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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 28514442

Journal: Nature

Year of Publication: 2017

Title: Architecture of the human interactome defines protein communities and disease networks.

Author List: Huttlin EL., Bruckner RJ., Paulo JA., Cannon JR., Ting L., Baltier K., Colby G., Gebreab F., Gygi MP., Parzen H., Szpyt J., Tam S., Zarraga G., Pontano-Vaites L., Swarup S., White AE., Schweppe DK., Rad R., Erickson BK., Obar RA., Guruharsha KG., Li K., Artavanis-Tsakonas S., Gygi SP., Harper JW.

Cross References:

Experiment (5110 interactions)

Accession: EBI-21498811

Name: huttlin-2017-3

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
Experimental roles have been inferred upon counting participant occurrences and might not reflect the actual constructs used in the original experiments. Interactions depicted in this experiment may be an aggregate from different co-immunoprecipitations, using bait constructs that may or may not represent the full length sequence of the referenced protein.
edward_huttlin@hms.harvard.edu,steven.gygi@hms.harvard.edu,wade_harper@hms.harvard.edu
imex curation

Interaction

Accession: EBI-21839594

Name: ssrp1-csnk2a1-1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Supplementary table 1

Participants (17)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
1
EBI-353771
 logo
SSRP1
FACT80
Facilitates chromatin transcription complex subunit SSRP1

[+5]
FACT complex subunit SSRP1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: FACT complex subunit SSRP1

Participant: FACT complex subunit SSRP1

Accession: EBI-21839596

Name: EBI-353771

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: FACT complex subunit SSRP1

Participant: FACT complex subunit SSRP1

Accession: EBI-21839596

Name: EBI-353771

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: FACT complex subunit SSRP1

Participant: FACT complex subunit SSRP1

Accession: EBI-21839596

Name: EBI-353771

Stoichiometry: 0.0

F
Participant: FACT complex subunit SSRP1

Participant: FACT complex subunit SSRP1

Accession: EBI-21839596

Name: EBI-353771

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
C-terminal HA-flag tag
  • c-c
  • A
    Feature: EBI-21839598

    Feature: C-terminal HA-flag tag

    Accession: EBI-21839598

    Name: C-terminal HA-flag tag


    C
    Participant: FACT complex subunit SSRP1

    Participant: FACT complex subunit SSRP1

    Accession: EBI-21839596

    Name: EBI-353771

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-355676
     logo
    PARP1
    ADPRT
    PPOL

    [+5]
    Poly [ADP-ribose] polymerase 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Poly [ADP-ribose] polymerase 1

    Participant: Poly [ADP-ribose] polymerase 1

    Accession: EBI-21839601

    Name: EBI-355676

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Poly [ADP-ribose] polymerase 1

    Participant: Poly [ADP-ribose] polymerase 1

    Accession: EBI-21839601

    Name: EBI-355676

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Poly [ADP-ribose] polymerase 1

    Participant: Poly [ADP-ribose] polymerase 1

    Accession: EBI-21839601

    Name: EBI-355676

    Stoichiometry: 0.0

    F
    Participant: Poly [ADP-ribose] polymerase 1

    Participant: Poly [ADP-ribose] polymerase 1

    Accession: EBI-21839601

    Name: EBI-355676

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Poly [ADP-ribose] polymerase 1

    Participant: Poly [ADP-ribose] polymerase 1

    Accession: EBI-21839601

    Name: EBI-355676

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.83044951701162295
    Non-specific binding CompPASS-Plus score: 0.16955048298837599
    False-positive CompPASS-Plus score: 6.9293069972814598E-16

    3
    EBI-374938
     logo
    MCM4
    CDC21
    CDC21 homolog

    [+1]
    DNA replication licensing factor MCM4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication licensing factor MCM4

    Participant: DNA replication licensing factor MCM4

    Accession: EBI-21839607

    Name: EBI-374938

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA replication licensing factor MCM4

