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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 28514442

Journal: Nature

Year of Publication: 2017

Title: Architecture of the human interactome defines protein communities and disease networks.

Author List: Huttlin EL., Bruckner RJ., Paulo JA., Cannon JR., Ting L., Baltier K., Colby G., Gebreab F., Gygi MP., Parzen H., Szpyt J., Tam S., Zarraga G., Pontano-Vaites L., Swarup S., White AE., Schweppe DK., Rad R., Erickson BK., Obar RA., Guruharsha KG., Li K., Artavanis-Tsakonas S., Gygi SP., Harper JW.

Cross References:

Experiment (5110 interactions)

Accession: EBI-21498811

Name: huttlin-2017-3

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
Experimental roles have been inferred upon counting participant occurrences and might not reflect the actual constructs used in the original experiments. Interactions depicted in this experiment may be an aggregate from different co-immunoprecipitations, using bait constructs that may or may not represent the full length sequence of the referenced protein.
edward_huttlin@hms.harvard.edu,steven.gygi@hms.harvard.edu,wade_harper@hms.harvard.edu
imex curation

Interaction

Accession: EBI-21644875

Name: prkacb-akap1-2

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Supplementary table 1

Participants (19)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
1
EBI-5258763
 logo
Beta2
PRKACB
cAMP-dependent protein kinase catalytic subunit beta
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: cAMP-dependent protein kinase catalytic subunit beta

Participant: cAMP-dependent protein kinase catalytic subunit beta

Accession: EBI-21644877

Name: EBI-5258763

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: cAMP-dependent protein kinase catalytic subunit beta

Participant: cAMP-dependent protein kinase catalytic subunit beta

Accession: EBI-21644877

Name: EBI-5258763

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: cAMP-dependent protein kinase catalytic subunit beta

Participant: cAMP-dependent protein kinase catalytic subunit beta

Accession: EBI-21644877

Name: EBI-5258763

Stoichiometry: 0.0

F
Participant: cAMP-dependent protein kinase catalytic subunit beta

Participant: cAMP-dependent protein kinase catalytic subunit beta

Accession: EBI-21644877

Name: EBI-5258763

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
C-terminal HA-flag tag
  • c-c
  • A
    Feature: EBI-21644879

    Feature: C-terminal HA-flag tag

    Accession: EBI-21644879

    Name: C-terminal HA-flag tag


    C
    Participant: cAMP-dependent protein kinase catalytic subunit beta

    Participant: cAMP-dependent protein kinase catalytic subunit beta

    Accession: EBI-21644877

    Name: EBI-5258763

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-1105124
     logo
    PDE4DIP
    CMYA2
    KIAA0454

    [+4]
    Myomegalin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Myomegalin

    Participant: Myomegalin

    Accession: EBI-21644882

    Name: EBI-1105124

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Myomegalin

    Participant: Myomegalin

    Accession: EBI-21644882

    Name: EBI-1105124

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Myomegalin

    Participant: Myomegalin

    Accession: EBI-21644882

    Name: EBI-1105124

    Stoichiometry: 0.0

    F
    Participant: Myomegalin

    Participant: Myomegalin

    Accession: EBI-21644882

    Name: EBI-1105124

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Myomegalin

    Participant: Myomegalin

    Accession: EBI-21644882

    Name: EBI-1105124

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999976324321305
    Non-specific binding CompPASS-Plus score: 2.36651667230308E-7
    False-positive CompPASS-Plus score: 1.05120261745804E-10

    3
    EBI-476431
     logo
    Tissue-specific extinguisher 1
    PRKAR1A
    PKR1

    [+2]
    cAMP-dependent protein kinase type I-alpha regulatory subunit
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Accession: EBI-21644888

    Name: EBI-476431

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Accession: EBI-21644888

    Name: EBI-476431

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Accession: EBI-21644888

    Name: EBI-476431

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Accession: EBI-21644888

    Name: EBI-476431

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type I-alpha regulatory subunit

    Accession: EBI-21644888

    Name: EBI-476431

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999999343616996
    Non-specific binding CompPASS-Plus score: 6.5638277621898999E-9
    False-positive CompPASS-Plus score: 3.0811980553346E-22

    4
    EBI-2556122
     logo
    PKR2
    PRKAR2
    PRKAR2A
    cAMP-dependent protein kinase type II-alpha regulatory subunit
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Accession: EBI-21644894

    Name: EBI-2556122

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Accession: EBI-21644894

    Name: EBI-2556122

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Accession: EBI-21644894

    Name: EBI-2556122

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Accession: EBI-21644894

    Name: EBI-2556122

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Participant: cAMP-dependent protein kinase type II-alpha regulatory subunit

