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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 28514442

Journal: Nature

Year of Publication: 2017

Title: Architecture of the human interactome defines protein communities and disease networks.

Author List: Huttlin EL., Bruckner RJ., Paulo JA., Cannon JR., Ting L., Baltier K., Colby G., Gebreab F., Gygi MP., Parzen H., Szpyt J., Tam S., Zarraga G., Pontano-Vaites L., Swarup S., White AE., Schweppe DK., Rad R., Erickson BK., Obar RA., Guruharsha KG., Li K., Artavanis-Tsakonas S., Gygi SP., Harper JW.

Cross References:

Experiment (6 interactions)

Accession: EBI-21902672

Name: huttlin-2017-5

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
edward_huttlin@hms.harvard.edu,steven.gygi@hms.harvard.edu,wade_harper@hms.harvard.edu
imex curation

Interaction

Accession: EBI-21902679

Name: ywhaq-ablim1-1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Supplementary table 2 (14-3-3 sheet)

Participants (201)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12345678910pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12345678910pp
1
EBI-359854
 logo
14-3-3 protein tau
14-3-3 protein T-cell
Protein HS1

[+1]
14-3-3 protein theta
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 14-3-3 protein theta

Participant: 14-3-3 protein theta

Accession: EBI-21902681

Name: EBI-359854

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: 14-3-3 protein theta

Participant: 14-3-3 protein theta

Accession: EBI-21902681

Name: EBI-359854

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 14-3-3 protein theta

Participant: 14-3-3 protein theta

Accession: EBI-21902681

Name: EBI-359854

Stoichiometry: 0.0

F
Participant: 14-3-3 protein theta

Participant: 14-3-3 protein theta

Accession: EBI-21902681

Name: EBI-359854

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
C-terminal HA-flag tag
  • c-c
  • A
    Feature: EBI-21902683

    Feature: C-terminal HA-flag tag

    Accession: EBI-21902683

    Name: C-terminal HA-flag tag


    C
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-21902681

    Name: EBI-359854

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-8531039
     logo
    FOXO6
    Forkhead box protein O6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21902686

    Name: EBI-8531039

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21902686

    Name: EBI-8531039

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21902686

    Name: EBI-8531039

    Stoichiometry: 0.0

    F
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21902686

    Name: EBI-8531039

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Forkhead box protein O6

    Participant: Forkhead box protein O6

    Accession: EBI-21902686

    Name: EBI-8531039

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999625275364001
    Non-specific binding CompPASS-Plus score: 5.0894344235129698E-8
    False-positive CompPASS-Plus score: 3.6963520157604501E-6

    3
    EBI-715576
     logo
    Antigen NY-CO-9
    HDAC5
    KIAA0600
    Histone deacetylase 5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21902692

    Name: EBI-715576

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21902692

    Name: EBI-715576

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21902692

    Name: EBI-715576

    Stoichiometry: 0.0

    F
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21902692

    Name: EBI-715576

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Histone deacetylase 5

    Participant: Histone deacetylase 5

    Accession: EBI-21902692

    Name: EBI-715576

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99998267640566896
    Non-specific binding CompPASS-Plus score: 1.72903686212229E-5
    False-positive CompPASS-Plus score: 3.3225709431628203E-8

    4
    EBI-1046479
     logo
    MYCPBP
    DENN domain-containing protein 4A
    DENND4A

    [+1]
    C-myc promoter-binding protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21902698

    Name: EBI-1046479

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21902698

    Name: EBI-1046479

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21902698

    Name: EBI-1046479

    Stoichiometry: 0.0

    F
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21902698

    Name: EBI-1046479

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: C-myc promoter-binding protein

    Participant: C-myc promoter-binding protein

    Accession: EBI-21902698

    Name: EBI-1046479

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99998143940877904
    Non-specific binding CompPASS-Plus score: 1.8560572249738499E-5
    False-positive CompPASS-Plus score: 1.89712403337739E-11

    5
    EBI-21550113
     logo
    SPEG
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-21902704

    Name: EBI-21550113

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant:

    Participant:

    Accession: EBI-21902704

    Name: EBI-21550113

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant:

    Participant:

    Accession: EBI-21902704

    Name: EBI-21550113

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-21902704

    Name: EBI-21550113

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-21902704

    Name: EBI-21550113

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99997022721955098
    Non-specific binding CompPASS-Plus score: 1.6961067289045899E-5
    False-positive CompPASS-Plus score: 1.28117131602593E-5

