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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 22623428

Journal: Proteomics (1615-9853)

Year of Publication: 2012

Title: Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

Author List: Byron A., Humphries J.D., Craig S.E., Knight D., Humphries M.J.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Experiment (6 interactions)

Accession: EBI-6189904

Name: byron-2012-2

Host organism: In vitro

Organism: In vitro

Accession: EBI-1318

Name: in vitro

Description: In vitro

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
�Host Organism' is in vitro on experiments when one of the interacting proteins is extracellular or has an extracellular domain that participates in the interaction and /or the interaction is shown to occur in a tube.
The term is also used to indicate in vitro produced protein e.g. by coupled in vitro transcription translation system.
1. Interaction between a cellsurface receptor and a labelled purified protein ligand; 2. Two cells each of which express cellsurface molecules and are demonstrated to interact; 3. One cell expressing two or more cellsurface molecules which are demonstrated to interact.

Interaction Detection Method: crosslink

Interaction detection method: crosslink
Accession: EBI-1049

Name: crosslink

Description: cross-linking study

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0030
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Analysis of complexes obtained by input of energy or chemical treatments, or by introducing cysteines followed by oxidation to promote the formation of covalent bonds among molecules in close proximity.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
martin.humphries@manchester.ac.uk
imex curation
Only protein-protein interactions
-
The bait is captured on a protein A column via a Fc Igg tag and then exposed to the lysate containing the preys and to the action of dimethyl-3,3'-dithiobispropionimidate as crosslinking agent.
Different constructs of integrin alpha 4 are used (WT, X4C0 and alpha-4P alpha-5L).
Interactions involving 40S ribosomal protein S17 were not included because their sequences map to two different UniProt entries. Interactions involving Histone H2A type 1 were not included because their sequences map to two different UniProt entries and because the precise isoform involved could not be identified.

Interaction

Accession: EBI-6191076

Name: vcam1-chim

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Annotations:

Topic
Text
table S3
These interaction were detected using a lysate of K562 cells transfected with a chimera of the beta-propeller domain of alpha-4 integrin (Thr1-Leu440) and the leg, transmembrane and cytosolic domains of alpha-5 integrin (Thr459-ala1008).

Participants (454)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12345678910pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12345678910pp
1
EBI-6189824
 logo
VCAM1
INCAM-100
Vascular cell adhesion protein 1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Chlorocebus aethiops COS-1 cells
Expressed In Details

Accession: EBI-307641

Name: chlae-cos_1

Description: Chlorocebus aethiops COS-1 cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
green monkey

bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Vascular cell adhesion protein 1

Participant: Vascular cell adhesion protein 1

Accession: EBI-6191079

Name: EBI-6189824

P
Participant: Vascular cell adhesion protein 1

Participant: Vascular cell adhesion protein 1

Accession: EBI-6191079

Name: EBI-6189824

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Vascular cell adhesion protein 1

Participant: Vascular cell adhesion protein 1

Accession: EBI-6191079

Name: EBI-6189824

Stoichiometry: 0.0

F
Participant: Vascular cell adhesion protein 1

Participant: Vascular cell adhesion protein 1

Accession: EBI-6191079

Name: EBI-6189824

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
fc-igg tag
  • c-c
  • A
    Feature: EBI-6191080

    Feature: fc-igg tag

    Accession: EBI-6191080

    Name: fc-igg tag


    C
    Participant: Vascular cell adhesion protein 1

    Participant: Vascular cell adhesion protein 1

    Accession: EBI-6191079

    Name: EBI-6189824

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-358607
     logo
    EEF1D
    EF1D
    Antigen NY-CO-4
    Elongation factor 1-delta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Elongation factor 1-delta

    Participant: Elongation factor 1-delta

    Accession: EBI-6191870

    Name: EBI-358607

    P
    Participant: Elongation factor 1-delta

    Participant: Elongation factor 1-delta

    Accession: EBI-6191870

    Name: EBI-358607

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Elongation factor 1-delta

    Participant: Elongation factor 1-delta

    Accession: EBI-6191870

    Name: EBI-358607

    Stoichiometry: 0.0

    F
    Participant: Elongation factor 1-delta

    Participant: Elongation factor 1-delta

    Accession: EBI-6191870

    Name: EBI-358607

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Elongation factor 1-delta

    Participant: Elongation factor 1-delta

    Accession: EBI-6191870

    Name: EBI-358607

    Confidences:

    Type
    Value
    No records found.

