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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 28514442

Journal: Nature

Year of Publication: 2017

Title: Architecture of the human interactome defines protein communities and disease networks.

Author List: Huttlin EL., Bruckner RJ., Paulo JA., Cannon JR., Ting L., Baltier K., Colby G., Gebreab F., Gygi MP., Parzen H., Szpyt J., Tam S., Zarraga G., Pontano-Vaites L., Swarup S., White AE., Schweppe DK., Rad R., Erickson BK., Obar RA., Guruharsha KG., Li K., Artavanis-Tsakonas S., Gygi SP., Harper JW.

Cross References:

Experiment (5110 interactions)

Accession: EBI-21498811

Name: huttlin-2017-3

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
Experimental roles have been inferred upon counting participant occurrences and might not reflect the actual constructs used in the original experiments. Interactions depicted in this experiment may be an aggregate from different co-immunoprecipitations, using bait constructs that may or may not represent the full length sequence of the referenced protein.
edward_huttlin@hms.harvard.edu,steven.gygi@hms.harvard.edu,wade_harper@hms.harvard.edu
imex curation

Interaction

Accession: EBI-21621073

Name: gmnn-bag4-1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Supplementary table 1

Participants (30)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12pp
1
EBI-371669
 logo
GMNN
Geminin
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Geminin

Participant: Geminin

Accession: EBI-21621075

Name: EBI-371669

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: Geminin

Participant: Geminin

Accession: EBI-21621075

Name: EBI-371669

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Geminin

Participant: Geminin

Accession: EBI-21621075

Name: EBI-371669

Stoichiometry: 0.0

F
Participant: Geminin

Participant: Geminin

Accession: EBI-21621075

Name: EBI-371669

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
C-terminal HA-flag tag
  • c-c
  • A
    Feature: EBI-21621077

    Feature: C-terminal HA-flag tag

    Accession: EBI-21621077

    Name: C-terminal HA-flag tag


    C
    Participant: Geminin

    Participant: Geminin

    Accession: EBI-21621075

    Name: EBI-371669

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-3954372
     logo
    MCIDAS
    IDAS
    MCI

    [+3]
    Multicilin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Multicilin

    Participant: Multicilin

    Accession: EBI-21621080

    Name: EBI-3954372

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Multicilin

    Participant: Multicilin

    Accession: EBI-21621080

    Name: EBI-3954372

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Multicilin

    Participant: Multicilin

    Accession: EBI-21621080

    Name: EBI-3954372

    Stoichiometry: 0.0

    F
    Participant: Multicilin

    Participant: Multicilin

    Accession: EBI-21621080

    Name: EBI-3954372

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Multicilin

    Participant: Multicilin

    Accession: EBI-21621080

    Name: EBI-3954372

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98289397427733105
    Non-specific binding CompPASS-Plus score: 3.91503496781306E-7
    False-positive CompPASS-Plus score: 1.71056342191717E-2

    3
    EBI-2339778
     logo
    CEP192
    KIAA1569
    PP8407
    Centrosomal protein of 192 kDa
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Centrosomal protein of 192 kDa

    Participant: Centrosomal protein of 192 kDa

    Accession: EBI-21621086

    Name: EBI-2339778

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Centrosomal protein of 192 kDa

    Participant: Centrosomal protein of 192 kDa

    Accession: EBI-21621086

    Name: EBI-2339778

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Centrosomal protein of 192 kDa

    Participant: Centrosomal protein of 192 kDa

    Accession: EBI-21621086

    Name: EBI-2339778

    Stoichiometry: 0.0

    F
    Participant: Centrosomal protein of 192 kDa

    Participant: Centrosomal protein of 192 kDa

    Accession: EBI-21621086

    Name: EBI-2339778

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Centrosomal protein of 192 kDa

    Participant: Centrosomal protein of 192 kDa

    Accession: EBI-21621086

    Name: EBI-2339778

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99112231532545303
    Non-specific binding CompPASS-Plus score: 2.1969756576485401E-3
    False-positive CompPASS-Plus score: 6.6807090168982302E-3

    4
    EBI-2340316
     logo
    MID1
    FXY
    RNF59

    [+8]
    E3 ubiquitin-protein ligase Midline-1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase Midline-1

    Participant: E3 ubiquitin-protein ligase Midline-1

    Accession: EBI-21621092

    Name: EBI-2340316

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: E3 ubiquitin-protein ligase Midline-1

