0363
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Evidence based on the author of a paper assumption, either when the complete experimental support is not available or when the results are extended by homology to closely related orthologues sequences.


Participant Identification Method: predetermined

Participant identification method: predetermined
Accession: EBI-1465

Name: predetermined

Description: predetermined participant

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0396
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule whose sequence identity is not checked and has been assumed from external or previous experimental evidence(s).


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Supplemental Table 1
Tandem-Affinity-Purification coupled to mass Spectrometry (TAP/MS) of all 6 466 ORFs of Saccharomyces cerevisiae. The library with TAP tag cassettes at the 3' end of each ORF was created by homologous recombination. TAP-tagged proteins were purified with its interactors. A protein was considered identified if at least 5 different peptides were matched to the protein sequence. Proteins were identified with an average of 10 non-redundant matching peptides (range between 5 and 79).
Proteins were mapped to UniProtKB entries using the ordered-locus name given by the authors. Some ordered-locus names correspond to a common UniProtKB entry because ORFs had been merged . The locus history can be found on the SGD web site (http://www.yeastgenome.org/). Only the 1910 different purifications with at least one interactor -not including the bait- were recorded here. Proteins which were not found in the computed complexes have been annotated in Caution comments as they may represent non-specific binding.
complexes@embl.de
2005-12-14: RB Russell, Cellzome, Heidelberg, Germany.

Interaction

Accession: EBI-819830

Name: emp24-11

Description: complex 400 : Heteromeric p24 complex 1

Type: physical association

Interaction type: physical association
Accession: EBI-1813147

Name: physical association

Description: physical association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0915
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules within the same physical complex. Often identified under conditions which suggest that the molecules are in close proximity but not necessarily in direct contact with each other.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
C:endoplasmic reticulum
C:autophagic vacuole

Annotations:

Topic
Text
localization: endoplasmic reticulum, vacuole
The following proteins are considered as part of the core complex: ERP2 (YAL007C), ERP1 (YAR002C-A), EMP24 (YGL200C), ERV25 (YML012W)

Participants (12)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
1
EBI-6587
 logo
ERP2
FUN54
YAL007C
Protein ERP2
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Protein ERP2

Participant: Protein ERP2

Accession: EBI-819836

Name: EBI-6587

P
Participant: Protein ERP2

Participant: Protein ERP2

Accession: EBI-819836

Name: EBI-6587

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Protein ERP2

Participant: Protein ERP2

Accession: EBI-819836

Name: EBI-6587

Stoichiometry: 0.0

F
Participant: Protein ERP2

Participant: Protein ERP2

Accession: EBI-819836

Name: EBI-6587

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Protein ERP2

Participant: Protein ERP2

Accession: EBI-819836

Name: EBI-6587

Confidences:

Type
Value
No records found.

2
EBI-6581
 logo
ERP1
YAR002A
YAR002C-A
Protein ERP1
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Protein ERP1

Participant: Protein ERP1

Accession: EBI-819837

Name: EBI-6581

P
Participant: Protein ERP1

Participant: Protein ERP1

Accession: EBI-819837

Name: EBI-6581

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Protein ERP1

Participant: Protein ERP1

Accession: EBI-819837

Name: EBI-6581

Stoichiometry: 0.0

F
Participant: Protein ERP1

Participant: Protein ERP1

Accession: EBI-819837

Name: EBI-6581

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Protein ERP1

Participant: Protein ERP1

Accession: EBI-819837

Name: EBI-6581

Confidences:

Type
Value
No records found.

3
EBI-6593
 logo
ERP3
D2850
YDL018C
Protein ERP3
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Protein ERP3

Participant: Protein ERP3

Accession: EBI-819838

Name: EBI-6593

P
Participant: Protein ERP3

Participant: Protein ERP3

Accession: EBI-819838

Name: EBI-6593

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Protein ERP3

Participant: Protein ERP3

Accession: EBI-819838

Name: EBI-6593

Stoichiometry: 0.0

F
Participant: Protein ERP3

Participant: Protein ERP3

Accession: EBI-819838

Name: EBI-6593

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Protein ERP3

Participant: Protein ERP3

Accession: EBI-819838

Name: EBI-6593

Confidences:

Type
Value
No records found.