    3
    EBI-1054499
     logo
    URCC3
    Translocase of outer membrane 34 kDa subunit
    TOMM34
    Mitochondrial import receptor subunit TOM34
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Mitochondrial import receptor subunit TOM34

    Participant: Mitochondrial import receptor subunit TOM34

    Accession: EBI-6191871

    Name: EBI-1054499

    P
    Participant: Mitochondrial import receptor subunit TOM34

    Participant: Mitochondrial import receptor subunit TOM34

    Accession: EBI-6191871

    Name: EBI-1054499

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Mitochondrial import receptor subunit TOM34

    Participant: Mitochondrial import receptor subunit TOM34

    Accession: EBI-6191871

    Name: EBI-1054499

    Stoichiometry: 0.0

    F
    Participant: Mitochondrial import receptor subunit TOM34

    Participant: Mitochondrial import receptor subunit TOM34

    Accession: EBI-6191871

    Name: EBI-1054499

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Mitochondrial import receptor subunit TOM34

    Participant: Mitochondrial import receptor subunit TOM34

    Accession: EBI-6191871

    Name: EBI-1054499

    Confidences:

    Type
    Value
    No records found.

    4
    EBI-346930
     logo
    PIK3R2
    Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta
    Phosphatidylinositol 3-kinase regulatory subunit beta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Accession: EBI-6191872

    Name: EBI-346930

    P
    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Accession: EBI-6191872

    Name: EBI-346930

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Accession: EBI-6191872

    Name: EBI-346930

    Stoichiometry: 0.0

    F
    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Accession: EBI-6191872

    Name: EBI-346930

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Participant: Phosphatidylinositol 3-kinase regulatory subunit beta

    Accession: EBI-6191872

    Name: EBI-346930

    Confidences:

    Type
    Value
    No records found.

    5
    EBI-357046
     logo
    CCT7
    CCTH
    NIP7-1

    [+2]
    T-complex protein 1 subunit eta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: T-complex protein 1 subunit eta

    Participant: T-complex protein 1 subunit eta

    Accession: EBI-6191873

    Name: EBI-357046

    P
    Participant: T-complex protein 1 subunit eta

    Participant: T-complex protein 1 subunit eta

    Accession: EBI-6191873

    Name: EBI-357046

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: T-complex protein 1 subunit eta

    Participant: T-complex protein 1 subunit eta

    Accession: EBI-6191873

    Name: EBI-357046

    Stoichiometry: 0.0

    F
    Participant: T-complex protein 1 subunit eta

    Participant: T-complex protein 1 subunit eta

    Accession: EBI-6191873

    Name: EBI-357046

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: T-complex protein 1 subunit eta

    Participant: T-complex protein 1 subunit eta

    Accession: EBI-6191873

    Name: EBI-357046

    Confidences:

    Type
    Value
    No records found.

    6
    EBI-1048247
     logo
    TBC1D15
    GTPase-activating protein RAB7
    TBC1 domain family member 15
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: TBC1 domain family member 15

    Participant: TBC1 domain family member 15

    Accession: EBI-6191874

    Name: EBI-1048247

    P
    Participant: TBC1 domain family member 15

    Participant: TBC1 domain family member 15

    Accession: EBI-6191874

    Name: EBI-1048247

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: TBC1 domain family member 15

    Participant: TBC1 domain family member 15

    Accession: EBI-6191874

    Name: EBI-1048247

    Stoichiometry: 0.0

    F
    Participant: TBC1 domain family member 15

    Participant: TBC1 domain family member 15

    Accession: EBI-6191874

    Name: EBI-1048247

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: TBC1 domain family member 15

    Participant: TBC1 domain family member 15

    Accession: EBI-6191874

    Name: EBI-1048247

    Confidences:

    Type
    Value
    No records found.

    7
    EBI-1053892
     logo
    ZBP1
    IGF-II mRNA-binding protein 1
    Coding region determinant-binding protein

    [+5]
    Insulin-like growth factor 2 mRNA-binding protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Accession: EBI-6191875

    Name: EBI-1053892

    P
    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Accession: EBI-6191875

    Name: EBI-1053892

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Accession: EBI-6191875

    Name: EBI-1053892

    Stoichiometry: 0.0

    F
    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Accession: EBI-6191875

    Name: EBI-1053892

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Participant: Insulin-like growth factor 2 mRNA-binding protein 1

    Accession: EBI-6191875

    Name: EBI-1053892

    Confidences:

    Type
    Value
    No records found.