    Participant: E3 ubiquitin-protein ligase Midline-1

    Accession: EBI-21621092

    Name: EBI-2340316

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase Midline-1

    Participant: E3 ubiquitin-protein ligase Midline-1

    Accession: EBI-21621092

    Name: EBI-2340316

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase Midline-1

    Participant: E3 ubiquitin-protein ligase Midline-1

    Accession: EBI-21621092

    Name: EBI-2340316

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase Midline-1

    Participant: E3 ubiquitin-protein ligase Midline-1

    Accession: EBI-21621092

    Name: EBI-2340316

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99955407042280797
    Non-specific binding CompPASS-Plus score: 4.45929294340223E-4
    False-positive CompPASS-Plus score: 2.82851803362594E-10

    5
    EBI-715672
     logo
    ZZEF1
    KIAA0399
    Zinc finger ZZ-type and EF-hand domain-containing protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Accession: EBI-21621098

    Name: EBI-715672

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Accession: EBI-21621098

    Name: EBI-715672

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Accession: EBI-21621098

    Name: EBI-715672

    Stoichiometry: 0.0

    F
    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Accession: EBI-21621098

    Name: EBI-715672

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Participant: Zinc finger ZZ-type and EF-hand domain-containing protein 1

    Accession: EBI-21621098

    Name: EBI-715672

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.75637238496082004
    Non-specific binding CompPASS-Plus score: 0.24362761460753299
    False-positive CompPASS-Plus score: 4.3164702897351602E-10

    6
    EBI-7874815
     logo
    HMMR
    B
    IHABP

    [+3]
    Hyaluronan mediated motility receptor
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Hyaluronan mediated motility receptor

    Participant: Hyaluronan mediated motility receptor

    Accession: EBI-21621104

    Name: EBI-7874815

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Hyaluronan mediated motility receptor

    Participant: Hyaluronan mediated motility receptor

    Accession: EBI-21621104

    Name: EBI-7874815

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Hyaluronan mediated motility receptor

    Participant: Hyaluronan mediated motility receptor

    Accession: EBI-21621104

    Name: EBI-7874815

    Stoichiometry: 0.0

    F
    Participant: Hyaluronan mediated motility receptor

    Participant: Hyaluronan mediated motility receptor

    Accession: EBI-21621104

    Name: EBI-7874815

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Hyaluronan mediated motility receptor

    Participant: Hyaluronan mediated motility receptor

    Accession: EBI-21621104

    Name: EBI-7874815

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99964662401120397
    Non-specific binding CompPASS-Plus score: 3.5337177097084099E-4
    False-positive CompPASS-Plus score: 4.2178247559008398E-9

    7
    EBI-2949658
     logo
    BAG4
    SODD
    Bcl-2-associated athanogene 4

    [+1]
    BAG family molecular chaperone regulator 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: BAG family molecular chaperone regulator 4

    Participant: BAG family molecular chaperone regulator 4

    Accession: EBI-21621110

    Name: EBI-2949658

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: BAG family molecular chaperone regulator 4

    Participant: BAG family molecular chaperone regulator 4

    Accession: EBI-21621110

    Name: EBI-2949658

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: BAG family molecular chaperone regulator 4

    Participant: BAG family molecular chaperone regulator 4

    Accession: EBI-21621110

    Name: EBI-2949658

    Stoichiometry: 0.0

    F
    Participant: BAG family molecular chaperone regulator 4

    Participant: BAG family molecular chaperone regulator 4

    Accession: EBI-21621110

    Name: EBI-2949658

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: BAG family molecular chaperone regulator 4

    Participant: BAG family molecular chaperone regulator 4

    Accession: EBI-21621110

    Name: EBI-2949658

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97856291603262002
    Non-specific binding CompPASS-Plus score: 2.1437083967381001E-2
    False-positive CompPASS-Plus score: 1.1447843577317E-18

    8
    EBI-444308
     logo
    p34 protein kinase
    Cell division protein kinase 1
    CDK1

    [+5]
    Cyclin-dependent kinase 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cyclin-dependent kinase 1