    Accession: EBI-21644894

    Name: EBI-2556122

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97849901574121101
    Non-specific binding CompPASS-Plus score: 2.1500984258789001E-2
    False-positive CompPASS-Plus score: 4.22944008519097E-16

    5
    EBI-6137797
     logo
    C-alpha-2
    C-alpha-S
    C(s)

    [+2]
    cAMP-dependent protein kinase catalytic subunit alpha
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Accession: EBI-21644900

    Name: EBI-6137797

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Accession: EBI-21644900

    Name: EBI-6137797

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Accession: EBI-21644900

    Name: EBI-6137797

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Accession: EBI-21644900

    Name: EBI-6137797

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Participant: cAMP-dependent protein kinase catalytic subunit alpha

    Accession: EBI-21644900

    Name: EBI-6137797

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.996082592567198
    Non-specific binding CompPASS-Plus score: 3.9174074320604104E-3
    False-positive CompPASS-Plus score: 7.4133831325195896E-13

    6
    EBI-3907086
     logo
    PRKACG
    cAMP-dependent protein kinase catalytic subunit gamma
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Accession: EBI-21644906

    Name: EBI-3907086

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Accession: EBI-21644906

    Name: EBI-3907086

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Accession: EBI-21644906

    Name: EBI-3907086

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Accession: EBI-21644906

    Name: EBI-3907086

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Participant: cAMP-dependent protein kinase catalytic subunit gamma

    Accession: EBI-21644906

    Name: EBI-3907086

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99995865948133
    Non-specific binding CompPASS-Plus score: 4.1340518667197997E-5
    False-positive CompPASS-Plus score: 2.8603800656459999E-15

    7
    EBI-703640
     logo
    A-kinase anchor protein 79 kDa
    cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
    H21

    [+2]
    A-kinase anchor protein 5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 5

    Participant: A-kinase anchor protein 5

    Accession: EBI-21644912

    Name: EBI-703640

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 5

    Participant: A-kinase anchor protein 5

    Accession: EBI-21644912

    Name: EBI-703640

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 5

    Participant: A-kinase anchor protein 5

    Accession: EBI-21644912

    Name: EBI-703640

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 5

    Participant: A-kinase anchor protein 5

    Accession: EBI-21644912

    Name: EBI-703640

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 5

    Participant: A-kinase anchor protein 5

    Accession: EBI-21644912

    Name: EBI-703640

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999746862718297
    Non-specific binding CompPASS-Plus score: 7.0544237331204697E-7
    False-positive CompPASS-Plus score: 1.82593044373904E-6

    8
    EBI-2805516
     logo
    PRKAR1B
    cAMP-dependent protein kinase type I-beta regulatory subunit
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Accession: EBI-21644918

    Name: EBI-2805516

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Accession: EBI-21644918

    Name: EBI-2805516

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Accession: EBI-21644918

    Name: EBI-2805516

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Accession: EBI-21644918

    Name: EBI-2805516

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type I-beta regulatory subunit

    Accession: EBI-21644918

    Name: EBI-2805516

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99997587196632498
    Non-specific binding CompPASS-Plus score: 2.4121255283308098E-5
    False-positive CompPASS-Plus score: 6.7783920350434302E-9

    9
    EBI-2930670
     logo
    PRKAR2B
    cAMP-dependent protein kinase type II-beta regulatory subunit
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Accession: EBI-21644924

    Name: EBI-2930670

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Accession: EBI-21644924

    Name: EBI-2930670

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Accession: EBI-21644924

    Name: EBI-2930670

    Stoichiometry: 0.0

    F
    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Accession: EBI-21644924

    Name: EBI-2930670

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Participant: cAMP-dependent protein kinase type II-beta regulatory subunit

    Accession: EBI-21644924

    Name: EBI-2930670

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999999999939004
    Non-specific binding CompPASS-Plus score: 6.1321103924424004E-13
    False-positive CompPASS-Plus score: 4.7003918017444001E-24

    10
    EBI-21644869
     logo
    ETFB
    FP585
    Isoform 2 of Electron transfer flavoprotein subunit beta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Accession: EBI-21644930

    Name: EBI-21644869

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Accession: EBI-21644930

    Name: EBI-21644869

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Accession: EBI-21644930

    Name: EBI-21644869

    Stoichiometry: 0.0

    F
    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Accession: EBI-21644930

    Name: EBI-21644869

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Participant: Isoform 2 of Electron transfer flavoprotein subunit beta

    Accession: EBI-21644930

    Name: EBI-21644869

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.95547458401378005
    Non-specific binding CompPASS-Plus score: 4.4525415986214997E-2
    False-positive CompPASS-Plus score: 6.5761955881834993E-27