    8
    EBI-2270000
     logo
    ATP5K
    ATP5ME
    ATP5I

    [+1]
    ATP synthase subunit e, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: ATP synthase subunit e, mitochondrial

    Participant: ATP synthase subunit e, mitochondrial

    Accession: EBI-6191876

    Name: EBI-2270000

    P
    Participant: ATP synthase subunit e, mitochondrial

    Participant: ATP synthase subunit e, mitochondrial

    Accession: EBI-6191876

    Name: EBI-2270000

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: ATP synthase subunit e, mitochondrial

    Participant: ATP synthase subunit e, mitochondrial

    Accession: EBI-6191876

    Name: EBI-2270000

    Stoichiometry: 0.0

    F
    Participant: ATP synthase subunit e, mitochondrial

    Participant: ATP synthase subunit e, mitochondrial

    Accession: EBI-6191876

    Name: EBI-2270000

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: ATP synthase subunit e, mitochondrial

    Participant: ATP synthase subunit e, mitochondrial

    Accession: EBI-6191876

    Name: EBI-2270000

    Confidences:

    Type
    Value
    No records found.

    9
    EBI-5279755
     logo
    CHD4
    ATP-dependent helicase CHD4
    Mi-2 autoantigen 218 kDa protein

    [+1]
    Chromodomain-helicase-DNA-binding protein 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Chromodomain-helicase-DNA-binding protein 4

    Participant: Chromodomain-helicase-DNA-binding protein 4

    Accession: EBI-6191877

    Name: EBI-5279755

    P
    Participant: Chromodomain-helicase-DNA-binding protein 4

    Participant: Chromodomain-helicase-DNA-binding protein 4

    Accession: EBI-6191877

    Name: EBI-5279755

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Chromodomain-helicase-DNA-binding protein 4

    Participant: Chromodomain-helicase-DNA-binding protein 4

    Accession: EBI-6191877

    Name: EBI-5279755

    Stoichiometry: 0.0

    F
    Participant: Chromodomain-helicase-DNA-binding protein 4

    Participant: Chromodomain-helicase-DNA-binding protein 4

    Accession: EBI-6191877

    Name: EBI-5279755

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Chromodomain-helicase-DNA-binding protein 4

    Participant: Chromodomain-helicase-DNA-binding protein 4

    Accession: EBI-6191877

    Name: EBI-5279755

    Confidences:

    Type
    Value
    No records found.

    10
    EBI-398920
     logo
    SFRS1
    Splicing factor, arginine/serine-rich 1
    SF2

    [+6]
    Serine/arginine-rich splicing factor 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/arginine-rich splicing factor 1

    Participant: Serine/arginine-rich splicing factor 1

    Accession: EBI-6191878

    Name: EBI-398920

    P
    Participant: Serine/arginine-rich splicing factor 1

    Participant: Serine/arginine-rich splicing factor 1

    Accession: EBI-6191878

    Name: EBI-398920

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/arginine-rich splicing factor 1

    Participant: Serine/arginine-rich splicing factor 1

    Accession: EBI-6191878

    Name: EBI-398920

    Stoichiometry: 0.0

    F
    Participant: Serine/arginine-rich splicing factor 1

    Participant: Serine/arginine-rich splicing factor 1

    Accession: EBI-6191878

    Name: EBI-398920

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/arginine-rich splicing factor 1

    Participant: Serine/arginine-rich splicing factor 1

    Accession: EBI-6191878

    Name: EBI-398920

    Confidences:

    Type
    Value
    No records found.

    11
    EBI-353580
     logo
    ACTR2
    ARP2
    Actin-like protein 2
    Actin-related protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Actin-related protein 2

    Participant: Actin-related protein 2

    Accession: EBI-6191879

    Name: EBI-353580

    P
    Participant: Actin-related protein 2

    Participant: Actin-related protein 2

    Accession: EBI-6191879

    Name: EBI-353580

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Actin-related protein 2

    Participant: Actin-related protein 2

    Accession: EBI-6191879

    Name: EBI-353580

    Stoichiometry: 0.0

    F
    Participant: Actin-related protein 2

    Participant: Actin-related protein 2

    Accession: EBI-6191879

    Name: EBI-353580

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Actin-related protein 2

    Participant: Actin-related protein 2

    Accession: EBI-6191879

    Name: EBI-353580

    Confidences:

    Type
    Value
    No records found.