    Participant: DNA replication licensing factor MCM4

    Accession: EBI-21839607

    Name: EBI-374938

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication licensing factor MCM4

    Participant: DNA replication licensing factor MCM4

    Accession: EBI-21839607

    Name: EBI-374938

    Stoichiometry: 0.0

    F
    Participant: DNA replication licensing factor MCM4

    Participant: DNA replication licensing factor MCM4

    Accession: EBI-21839607

    Name: EBI-374938

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication licensing factor MCM4

    Participant: DNA replication licensing factor MCM4

    Accession: EBI-21839607

    Name: EBI-374938

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98993803782497403
    Non-specific binding CompPASS-Plus score: 1.00619621750246E-2
    False-positive CompPASS-Plus score: 9.4415295663667598E-16

    4
    EBI-355924
     logo
    MCM7
    CDC47
    MCM2

    [+2]
    DNA replication licensing factor MCM7
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication licensing factor MCM7

    Participant: DNA replication licensing factor MCM7

    Accession: EBI-21839613

    Name: EBI-355924

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA replication licensing factor MCM7

    Participant: DNA replication licensing factor MCM7

    Accession: EBI-21839613

    Name: EBI-355924

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication licensing factor MCM7

    Participant: DNA replication licensing factor MCM7

    Accession: EBI-21839613

    Name: EBI-355924

    Stoichiometry: 0.0

    F
    Participant: DNA replication licensing factor MCM7

    Participant: DNA replication licensing factor MCM7

    Accession: EBI-21839613

    Name: EBI-355924

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication licensing factor MCM7

    Participant: DNA replication licensing factor MCM7

    Accession: EBI-21839613

    Name: EBI-355924

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.84041006289714704
    Non-specific binding CompPASS-Plus score: 0.159589937102847
    False-positive CompPASS-Plus score: 6.2397055341118797E-15

    5
    EBI-374819
     logo
    MCM2
    BM28
    CDCL1

    [+4]
    DNA replication licensing factor MCM2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication licensing factor MCM2

    Participant: DNA replication licensing factor MCM2

    Accession: EBI-21839619

    Name: EBI-374819

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA replication licensing factor MCM2

    Participant: DNA replication licensing factor MCM2

    Accession: EBI-21839619

    Name: EBI-374819

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication licensing factor MCM2

    Participant: DNA replication licensing factor MCM2

    Accession: EBI-21839619

    Name: EBI-374819

    Stoichiometry: 0.0

    F
    Participant: DNA replication licensing factor MCM2

    Participant: DNA replication licensing factor MCM2

    Accession: EBI-21839619

    Name: EBI-374819

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication licensing factor MCM2

    Participant: DNA replication licensing factor MCM2

    Accession: EBI-21839619

    Name: EBI-374819

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.995231201366789
    Non-specific binding CompPASS-Plus score: 4.7687986331879798E-3
    False-positive CompPASS-Plus score: 2.3525318587811599E-14

    6
    EBI-347804
     logo
    CSNK2A1
    CK2A1
    Casein kinase II subunit alpha
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Casein kinase II subunit alpha

    Participant: Casein kinase II subunit alpha

    Accession: EBI-21839625

    Name: EBI-347804

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Casein kinase II subunit alpha

    Participant: Casein kinase II subunit alpha

    Accession: EBI-21839625

    Name: EBI-347804

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Casein kinase II subunit alpha

    Participant: Casein kinase II subunit alpha

    Accession: EBI-21839625

    Name: EBI-347804

    Stoichiometry: 0.0

    F
    Participant: Casein kinase II subunit alpha

    Participant: Casein kinase II subunit alpha

    Accession: EBI-21839625

    Name: EBI-347804

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Casein kinase II subunit alpha

    Participant: Casein kinase II subunit alpha

    Accession: EBI-21839625

    Name: EBI-347804

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.75373495279887104
    Non-specific binding CompPASS-Plus score: 0.246265047181285
    False-positive CompPASS-Plus score: 1.98429604357582E-11