    11
    EBI-306914
     logo
    FKBP5
    AIG6
    FKBP51

    [+8]
    Peptidyl-prolyl cis-trans isomerase FKBP5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Accession: EBI-21644936

    Name: EBI-306914

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Accession: EBI-21644936

    Name: EBI-306914

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Accession: EBI-21644936

    Name: EBI-306914

    Stoichiometry: 0.0

    F
    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Accession: EBI-21644936

    Name: EBI-306914

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Participant: Peptidyl-prolyl cis-trans isomerase FKBP5

    Accession: EBI-21644936

    Name: EBI-306914

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99471347924111297
    Non-specific binding CompPASS-Plus score: 5.2865207072845298E-3
    False-positive CompPASS-Plus score: 5.16030158039101E-11

    12
    EBI-1053621
     logo
    DYRK1A
    DYRK
    MNB

    [+4]
    Dual specificity tyrosine-phosphorylation-regulated kinase 1A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Accession: EBI-21644942

    Name: EBI-1053621

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Accession: EBI-21644942

    Name: EBI-1053621

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Accession: EBI-21644942

    Name: EBI-1053621

    Stoichiometry: 0.0

    F
    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Accession: EBI-21644942

    Name: EBI-1053621

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Participant: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

    Accession: EBI-21644942

    Name: EBI-1053621

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99428328298439295
    Non-specific binding CompPASS-Plus score: 5.7167170155703103E-3
    False-positive CompPASS-Plus score: 3.63862903686616E-14

    13
    EBI-6916503
     logo
    HSP90AB4P
    Putative heat shock protein HSP 90-beta 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Putative heat shock protein HSP 90-beta 4

    Participant: Putative heat shock protein HSP 90-beta 4

    Accession: EBI-21644948

    Name: EBI-6916503

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Putative heat shock protein HSP 90-beta 4

    Participant: Putative heat shock protein HSP 90-beta 4

    Accession: EBI-21644948

    Name: EBI-6916503

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Putative heat shock protein HSP 90-beta 4

    Participant: Putative heat shock protein HSP 90-beta 4

    Accession: EBI-21644948

    Name: EBI-6916503

    Stoichiometry: 0.0

    F
    Participant: Putative heat shock protein HSP 90-beta 4

    Participant: Putative heat shock protein HSP 90-beta 4

    Accession: EBI-21644948

    Name: EBI-6916503

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Putative heat shock protein HSP 90-beta 4

    Participant: Putative heat shock protein HSP 90-beta 4

    Accession: EBI-21644948

    Name: EBI-6916503

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99981764282255503
    Non-specific binding CompPASS-Plus score: 1.8235713273952601E-4
    False-positive CompPASS-Plus score: 4.4705477309657498E-11

    14
    EBI-6255622
     logo
    GPR161
    G-protein coupled receptor RE2
    G-protein coupled receptor 161
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: G-protein coupled receptor 161

    Participant: G-protein coupled receptor 161

    Accession: EBI-21644954

    Name: EBI-6255622

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: G-protein coupled receptor 161

    Participant: G-protein coupled receptor 161

    Accession: EBI-21644954

    Name: EBI-6255622

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: G-protein coupled receptor 161

    Participant: G-protein coupled receptor 161

    Accession: EBI-21644954

    Name: EBI-6255622

    Stoichiometry: 0.0

    F
    Participant: G-protein coupled receptor 161

    Participant: G-protein coupled receptor 161

    Accession: EBI-21644954

    Name: EBI-6255622

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: G-protein coupled receptor 161

    Participant: G-protein coupled receptor 161

    Accession: EBI-21644954

    Name: EBI-6255622

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999924152813002
    Non-specific binding CompPASS-Plus score: 7.5847181547254005E-7
    False-positive CompPASS-Plus score: 5.3239881707497998E-14

    15
    EBI-2120060
     logo
    AKAP1
    AKAP149
    PRKA1

    [+5]
    A-kinase anchor protein 1, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 1, mitochondrial

    Participant: A-kinase anchor protein 1, mitochondrial

    Accession: EBI-21644960

    Name: EBI-2120060

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 1, mitochondrial

    Participant: A-kinase anchor protein 1, mitochondrial

    Accession: EBI-21644960

    Name: EBI-2120060

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 1, mitochondrial

    Participant: A-kinase anchor protein 1, mitochondrial

    Accession: EBI-21644960

    Name: EBI-2120060

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 1, mitochondrial

    Participant: A-kinase anchor protein 1, mitochondrial

    Accession: EBI-21644960

    Name: EBI-2120060

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 1, mitochondrial

    Participant: A-kinase anchor protein 1, mitochondrial

    Accession: EBI-21644960

    Name: EBI-2120060

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99994261574379395
    Non-specific binding CompPASS-Plus score: 5.7384236980357299E-5
    False-positive CompPASS-Plus score: 1.92251951262645E-11