    Participant: Cyclin-dependent kinase 1

    Accession: EBI-21621116

    Name: EBI-444308

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Cyclin-dependent kinase 1

    Participant: Cyclin-dependent kinase 1

    Accession: EBI-21621116

    Name: EBI-444308

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cyclin-dependent kinase 1

    Participant: Cyclin-dependent kinase 1

    Accession: EBI-21621116

    Name: EBI-444308

    Stoichiometry: 0.0

    F
    Participant: Cyclin-dependent kinase 1

    Participant: Cyclin-dependent kinase 1

    Accession: EBI-21621116

    Name: EBI-444308

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cyclin-dependent kinase 1

    Participant: Cyclin-dependent kinase 1

    Accession: EBI-21621116

    Name: EBI-444308

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97177157529994995
    Non-specific binding CompPASS-Plus score: 2.8228424700053999E-2
    False-positive CompPASS-Plus score: 3.0135746660607001E-16

    9
    EBI-351896
     logo
    HSPA8
    HSC70
    HSP73

    [+3]
    Heat shock cognate 71 kDa protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-21621122

    Name: EBI-351896

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-21621122

    Name: EBI-351896

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-21621122

    Name: EBI-351896

    Stoichiometry: 0.0

    F
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-21621122

    Name: EBI-351896

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-21621122

    Name: EBI-351896

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99878800531534995
    Non-specific binding CompPASS-Plus score: 1.2119946846453E-3
    False-positive CompPASS-Plus score: 2.2543399275556999E-23

    10
    EBI-457097
     logo
    Cyclin A
    CCNA2
    CCN1

    [+1]
    Cyclin-A2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cyclin-A2

    Participant: Cyclin-A2

    Accession: EBI-21621128

    Name: EBI-457097

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Cyclin-A2

    Participant: Cyclin-A2

    Accession: EBI-21621128

    Name: EBI-457097

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cyclin-A2

    Participant: Cyclin-A2

    Accession: EBI-21621128

    Name: EBI-457097

    Stoichiometry: 0.0

    F
    Participant: Cyclin-A2

    Participant: Cyclin-A2

    Accession: EBI-21621128

    Name: EBI-457097

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cyclin-A2

    Participant: Cyclin-A2

    Accession: EBI-21621128

    Name: EBI-457097

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999999880154999
    Non-specific binding CompPASS-Plus score: 1.1984526235267001E-9
    False-positive CompPASS-Plus score: 4.9166656186327998E-20

    11
    EBI-375096
     logo
    CDK2
    p33 protein kinase
    Cell division protein kinase 2

    [+1]
    Cyclin-dependent kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cyclin-dependent kinase 2

    Participant: Cyclin-dependent kinase 2

    Accession: EBI-21621134

    Name: EBI-375096

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Cyclin-dependent kinase 2

    Participant: Cyclin-dependent kinase 2

    Accession: EBI-21621134

    Name: EBI-375096

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cyclin-dependent kinase 2

    Participant: Cyclin-dependent kinase 2

    Accession: EBI-21621134

    Name: EBI-375096

    Stoichiometry: 0.0

    F
    Participant: Cyclin-dependent kinase 2

    Participant: Cyclin-dependent kinase 2

    Accession: EBI-21621134

    Name: EBI-375096

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cyclin-dependent kinase 2

    Participant: Cyclin-dependent kinase 2

    Accession: EBI-21621134

    Name: EBI-375096

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999626538131003
    Non-specific binding CompPASS-Plus score: 3.7346186859030999E-6
    False-positive CompPASS-Plus score: 2.7564219883904E-21

    12
    EBI-1383454
     logo
    TYK2
    Non-receptor tyrosine-protein kinase TYK2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Non-receptor tyrosine-protein kinase TYK2

    Participant: Non-receptor tyrosine-protein kinase TYK2

    Accession: EBI-21621140

    Name: EBI-1383454

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Non-receptor tyrosine-protein kinase TYK2

    Participant: Non-receptor tyrosine-protein kinase TYK2

    Accession: EBI-21621140

    Name: EBI-1383454

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Non-receptor tyrosine-protein kinase TYK2

    Participant: Non-receptor tyrosine-protein kinase TYK2

    Accession: EBI-21621140

    Name: EBI-1383454

    Stoichiometry: 0.0

    F
    Participant: Non-receptor tyrosine-protein kinase TYK2

    Participant: Non-receptor tyrosine-protein kinase TYK2

    Accession: EBI-21621140

    Name: EBI-1383454

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Non-receptor tyrosine-protein kinase TYK2

    Participant: Non-receptor tyrosine-protein kinase TYK2

    Accession: EBI-21621140

    Name: EBI-1383454

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99927867110093305
    Non-specific binding CompPASS-Plus score: 7.2132886993913898E-4
    False-positive CompPASS-Plus score: 2.9127972152222603E-11