    6
    EBI-713738
     logo
    KIAA1142
    p21-activated kinase 4
    PAK4
    Serine/threonine-protein kinase PAK 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21902710

    Name: EBI-713738

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21902710

    Name: EBI-713738

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21902710

    Name: EBI-713738

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21902710

    Name: EBI-713738

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase PAK 4

    Participant: Serine/threonine-protein kinase PAK 4

    Accession: EBI-21902710

    Name: EBI-713738

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97919029533402202
    Non-specific binding CompPASS-Plus score: 2.0809638561432999E-2
    False-positive CompPASS-Plus score: 6.6104545309305105E-8

    7
    EBI-1044059
     logo
    Protein yorkie homolog
    Yes-associated protein YAP65 homolog
    YAP1

    [+1]
    Transcriptional coactivator YAP1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21902716

    Name: EBI-1044059

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21902716

    Name: EBI-1044059

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21902716

    Name: EBI-1044059

    Stoichiometry: 0.0

    F
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21902716

    Name: EBI-1044059

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Transcriptional coactivator YAP1

    Participant: Transcriptional coactivator YAP1

    Accession: EBI-21902716

    Name: EBI-1044059

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99981374918271604
    Non-specific binding CompPASS-Plus score: 1.8625081463454699E-4
    False-positive CompPASS-Plus score: 2.6493671085090002E-12

    8
    EBI-1384110
     logo
    Testicular protein kinase 2
    TESK2
    Dual specificity testis-specific protein kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21902722

    Name: EBI-1384110

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21902722

    Name: EBI-1384110

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21902722

    Name: EBI-1384110

    Stoichiometry: 0.0

    F
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21902722

    Name: EBI-1384110

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity testis-specific protein kinase 2

    Participant: Dual specificity testis-specific protein kinase 2

    Accession: EBI-21902722

    Name: EBI-1384110

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99998607929315098
    Non-specific binding CompPASS-Plus score: 6.05029051549268E-6
    False-positive CompPASS-Plus score: 7.8704163335043598E-6

    9
    EBI-525456
     logo
    Insulin receptor substrate protein of 53 kDa
    Insulin receptor substrate p53/p58
    Fas ligand-associated factor 3

    [+1]
    Brain-specific angiogenesis inhibitor 1-associated protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21902728

    Name: EBI-525456

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21902728

    Name: EBI-525456

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21902728

    Name: EBI-525456

    Stoichiometry: 0.0

    F
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21902728

    Name: EBI-525456

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Participant: Brain-specific angiogenesis inhibitor 1-associated protein 2

    Accession: EBI-21902728

    Name: EBI-525456

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99993399379231995
    Non-specific binding CompPASS-Plus score: 6.6006207621704705E-5
    False-positive CompPASS-Plus score: 5.7932261827912097E-14

    10
    EBI-746202
     logo
    Polo-like kinase 4
    Serine/threonine-protein kinase Sak
    Serine/threonine-protein kinase 18

    [+3]
    Serine/threonine-protein kinase PLK4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21902734

    Name: EBI-746202

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21902734

    Name: EBI-746202

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21902734

    Name: EBI-746202

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21902734

    Name: EBI-746202

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase PLK4

    Participant: Serine/threonine-protein kinase PLK4

    Accession: EBI-21902734

    Name: EBI-746202

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999981453716003
    Non-specific binding CompPASS-Plus score: 1.62145897945636E-7
    False-positive CompPASS-Plus score: 2.3316941552702502E-8

    11
    EBI-357393
     logo
    MAPK/ERK kinase kinase 2
    MAP3K2
    MAPKKK2

    [+1]
    Mitogen-activated protein kinase kinase kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21902740

    Name: EBI-357393

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21902740

    Name: EBI-357393

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21902740

    Name: EBI-357393

    Stoichiometry: 0.0

    F
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21902740

    Name: EBI-357393

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Mitogen-activated protein kinase kinase kinase 2

    Participant: Mitogen-activated protein kinase kinase kinase 2

    Accession: EBI-21902740

    Name: EBI-357393

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999935286591002
    Non-specific binding CompPASS-Plus score: 2.5804977642469702E-7
    False-positive CompPASS-Plus score: 3.8908431366612001E-7