    12
    EBI-400434
     logo
    FUS
    TLS
    Oncogene FUS

    [+4]
    RNA-binding protein FUS
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: RNA-binding protein FUS

    Participant: RNA-binding protein FUS

    Accession: EBI-6191880

    Name: EBI-400434

    P
    Participant: RNA-binding protein FUS

    Participant: RNA-binding protein FUS

    Accession: EBI-6191880

    Name: EBI-400434

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: RNA-binding protein FUS

    Participant: RNA-binding protein FUS

    Accession: EBI-6191880

    Name: EBI-400434

    Stoichiometry: 0.0

    F
    Participant: RNA-binding protein FUS

    Participant: RNA-binding protein FUS

    Accession: EBI-6191880

    Name: EBI-400434

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: RNA-binding protein FUS

    Participant: RNA-binding protein FUS

    Accession: EBI-6191880

    Name: EBI-400434

    Confidences:

    Type
    Value
    No records found.

    13
    EBI-351257
     logo
    DDX6
    HLR2
    RCK

    [+3]
    Probable ATP-dependent RNA helicase DDX6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Probable ATP-dependent RNA helicase DDX6

    Participant: Probable ATP-dependent RNA helicase DDX6

    Accession: EBI-6191881

    Name: EBI-351257

    P
    Participant: Probable ATP-dependent RNA helicase DDX6

    Participant: Probable ATP-dependent RNA helicase DDX6

    Accession: EBI-6191881

    Name: EBI-351257

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Probable ATP-dependent RNA helicase DDX6

    Participant: Probable ATP-dependent RNA helicase DDX6

    Accession: EBI-6191881

    Name: EBI-351257

    Stoichiometry: 0.0

    F
    Participant: Probable ATP-dependent RNA helicase DDX6

    Participant: Probable ATP-dependent RNA helicase DDX6

    Accession: EBI-6191881

    Name: EBI-351257

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Probable ATP-dependent RNA helicase DDX6

    Participant: Probable ATP-dependent RNA helicase DDX6

    Accession: EBI-6191881

    Name: EBI-351257

    Confidences:

    Type
    Value
    No records found.

    14
    EBI-353779
     logo
    DDX3X
    DBX
    DDX3

    [+3]
    ATP-dependent RNA helicase DDX3X
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: ATP-dependent RNA helicase DDX3X

    Participant: ATP-dependent RNA helicase DDX3X

    Accession: EBI-6191882

    Name: EBI-353779

    P
    Participant: ATP-dependent RNA helicase DDX3X

    Participant: ATP-dependent RNA helicase DDX3X

    Accession: EBI-6191882

    Name: EBI-353779

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: ATP-dependent RNA helicase DDX3X

    Participant: ATP-dependent RNA helicase DDX3X

    Accession: EBI-6191882

    Name: EBI-353779

    Stoichiometry: 0.0

    F
    Participant: ATP-dependent RNA helicase DDX3X

    Participant: ATP-dependent RNA helicase DDX3X

    Accession: EBI-6191882

    Name: EBI-353779

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: ATP-dependent RNA helicase DDX3X

    Participant: ATP-dependent RNA helicase DDX3X

    Accession: EBI-6191882

    Name: EBI-353779

    Confidences:

    Type
    Value
    No records found.

    15
    EBI-1047359
     logo
    G3BP1
    G3BP
    ATP-dependent DNA helicase VIII

    [+1]
    Ras GTPase-activating protein-binding protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ras GTPase-activating protein-binding protein 1

    Participant: Ras GTPase-activating protein-binding protein 1

    Accession: EBI-6191883

    Name: EBI-1047359

    P
    Participant: Ras GTPase-activating protein-binding protein 1

    Participant: Ras GTPase-activating protein-binding protein 1

    Accession: EBI-6191883

    Name: EBI-1047359

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Ras GTPase-activating protein-binding protein 1

    Participant: Ras GTPase-activating protein-binding protein 1

    Accession: EBI-6191883

    Name: EBI-1047359

    Stoichiometry: 0.0

    F
    Participant: Ras GTPase-activating protein-binding protein 1

    Participant: Ras GTPase-activating protein-binding protein 1

    Accession: EBI-6191883

    Name: EBI-1047359

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ras GTPase-activating protein-binding protein 1

    Participant: Ras GTPase-activating protein-binding protein 1

    Accession: EBI-6191883

    Name: EBI-1047359

    Confidences:

    Type
    Value
    No records found.