    13
    EBI-456291
     logo
    F-box protein Skp2
    Cyclin-A/CDK2-associated protein p45
    p45skp2

    [+3]
    S-phase kinase-associated protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: S-phase kinase-associated protein 2

    Participant: S-phase kinase-associated protein 2

    Accession: EBI-21621146

    Name: EBI-456291

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: S-phase kinase-associated protein 2

    Participant: S-phase kinase-associated protein 2

    Accession: EBI-21621146

    Name: EBI-456291

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: S-phase kinase-associated protein 2

    Participant: S-phase kinase-associated protein 2

    Accession: EBI-21621146

    Name: EBI-456291

    Stoichiometry: 0.0

    F
    Participant: S-phase kinase-associated protein 2

    Participant: S-phase kinase-associated protein 2

    Accession: EBI-21621146

    Name: EBI-456291

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: S-phase kinase-associated protein 2

    Participant: S-phase kinase-associated protein 2

    Accession: EBI-21621146

    Name: EBI-456291

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.98640970622031099
    Non-specific binding CompPASS-Plus score: 1.3590291490742701E-2
    False-positive CompPASS-Plus score: 2.28894644380451E-9

    14
    EBI-2515586
     logo
    TARBP1
    TRM3
    TRP185

    [+2]
    Probable methyltransferase TARBP1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Probable methyltransferase TARBP1

    Participant: Probable methyltransferase TARBP1

    Accession: EBI-21621152

    Name: EBI-2515586

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Probable methyltransferase TARBP1

    Participant: Probable methyltransferase TARBP1

    Accession: EBI-21621152

    Name: EBI-2515586

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Probable methyltransferase TARBP1

    Participant: Probable methyltransferase TARBP1

    Accession: EBI-21621152

    Name: EBI-2515586

    Stoichiometry: 0.0

    F
    Participant: Probable methyltransferase TARBP1

    Participant: Probable methyltransferase TARBP1

    Accession: EBI-21621152

    Name: EBI-2515586

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Probable methyltransferase TARBP1

    Participant: Probable methyltransferase TARBP1

    Accession: EBI-21621152

    Name: EBI-2515586

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.96710108974711695
    Non-specific binding CompPASS-Plus score: 3.2898910242771001E-2
    False-positive CompPASS-Plus score: 1.01123501676496E-11

    15
    EBI-21556035
     logo
    MTMR1
    Isoform 1A of Myotubularin-related protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Isoform 1A of Myotubularin-related protein 1

    Participant: Isoform 1A of Myotubularin-related protein 1

    Accession: EBI-21621158

    Name: EBI-21556035

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Isoform 1A of Myotubularin-related protein 1

    Participant: Isoform 1A of Myotubularin-related protein 1

    Accession: EBI-21621158

    Name: EBI-21556035

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Isoform 1A of Myotubularin-related protein 1

    Participant: Isoform 1A of Myotubularin-related protein 1

    Accession: EBI-21621158

    Name: EBI-21556035

    Stoichiometry: 0.0

    F
    Participant: Isoform 1A of Myotubularin-related protein 1

    Participant: Isoform 1A of Myotubularin-related protein 1

    Accession: EBI-21621158

    Name: EBI-21556035

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Isoform 1A of Myotubularin-related protein 1

    Participant: Isoform 1A of Myotubularin-related protein 1

    Accession: EBI-21621158

    Name: EBI-21556035

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99998636055744505
    Non-specific binding CompPASS-Plus score: 1.36394420023256E-5
    False-positive CompPASS-Plus score: 5.5300574333469601E-13

    16
    EBI-749713
     logo
    E2F dimerization partner 1
    DRTF1-polypeptide 1
    TFDP1

    [+1]
    Transcription factor Dp-1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Transcription factor Dp-1

    Participant: Transcription factor Dp-1

    Accession: EBI-21621164

    Name: EBI-749713

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Transcription factor Dp-1

    Participant: Transcription factor Dp-1

    Accession: EBI-21621164

    Name: EBI-749713

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Transcription factor Dp-1

    Participant: Transcription factor Dp-1

    Accession: EBI-21621164

    Name: EBI-749713

    Stoichiometry: 0.0

    F
    Participant: Transcription factor Dp-1

    Participant: Transcription factor Dp-1

    Accession: EBI-21621164

    Name: EBI-749713

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Transcription factor Dp-1

    Participant: Transcription factor Dp-1

    Accession: EBI-21621164

    Name: EBI-749713

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99980891445328002
    Non-specific binding CompPASS-Plus score: 1.79544702097896E-4
    False-positive CompPASS-Plus score: 1.15408446216753E-5