    7
    EBI-372610
     logo
    Xeroderma pigmentosum group C-complementing protein
    p125
    XPC

    [+1]
    DNA repair protein complementing XP-C cells
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA repair protein complementing XP-C cells

    Participant: DNA repair protein complementing XP-C cells

    Accession: EBI-21839631

    Name: EBI-372610

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA repair protein complementing XP-C cells

    Participant: DNA repair protein complementing XP-C cells

    Accession: EBI-21839631

    Name: EBI-372610

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA repair protein complementing XP-C cells

    Participant: DNA repair protein complementing XP-C cells

    Accession: EBI-21839631

    Name: EBI-372610

    Stoichiometry: 0.0

    F
    Participant: DNA repair protein complementing XP-C cells

    Participant: DNA repair protein complementing XP-C cells

    Accession: EBI-21839631

    Name: EBI-372610

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA repair protein complementing XP-C cells

    Participant: DNA repair protein complementing XP-C cells

    Accession: EBI-21839631

    Name: EBI-372610

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99791967812680005
    Non-specific binding CompPASS-Plus score: 2.0803218731990998E-3
    False-positive CompPASS-Plus score: 2.1935089906066999E-22

    8
    EBI-374900
     logo
    MCM6
    p105MCM
    DNA replication licensing factor MCM6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication licensing factor MCM6

    Participant: DNA replication licensing factor MCM6

    Accession: EBI-21839637

    Name: EBI-374900

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA replication licensing factor MCM6

    Participant: DNA replication licensing factor MCM6

    Accession: EBI-21839637

    Name: EBI-374900

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication licensing factor MCM6

    Participant: DNA replication licensing factor MCM6

    Accession: EBI-21839637

    Name: EBI-374900

    Stoichiometry: 0.0

    F
    Participant: DNA replication licensing factor MCM6

    Participant: DNA replication licensing factor MCM6

    Accession: EBI-21839637

    Name: EBI-374900

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication licensing factor MCM6

    Participant: DNA replication licensing factor MCM6

    Accession: EBI-21839637

    Name: EBI-374900

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.88101286391616396
    Non-specific binding CompPASS-Plus score: 0.118987136083536
    False-positive CompPASS-Plus score: 2.99804211137184E-13

    9
    EBI-718662
     logo
    MMS22L
    C6orf167
    Methyl methanesulfonate-sensitivity protein 22-like
    Protein MMS22-like
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein MMS22-like

    Participant: Protein MMS22-like

    Accession: EBI-21839643

    Name: EBI-718662

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Protein MMS22-like

    Participant: Protein MMS22-like

    Accession: EBI-21839643

    Name: EBI-718662

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein MMS22-like

    Participant: Protein MMS22-like

    Accession: EBI-21839643

    Name: EBI-718662

    Stoichiometry: 0.0

    F
    Participant: Protein MMS22-like

    Participant: Protein MMS22-like

    Accession: EBI-21839643

    Name: EBI-718662

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein MMS22-like

    Participant: Protein MMS22-like

    Accession: EBI-21839643

    Name: EBI-718662

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999581718060304
    Non-specific binding CompPASS-Plus score: 4.1824281169000004E-6
    False-positive CompPASS-Plus score: 3.9127978205348602E-10

    10
    EBI-2515547
     logo
    SUPT6H
    KIAA0162
    SPT6H

    [+2]
    Transcription elongation factor SPT6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Transcription elongation factor SPT6

    Participant: Transcription elongation factor SPT6

    Accession: EBI-21839649

    Name: EBI-2515547

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Transcription elongation factor SPT6

    Participant: Transcription elongation factor SPT6

    Accession: EBI-21839649

    Name: EBI-2515547

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Transcription elongation factor SPT6