4
EBI-16002
 logo
RRP1
D4478
YDR087C
Ribosomal RNA-processing protein 1
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Ribosomal RNA-processing protein 1

Participant: Ribosomal RNA-processing protein 1

Accession: EBI-819839

Name: EBI-16002

P
Participant: Ribosomal RNA-processing protein 1

Participant: Ribosomal RNA-processing protein 1

Accession: EBI-819839

Name: EBI-16002

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Ribosomal RNA-processing protein 1

Participant: Ribosomal RNA-processing protein 1

Accession: EBI-819839

Name: EBI-16002

Stoichiometry: 0.0

F
Participant: Ribosomal RNA-processing protein 1

Participant: Ribosomal RNA-processing protein 1

Accession: EBI-819839

Name: EBI-16002

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Ribosomal RNA-processing protein 1

Participant: Ribosomal RNA-processing protein 1

Accession: EBI-819839

Name: EBI-16002

Confidences:

Type
Value
No records found.

5
EBI-13914
 logo
TBPY
TBY1
YGL048C

[+7]
26S proteasome regulatory subunit 8 homolog
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 26S proteasome regulatory subunit 8 homolog

Participant: 26S proteasome regulatory subunit 8 homolog

Accession: EBI-819840

Name: EBI-13914

P
Participant: 26S proteasome regulatory subunit 8 homolog

Participant: 26S proteasome regulatory subunit 8 homolog

Accession: EBI-819840

Name: EBI-13914

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 26S proteasome regulatory subunit 8 homolog

Participant: 26S proteasome regulatory subunit 8 homolog

Accession: EBI-819840

Name: EBI-13914

Stoichiometry: 0.0

F
Participant: 26S proteasome regulatory subunit 8 homolog

Participant: 26S proteasome regulatory subunit 8 homolog

Accession: EBI-819840

Name: EBI-13914

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: 26S proteasome regulatory subunit 8 homolog

Participant: 26S proteasome regulatory subunit 8 homolog

Accession: EBI-819840

Name: EBI-13914

Confidences:

Type
Value
No records found.

6
EBI-6431
 logo
EMP24
YGL200C
G1271

[+2]
Endosomal protein P24B
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Endosomal protein P24B

Participant: Endosomal protein P24B

Accession: EBI-819841

Name: EBI-6431

P
Participant: Endosomal protein P24B

Participant: Endosomal protein P24B

Accession: EBI-819841

Name: EBI-6431

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Endosomal protein P24B

Participant: Endosomal protein P24B

Accession: EBI-819841

Name: EBI-6431

Stoichiometry: 0.0

F
Participant: Endosomal protein P24B

Participant: Endosomal protein P24B

Accession: EBI-819841

Name: EBI-6431

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Endosomal protein P24B

Participant: Endosomal protein P24B

Accession: EBI-819841

Name: EBI-6431

Confidences:

Type
Value
No records found.

7
EBI-6603
 logo
ERP5
YHR110W
Protein ERP5
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Protein ERP5

Participant: Protein ERP5

Accession: EBI-819843

Name: EBI-6603

P
Participant: Protein ERP5

Participant: Protein ERP5

Accession: EBI-819843

Name: EBI-6603

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Protein ERP5

Participant: Protein ERP5

Accession: EBI-819843

Name: EBI-6603

Stoichiometry: 0.0

F
Participant: Protein ERP5

Participant: Protein ERP5

Accession: EBI-819843

Name: EBI-6603

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Protein ERP5

Participant: Protein ERP5

Accession: EBI-819843

Name: EBI-6603

Confidences:

Type
Value
No records found.

8
EBI-12084
 logo
NMD5
YJR132W
J2112

[+2]
Nonsense-mediated mRNA decay protein 5
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Nonsense-mediated mRNA decay protein 5

Participant: Nonsense-mediated mRNA decay protein 5

Accession: EBI-819844

Name: EBI-12084

P
Participant: Nonsense-mediated mRNA decay protein 5

Participant: Nonsense-mediated mRNA decay protein 5

Accession: EBI-819844

Name: EBI-12084

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Nonsense-mediated mRNA decay protein 5

Participant: Nonsense-mediated mRNA decay protein 5

Accession: EBI-819844

Name: EBI-12084

Stoichiometry: 0.0

F
Participant: Nonsense-mediated mRNA decay protein 5

Participant: Nonsense-mediated mRNA decay protein 5

Accession: EBI-819844

Name: EBI-12084

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Nonsense-mediated mRNA decay protein 5

Participant: Nonsense-mediated mRNA decay protein 5

Accession: EBI-819844

Name: EBI-12084

Confidences:

Type
Value
No records found.