    12
    EBI-1644048
     logo
    KIF1C
    KIAA0706
    Kinesin-like protein KIF1C
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21902746

    Name: EBI-1644048

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21902746

    Name: EBI-1644048

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21902746

    Name: EBI-1644048

    Stoichiometry: 0.0

    F
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21902746

    Name: EBI-1644048

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kinesin-like protein KIF1C

    Participant: Kinesin-like protein KIF1C

    Accession: EBI-21902746

    Name: EBI-1644048

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99995990291532399
    Non-specific binding CompPASS-Plus score: 4.0096881996030102E-5
    False-positive CompPASS-Plus score: 2.0267986004491701E-10

    13
    EBI-927511
     logo
    ATP-dependent chromatin-remodeling protein
    Williams syndrome transcription factor-related chromatin-remodeling factor 180
    CHRAC subunit ACF1

    [+6]
    Bromodomain adjacent to zinc finger domain protein 1A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Accession: EBI-21902752

    Name: EBI-927511

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Accession: EBI-21902752

    Name: EBI-927511

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Accession: EBI-21902752

    Name: EBI-927511

    Stoichiometry: 0.0

    F
    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Accession: EBI-21902752

    Name: EBI-927511

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Participant: Bromodomain adjacent to zinc finger domain protein 1A

    Accession: EBI-21902752

    Name: EBI-927511

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99065359911459205
    Non-specific binding CompPASS-Plus score: 9.3456181481909005E-3
    False-positive CompPASS-Plus score: 7.8273721670101595E-7

    14
    EBI-1373806
     logo
    Protein kinase A-anchoring protein 13
    Breast cancer nuclear receptor-binding auxiliary protein
    Human thyroid-anchoring protein 31

    [+9]
    A-kinase anchor protein 13
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 13

    Participant: A-kinase anchor protein 13

    Accession: EBI-21902758

    Name: EBI-1373806

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 13

    Participant: A-kinase anchor protein 13

    Accession: EBI-21902758

    Name: EBI-1373806

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 13

    Participant: A-kinase anchor protein 13

    Accession: EBI-21902758

    Name: EBI-1373806

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 13

    Participant: A-kinase anchor protein 13

    Accession: EBI-21902758

    Name: EBI-1373806

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 13

    Participant: A-kinase anchor protein 13

    Accession: EBI-21902758

    Name: EBI-1373806

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999947600137595
    Non-specific binding CompPASS-Plus score: 5.2399545977510505E-7
    False-positive CompPASS-Plus score: 3.1638960955945298E-12

    15
    EBI-2556215
     logo
    GLCCI1
    Glucocorticoid-induced transcript 1 protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Glucocorticoid-induced transcript 1 protein

    Participant: Glucocorticoid-induced transcript 1 protein

    Accession: EBI-21902764

    Name: EBI-2556215

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Glucocorticoid-induced transcript 1 protein

    Participant: Glucocorticoid-induced transcript 1 protein

    Accession: EBI-21902764

    Name: EBI-2556215

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Glucocorticoid-induced transcript 1 protein

    Participant: Glucocorticoid-induced transcript 1 protein

    Accession: EBI-21902764

    Name: EBI-2556215

    Stoichiometry: 0.0

    F
    Participant: Glucocorticoid-induced transcript 1 protein

    Participant: Glucocorticoid-induced transcript 1 protein

    Accession: EBI-21902764

    Name: EBI-2556215

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Glucocorticoid-induced transcript 1 protein

    Participant: Glucocorticoid-induced transcript 1 protein

    Accession: EBI-21902764

    Name: EBI-2556215

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99969345124178899
    Non-specific binding CompPASS-Plus score: 2.5315592447883498E-4
    False-positive CompPASS-Plus score: 5.3392833731916899E-5

    16
    EBI-2372709
     logo
    OSBPL6
    ORP6
    Oxysterol-binding protein-related protein 6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Oxysterol-binding protein-related protein 6

    Participant: Oxysterol-binding protein-related protein 6

    Accession: EBI-21902770

    Name: EBI-2372709

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Oxysterol-binding protein-related protein 6

    Participant: Oxysterol-binding protein-related protein 6

    Accession: EBI-21902770

    Name: EBI-2372709

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Oxysterol-binding protein-related protein 6