    16
    EBI-352939
     logo
    RUVBL2
    TIP48
    TIP49B

    [+8]
    RuvB-like 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: RuvB-like 2

    Participant: RuvB-like 2

    Accession: EBI-6191884

    Name: EBI-352939

    P
    Participant: RuvB-like 2

    Participant: RuvB-like 2

    Accession: EBI-6191884

    Name: EBI-352939

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: RuvB-like 2

    Participant: RuvB-like 2

    Accession: EBI-6191884

    Name: EBI-352939

    Stoichiometry: 0.0

    F
    Participant: RuvB-like 2

    Participant: RuvB-like 2

    Accession: EBI-6191884

    Name: EBI-352939

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: RuvB-like 2

    Participant: RuvB-like 2

    Accession: EBI-6191884

    Name: EBI-352939

    Confidences:

    Type
    Value
    No records found.

    17
    EBI-359410
     logo
    MCM5
    CDC46
    CDC46 homolog

    [+1]
    DNA replication licensing factor MCM5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication licensing factor MCM5

    Participant: DNA replication licensing factor MCM5

    Accession: EBI-6191885

    Name: EBI-359410

    P
    Participant: DNA replication licensing factor MCM5

    Participant: DNA replication licensing factor MCM5

    Accession: EBI-6191885

    Name: EBI-359410

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication licensing factor MCM5

    Participant: DNA replication licensing factor MCM5

    Accession: EBI-6191885

    Name: EBI-359410

    Stoichiometry: 0.0

    F
    Participant: DNA replication licensing factor MCM5

    Participant: DNA replication licensing factor MCM5

    Accession: EBI-6191885

    Name: EBI-359410

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication licensing factor MCM5

    Participant: DNA replication licensing factor MCM5

    Accession: EBI-6191885

    Name: EBI-359410

    Confidences:

    Type
    Value
    No records found.

    18
    EBI-356410
     logo
    KRT16
    KRT16A
    Keratin-16

    [+1]
    Keratin, type I cytoskeletal 16
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Keratin, type I cytoskeletal 16

    Participant: Keratin, type I cytoskeletal 16

    Accession: EBI-6191886

    Name: EBI-356410

    P
    Participant: Keratin, type I cytoskeletal 16

    Participant: Keratin, type I cytoskeletal 16

    Accession: EBI-6191886

    Name: EBI-356410

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Keratin, type I cytoskeletal 16

    Participant: Keratin, type I cytoskeletal 16

    Accession: EBI-6191886

    Name: EBI-356410

    Stoichiometry: 0.0

    F
    Participant: Keratin, type I cytoskeletal 16

    Participant: Keratin, type I cytoskeletal 16

    Accession: EBI-6191886

    Name: EBI-356410

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Keratin, type I cytoskeletal 16

    Participant: Keratin, type I cytoskeletal 16

    Accession: EBI-6191886

    Name: EBI-356410

    Confidences:

    Type
    Value
    No records found.

    19
    EBI-1042703
     logo
    NUP93
    KIAA0095
    Nucleoporin Nup93

    [+1]
    Nuclear pore complex protein Nup93
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear pore complex protein Nup93

    Participant: Nuclear pore complex protein Nup93

    Accession: EBI-6191887

    Name: EBI-1042703

    P
    Participant: Nuclear pore complex protein Nup93

    Participant: Nuclear pore complex protein Nup93

    Accession: EBI-6191887

    Name: EBI-1042703

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nuclear pore complex protein Nup93

    Participant: Nuclear pore complex protein Nup93

    Accession: EBI-6191887

    Name: EBI-1042703

    Stoichiometry: 0.0

    F
    Participant: Nuclear pore complex protein Nup93

    Participant: Nuclear pore complex protein Nup93

    Accession: EBI-6191887

    Name: EBI-1042703

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear pore complex protein Nup93

    Participant: Nuclear pore complex protein Nup93

    Accession: EBI-6191887

    Name: EBI-1042703

    Confidences:

    Type
    Value
    No records found.

    20
    EBI-359733
     logo
    26S proteasome regulatory subunit RPN5
    PSMD12
    26S proteasome regulatory subunit p55
    26S proteasome non-ATPase regulatory subunit 12
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Homo sapiens myeloid leukemia cells.
    Expressed In Details

    Accession: EBI-307659

    Name: human-k_562

    Description: Homo sapiens myeloid leukemia cells.

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human
    -

    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Accession: EBI-6191888

    Name: EBI-359733

    P
    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Accession: EBI-6191888

    Name: EBI-359733

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Accession: EBI-6191888

    Name: EBI-359733

    Stoichiometry: 0.0

    F
    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Accession: EBI-6191888

    Name: EBI-359733

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Participant: 26S proteasome non-ATPase regulatory subunit 12

    Accession: EBI-6191888

    Name: EBI-359733

    Confidences:

    Type
    Value
    No records found.


    Graphical Representation of Experimental Features