9
EBI-6642
 logo
ERV25
YM9571.06
YML012W
Endoplasmic reticulum vesicle protein 25
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Endoplasmic reticulum vesicle protein 25

Participant: Endoplasmic reticulum vesicle protein 25

Accession: EBI-819845

Name: EBI-6642

P
Participant: Endoplasmic reticulum vesicle protein 25

Participant: Endoplasmic reticulum vesicle protein 25

Accession: EBI-819845

Name: EBI-6642

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Endoplasmic reticulum vesicle protein 25

Participant: Endoplasmic reticulum vesicle protein 25

Accession: EBI-819845

Name: EBI-6642

Stoichiometry: 0.0

F
Participant: Endoplasmic reticulum vesicle protein 25

Participant: Endoplasmic reticulum vesicle protein 25

Accession: EBI-819845

Name: EBI-6642

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Endoplasmic reticulum vesicle protein 25

Participant: Endoplasmic reticulum vesicle protein 25

Accession: EBI-819845

Name: EBI-6642

Confidences:

Type
Value
No records found.

10
EBI-18981
 logo
YM7056.02C
YML124C
TUB3
Tubulin alpha-3 chain
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Tubulin alpha-3 chain

Participant: Tubulin alpha-3 chain

Accession: EBI-819846

Name: EBI-18981

P
Participant: Tubulin alpha-3 chain

Participant: Tubulin alpha-3 chain

Accession: EBI-819846

Name: EBI-18981

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Tubulin alpha-3 chain

Participant: Tubulin alpha-3 chain

Accession: EBI-819846

Name: EBI-18981

Stoichiometry: 0.0

F
Participant: Tubulin alpha-3 chain

Participant: Tubulin alpha-3 chain

Accession: EBI-819846

Name: EBI-18981

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Tubulin alpha-3 chain

Participant: Tubulin alpha-3 chain

Accession: EBI-819846

Name: EBI-18981

Confidences:

Type
Value
No records found.

11
EBI-18520
 logo
RPT4
CRL13
PCS1

[+4]
26S proteasome subunit RPT4
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 26S proteasome subunit RPT4

Participant: 26S proteasome subunit RPT4

Accession: EBI-819847

Name: EBI-18520

P
Participant: 26S proteasome subunit RPT4

Participant: 26S proteasome subunit RPT4

Accession: EBI-819847

Name: EBI-18520

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 26S proteasome subunit RPT4

Participant: 26S proteasome subunit RPT4

Accession: EBI-819847

Name: EBI-18520

Stoichiometry: 0.0

F
Participant: 26S proteasome subunit RPT4

Participant: 26S proteasome subunit RPT4

Accession: EBI-819847

Name: EBI-18520

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: 26S proteasome subunit RPT4

Participant: 26S proteasome subunit RPT4

Accession: EBI-819847

Name: EBI-18520

Confidences:

Type
Value
No records found.

12
EBI-783263
 logo
RPL11B
RP39B
RPL16B

[+5]
60S ribosomal protein L11-B
Saccharomyces cerevisiae
Organism Details

Accession: EBI-2935809

Name: yeast

Description: Saccharomyces cerevisiae

Cross References:

Database
Identifier
Secondary identifier
Qualifier
baker's yeast

Expressed In Details

Accession:

Name:

-
neutral component
Experimental role: neutral component
Accession: EBI-55

Name: neutral component

Description: neutral component

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0497
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule role in an experimental setting that does not have an embedded asymmetry.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 60S ribosomal protein L11-B

Participant: 60S ribosomal protein L11-B

Accession: EBI-821285

Name: EBI-783263

P
Participant: 60S ribosomal protein L11-B

Participant: 60S ribosomal protein L11-B

Accession: EBI-821285

Name: EBI-783263

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 60S ribosomal protein L11-B

Participant: 60S ribosomal protein L11-B

Accession: EBI-821285

Name: EBI-783263

Stoichiometry: 0.0

F
Participant: 60S ribosomal protein L11-B

Participant: 60S ribosomal protein L11-B

Accession: EBI-821285

Name: EBI-783263

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: 60S ribosomal protein L11-B

Participant: 60S ribosomal protein L11-B

Accession: EBI-821285

Name: EBI-783263

Confidences:

Type
Value
No records found.