    Participant: Oxysterol-binding protein-related protein 6

    Accession: EBI-21902770

    Name: EBI-2372709

    Stoichiometry: 0.0

    F
    Participant: Oxysterol-binding protein-related protein 6

    Participant: Oxysterol-binding protein-related protein 6

    Accession: EBI-21902770

    Name: EBI-2372709

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Oxysterol-binding protein-related protein 6

    Participant: Oxysterol-binding protein-related protein 6

    Accession: EBI-21902770

    Name: EBI-2372709

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98998109179085703
    Non-specific binding CompPASS-Plus score: 1.00189078809236E-2
    False-positive CompPASS-Plus score: 3.2821957601184501E-10

    17
    EBI-21360273
     logo
    AGAP1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-21902776

    Name: EBI-21360273

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant:

    Participant:

    Accession: EBI-21902776

    Name: EBI-21360273

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant:

    Participant:

    Accession: EBI-21902776

    Name: EBI-21360273

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-21902776

    Name: EBI-21360273

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-21902776

    Name: EBI-21360273

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.95368068616963297
    Non-specific binding CompPASS-Plus score: 4.1857526487074099E-3
    False-positive CompPASS-Plus score: 4.2133561181659701E-2

    18
    EBI-750020
     logo
    CDC-like kinase 2
    CLK2
    Dual specificity protein kinase CLK2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity protein kinase CLK2

    Participant: Dual specificity protein kinase CLK2

    Accession: EBI-21902782

    Name: EBI-750020

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Dual specificity protein kinase CLK2

    Participant: Dual specificity protein kinase CLK2

    Accession: EBI-21902782

    Name: EBI-750020

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity protein kinase CLK2

    Participant: Dual specificity protein kinase CLK2

    Accession: EBI-21902782

    Name: EBI-750020

    Stoichiometry: 0.0

    F
    Participant: Dual specificity protein kinase CLK2

    Participant: Dual specificity protein kinase CLK2

    Accession: EBI-21902782

    Name: EBI-750020

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity protein kinase CLK2

    Participant: Dual specificity protein kinase CLK2

    Accession: EBI-21902782

    Name: EBI-750020

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.895547546965338
    Non-specific binding CompPASS-Plus score: 0.104452151065958
    False-positive CompPASS-Plus score: 3.0196870345084398E-7

    19
    EBI-745579
     logo
    CDC-like kinase 3
    CLK3
    Dual specificity protein kinase CLK3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity protein kinase CLK3

    Participant: Dual specificity protein kinase CLK3

    Accession: EBI-21902788

    Name: EBI-745579

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Dual specificity protein kinase CLK3

    Participant: Dual specificity protein kinase CLK3

    Accession: EBI-21902788

    Name: EBI-745579

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity protein kinase CLK3

    Participant: Dual specificity protein kinase CLK3

    Accession: EBI-21902788

    Name: EBI-745579

    Stoichiometry: 0.0

    F
    Participant: Dual specificity protein kinase CLK3

    Participant: Dual specificity protein kinase CLK3

    Accession: EBI-21902788

    Name: EBI-745579

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity protein kinase CLK3

    Participant: Dual specificity protein kinase CLK3

    Accession: EBI-21902788

    Name: EBI-745579

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99719615703251596
    Non-specific binding CompPASS-Plus score: 2.8038429494564401E-3
    False-positive CompPASS-Plus score: 1.8027320263400801E-11

    20
    EBI-741729
     logo
    Willin
    FRMD6
    C14orf31
    FERM domain-containing protein 6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: FERM domain-containing protein 6

    Participant: FERM domain-containing protein 6

    Accession: EBI-21902794

    Name: EBI-741729

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: FERM domain-containing protein 6

    Participant: FERM domain-containing protein 6

    Accession: EBI-21902794

    Name: EBI-741729

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: FERM domain-containing protein 6

    Participant: FERM domain-containing protein 6

    Accession: EBI-21902794

    Name: EBI-741729

    Stoichiometry: 0.0

    F
    Participant: FERM domain-containing protein 6

    Participant: FERM domain-containing protein 6

    Accession: EBI-21902794

    Name: EBI-741729

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: FERM domain-containing protein 6

    Participant: FERM domain-containing protein 6

    Accession: EBI-21902794

    Name: EBI-741729

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999240760920605
    Non-specific binding CompPASS-Plus score: 7.5685599163888996E-6
    False-positive CompPASS-Plus score: 2.38308781211579E-8


    Graphical Representation of Experimental Features