    Participant: Transcription elongation factor SPT6

    Accession: EBI-21839649

    Name: EBI-2515547

    Stoichiometry: 0.0

    F
    Participant: Transcription elongation factor SPT6

    Participant: Transcription elongation factor SPT6

    Accession: EBI-21839649

    Name: EBI-2515547

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Transcription elongation factor SPT6

    Participant: Transcription elongation factor SPT6

    Accession: EBI-21839649

    Name: EBI-2515547

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.89494045054271998
    Non-specific binding CompPASS-Plus score: 0.105059549147034
    False-positive CompPASS-Plus score: 3.1024623739952199E-10

    11
    EBI-1642157
     logo
    H2AC21
    H2A-clustered histone 21
    HIST2H2AB
    Histone H2A type 2-B
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Histone H2A type 2-B

    Participant: Histone H2A type 2-B

    Accession: EBI-21839655

    Name: EBI-1642157

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Histone H2A type 2-B

    Participant: Histone H2A type 2-B

    Accession: EBI-21839655

    Name: EBI-1642157

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Histone H2A type 2-B

    Participant: Histone H2A type 2-B

    Accession: EBI-21839655

    Name: EBI-1642157

    Stoichiometry: 0.0

    F
    Participant: Histone H2A type 2-B

    Participant: Histone H2A type 2-B

    Accession: EBI-21839655

    Name: EBI-1642157

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Histone H2A type 2-B

    Participant: Histone H2A type 2-B

    Accession: EBI-21839655

    Name: EBI-1642157

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.93510728828298295
    Non-specific binding CompPASS-Plus score: 6.4892531368892101E-2
    False-positive CompPASS-Plus score: 1.8034812461554E-7

    12
    EBI-1052467
     logo
    IKBR
    Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2
    Inhibitor of kappa B-related protein

    [+3]
    Tonsoku-like protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Tonsoku-like protein

    Participant: Tonsoku-like protein

    Accession: EBI-21839661

    Name: EBI-1052467

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Tonsoku-like protein

    Participant: Tonsoku-like protein

    Accession: EBI-21839661

    Name: EBI-1052467

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Tonsoku-like protein

    Participant: Tonsoku-like protein

    Accession: EBI-21839661

    Name: EBI-1052467

    Stoichiometry: 0.0

    F
    Participant: Tonsoku-like protein

    Participant: Tonsoku-like protein

    Accession: EBI-21839661

    Name: EBI-1052467

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Tonsoku-like protein

    Participant: Tonsoku-like protein

    Accession: EBI-21839661

    Name: EBI-1052467

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999905221218599
    Non-specific binding CompPASS-Plus score: 9.4776640562048197E-7
    False-positive CompPASS-Plus score: 2.1408448542169499E-11

    13
    EBI-747500
     logo
    SLD5
    GINS complex subunit 4
    GINS4
    DNA replication complex GINS protein SLD5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA replication complex GINS protein SLD5

    Participant: DNA replication complex GINS protein SLD5

    Accession: EBI-21839667

    Name: EBI-747500

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: DNA replication complex GINS protein SLD5

    Participant: DNA replication complex GINS protein SLD5

    Accession: EBI-21839667

    Name: EBI-747500

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DNA replication complex GINS protein SLD5

    Participant: DNA replication complex GINS protein SLD5

    Accession: EBI-21839667

    Name: EBI-747500

    Stoichiometry: 0.0

    F
    Participant: DNA replication complex GINS protein SLD5

    Participant: DNA replication complex GINS protein SLD5

    Accession: EBI-21839667

    Name: EBI-747500

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA replication complex GINS protein SLD5

    Participant: DNA replication complex GINS protein SLD5

    Accession: EBI-21839667

    Name: EBI-747500

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.87815452577167596
    Non-specific binding CompPASS-Plus score: 0.121670728272427
    False-positive CompPASS-Plus score: 1.7474595589778001E-4

    14
    EBI-1907289
     logo
    EPB41L5
    KIAA1548
    Erythrocyte membrane protein band 4.1-like 5
    Band 4.1-like protein 5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Band 4.1-like protein 5