    16
    EBI-21545131
     logo
    CDK5RAP2
    CEP215
    KIAA1633

    [+2]
    CDK5 regulatory subunit-associated protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: CDK5 regulatory subunit-associated protein 2

    Participant: CDK5 regulatory subunit-associated protein 2

    Accession: EBI-21644966

    Name: EBI-21545131

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: CDK5 regulatory subunit-associated protein 2

    Participant: CDK5 regulatory subunit-associated protein 2

    Accession: EBI-21644966

    Name: EBI-21545131

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: CDK5 regulatory subunit-associated protein 2

    Participant: CDK5 regulatory subunit-associated protein 2

    Accession: EBI-21644966

    Name: EBI-21545131

    Stoichiometry: 0.0

    F
    Participant: CDK5 regulatory subunit-associated protein 2

    Participant: CDK5 regulatory subunit-associated protein 2

    Accession: EBI-21644966

    Name: EBI-21545131

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: CDK5 regulatory subunit-associated protein 2

    Participant: CDK5 regulatory subunit-associated protein 2

    Accession: EBI-21644966

    Name: EBI-21545131

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.998174880205555
    Non-specific binding CompPASS-Plus score: 1.8251197913740501E-3
    False-positive CompPASS-Plus score: 3.0708006197224901E-12

    17
    EBI-9641546
     logo
    AKAP9
    A-kinase anchor protein 350 kDa
    A-kinase anchor protein 450 kDa

    [+8]
    A-kinase anchor protein 9
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 9

    Participant: A-kinase anchor protein 9

    Accession: EBI-21644972

    Name: EBI-9641546

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 9

    Participant: A-kinase anchor protein 9

    Accession: EBI-21644972

    Name: EBI-9641546

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 9

    Participant: A-kinase anchor protein 9

    Accession: EBI-21644972

    Name: EBI-9641546

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 9

    Participant: A-kinase anchor protein 9

    Accession: EBI-21644972

    Name: EBI-9641546

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 9

    Participant: A-kinase anchor protein 9

    Accession: EBI-21644972

    Name: EBI-9641546

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999883474915596
    Non-specific binding CompPASS-Plus score: 1.1648334126483799E-6
    False-positive CompPASS-Plus score: 4.1743173843925398E-10

    18
    EBI-2512902
     logo
    AKAP7
    AKAP18
    Protein kinase A-anchoring protein 7 isoform gamma

    [+1]
    A-kinase anchor protein 7 isoform gamma
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 7 isoform gamma

    Participant: A-kinase anchor protein 7 isoform gamma

    Accession: EBI-21644978

    Name: EBI-2512902

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 7 isoform gamma

    Participant: A-kinase anchor protein 7 isoform gamma

    Accession: EBI-21644978

    Name: EBI-2512902

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 7 isoform gamma

    Participant: A-kinase anchor protein 7 isoform gamma

    Accession: EBI-21644978

    Name: EBI-2512902

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 7 isoform gamma

    Participant: A-kinase anchor protein 7 isoform gamma

    Accession: EBI-21644978

    Name: EBI-2512902

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 7 isoform gamma

    Participant: A-kinase anchor protein 7 isoform gamma

    Accession: EBI-21644978

    Name: EBI-2512902

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999895981831
    Non-specific binding CompPASS-Plus score: 1.0184301363037099E-6
    False-positive CompPASS-Plus score: 2.1751553401545202E-8

    19
    EBI-1049491
     logo
    Protein kinase A-anchoring protein 11
    A-kinase anchor protein 220 kDa
    AKAP11

    [+2]
    A-kinase anchor protein 11
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: A-kinase anchor protein 11

    Participant: A-kinase anchor protein 11

    Accession: EBI-21644984

    Name: EBI-1049491

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: A-kinase anchor protein 11

    Participant: A-kinase anchor protein 11

    Accession: EBI-21644984

    Name: EBI-1049491

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: A-kinase anchor protein 11

    Participant: A-kinase anchor protein 11

    Accession: EBI-21644984

    Name: EBI-1049491

    Stoichiometry: 0.0

    F
    Participant: A-kinase anchor protein 11

    Participant: A-kinase anchor protein 11

    Accession: EBI-21644984

    Name: EBI-1049491

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: A-kinase anchor protein 11

    Participant: A-kinase anchor protein 11

    Accession: EBI-21644984

    Name: EBI-1049491

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999803504088802
    Non-specific binding CompPASS-Plus score: 1.9649588248853501E-6
    False-positive CompPASS-Plus score: 2.87118666441392E-13


    Graphical Representation of Experimental Features