    17
    EBI-21621068
     logo
    E2F5
    Isoform 2 of Transcription factor E2F5
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Isoform 2 of Transcription factor E2F5

    Participant: Isoform 2 of Transcription factor E2F5

    Accession: EBI-21621170

    Name: EBI-21621068

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Isoform 2 of Transcription factor E2F5

    Participant: Isoform 2 of Transcription factor E2F5

    Accession: EBI-21621170

    Name: EBI-21621068

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Isoform 2 of Transcription factor E2F5

    Participant: Isoform 2 of Transcription factor E2F5

    Accession: EBI-21621170

    Name: EBI-21621068

    Stoichiometry: 0.0

    F
    Participant: Isoform 2 of Transcription factor E2F5

    Participant: Isoform 2 of Transcription factor E2F5

    Accession: EBI-21621170

    Name: EBI-21621068

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Isoform 2 of Transcription factor E2F5

    Participant: Isoform 2 of Transcription factor E2F5

    Accession: EBI-21621170

    Name: EBI-21621068

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99999951573846602
    Non-specific binding CompPASS-Plus score: 4.61845351366857E-7
    False-positive CompPASS-Plus score: 2.2416182768433301E-8

    18
    EBI-448943
     logo
    E2F4
    Transcription factor E2F4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Transcription factor E2F4

    Participant: Transcription factor E2F4

    Accession: EBI-21621176

    Name: EBI-448943

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Transcription factor E2F4

    Participant: Transcription factor E2F4

    Accession: EBI-21621176

    Name: EBI-448943

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Transcription factor E2F4

    Participant: Transcription factor E2F4

    Accession: EBI-21621176

    Name: EBI-448943

    Stoichiometry: 0.0

    F
    Participant: Transcription factor E2F4

    Participant: Transcription factor E2F4

    Accession: EBI-21621176

    Name: EBI-448943

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Transcription factor E2F4

    Participant: Transcription factor E2F4

    Accession: EBI-21621176

    Name: EBI-448943

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99980079812969103
    Non-specific binding CompPASS-Plus score: 1.48058358800077E-5
    False-positive CompPASS-Plus score: 1.8439603442881299E-4

    19
    EBI-2562802
     logo
    HBV DNAPTP1-transactivated protein B
    C17orf68
    Conserved telomere maintenance component 1

    [+1]
    CST complex subunit CTC1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: CST complex subunit CTC1

    Participant: CST complex subunit CTC1

    Accession: EBI-21621182

    Name: EBI-2562802

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: CST complex subunit CTC1

    Participant: CST complex subunit CTC1

    Accession: EBI-21621182

    Name: EBI-2562802

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: CST complex subunit CTC1

    Participant: CST complex subunit CTC1

    Accession: EBI-21621182

    Name: EBI-2562802

    Stoichiometry: 0.0

    F
    Participant: CST complex subunit CTC1

    Participant: CST complex subunit CTC1

    Accession: EBI-21621182

    Name: EBI-2562802

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: CST complex subunit CTC1

    Participant: CST complex subunit CTC1

    Accession: EBI-21621182

    Name: EBI-2562802

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.99994644176552305
    Non-specific binding CompPASS-Plus score: 5.3558227522289303E-5
    False-positive CompPASS-Plus score: 6.95482086233945E-12

    20
    EBI-1996072
     logo
    KLHL22
    Kelch-like protein 22
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-21621188

    Name: EBI-1996072

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    -

    P
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-21621188

    Name: EBI-1996072

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-21621188

    Name: EBI-1996072

    Stoichiometry: 0.0

    F
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-21621188

    Name: EBI-1996072

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kelch-like protein 22

    Participant: Kelch-like protein 22

    Accession: EBI-21621188

    Name: EBI-1996072

    Confidences:

    Type
    Value
    Specific binding CompPASS-Plus score: 0.97773438642530996
    Non-specific binding CompPASS-Plus score: 2.2265613574694001E-2
    False-positive CompPASS-Plus score: 5.8239424393774003E-25


    Graphical Representation of Experimental Features