    Participant: Band 4.1-like protein 5

    Accession: EBI-21839673

    Name: EBI-1907289

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Band 4.1-like protein 5

    Participant: Band 4.1-like protein 5

    Accession: EBI-21839673

    Name: EBI-1907289

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Band 4.1-like protein 5

    Participant: Band 4.1-like protein 5

    Accession: EBI-21839673

    Name: EBI-1907289

    Stoichiometry: 0.0

    F
    Participant: Band 4.1-like protein 5

    Participant: Band 4.1-like protein 5

    Accession: EBI-21839673

    Name: EBI-1907289

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Band 4.1-like protein 5

    Participant: Band 4.1-like protein 5

    Accession: EBI-21839673

    Name: EBI-1907289

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.93739848857781405
    Non-specific binding CompPASS-Plus score: 6.2601511422079106E-2
    False-positive CompPASS-Plus score: 1.06438913529092E-13

    15
    EBI-10966243
     logo
    TIMELESS
    TIM
    TIM1

    [+1]
    Protein timeless homolog
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein timeless homolog

    Participant: Protein timeless homolog

    Accession: EBI-21839679

    Name: EBI-10966243

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Protein timeless homolog

    Participant: Protein timeless homolog

    Accession: EBI-21839679

    Name: EBI-10966243

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein timeless homolog

    Participant: Protein timeless homolog

    Accession: EBI-21839679

    Name: EBI-10966243

    Stoichiometry: 0.0

    F
    Participant: Protein timeless homolog

    Participant: Protein timeless homolog

    Accession: EBI-21839679

    Name: EBI-10966243

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein timeless homolog

    Participant: Protein timeless homolog

    Accession: EBI-21839679

    Name: EBI-10966243

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99755062865423305
    Non-specific binding CompPASS-Plus score: 2.4493712928977101E-3
    False-positive CompPASS-Plus score: 5.2869250901088303E-11

    16
    EBI-21539630
     logo
    TRAPPC8
    KIAA1012
    Isoform 2 of Trafficking protein particle complex subunit 8
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Accession: EBI-21839685

    Name: EBI-21539630

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Accession: EBI-21839685

    Name: EBI-21539630

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Accession: EBI-21839685

    Name: EBI-21539630

    Stoichiometry: 0.0

    F
    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Accession: EBI-21839685

    Name: EBI-21539630

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Participant: Isoform 2 of Trafficking protein particle complex subunit 8

    Accession: EBI-21839685

    Name: EBI-21539630

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98609115110393197
    Non-specific binding CompPASS-Plus score: 1.3908848895972801E-2
    False-positive CompPASS-Plus score: 9.5409934270227402E-14

    17
    EBI-1046849
     logo
    Facilitates chromatin transcription complex subunit SPT16
    FACT 140 kDa subunit
    FACTp140

    [+4]
    FACT complex subunit SPT16
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: FACT complex subunit SPT16

    Participant: FACT complex subunit SPT16

    Accession: EBI-21839691

    Name: EBI-1046849

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: FACT complex subunit SPT16

    Participant: FACT complex subunit SPT16

    Accession: EBI-21839691

    Name: EBI-1046849

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: FACT complex subunit SPT16

    Participant: FACT complex subunit SPT16

    Accession: EBI-21839691

    Name: EBI-1046849

    Stoichiometry: 0.0

    F
    Participant: FACT complex subunit SPT16

    Participant: FACT complex subunit SPT16

    Accession: EBI-21839691

    Name: EBI-1046849

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: FACT complex subunit SPT16

    Participant: FACT complex subunit SPT16

    Accession: EBI-21839691

    Name: EBI-1046849

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99998951799056701
    Non-specific binding CompPASS-Plus score: 1.04819559956401E-5
    False-positive CompPASS-Plus score: 5.3437701855293699E-11


    Graphical Representation of Experimental Features