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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 26496610

Journal: Cell

Year of Publication: 2015

Title: A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Author List: Hein MY., Hubner NC., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak IA., Weisswange I., Mansfeld J., Buchholz F., Hyman AA., Mann M.

Cross References:

Experiment (1323 interactions)

Accession: EBI-10990999

Name: hein-2015-2

Host organism: Homo sapiens epitheloid cervix carcinoma cells

Organism: Homo sapiens epitheloid cervix carcinoma cells

Accession: EBI-307614

Name: human-hela

Description: Homo sapiens epitheloid cervix carcinoma cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
Author confidence calculation Protein identifications as obtained from MS spectra processing were filtered, removing hits to the reverse decoy database as well as proteins only identified by modified peptides. It was required that each protein be quantified in all replicates from the AP-MS samples of at least one cell line. Protein LFQ intensities were logarithmized and missing values imputed by values simulating noise around the detection limit. For each protein, a non-parametric method was used to select a subset of samples that provide a distribution of background intensities for this protein. This subset was used first to normalize all protein intensities to represent relative enrichment, and then to serve as the control group for a two-tailed Welch’s t test. Specific outliers in the volcano plots of logarithmized p values against enrichments were determined by an approach making use of the asymmetry in the outlier population (see url links for each interaction). Two cut-offs of different stringencies, representing 1 and 5% of enrichment false discovery rate (FDR), respectively, were used. Correlation coefficients between the intensity profiles of interacting proteins were calculated as additional quality parameters. Enrichment FDR (classes A, B and C) and profile correlation (modifier + or –) define the confidence class of an interaction (see author assigned scores). Relative abundance and interaction stoichiometry estimations: Estimating interaction stoichiometries requires the comparison of the amounts of different proteins relative to each other in one IP. To this end, the authors first subtracted the median intensity across all samples to account for the proportion due to unspecific binding. Then LFQ intensities were divided by the number of theoretically observable peptides for this protein. This corrects for biases introduced by different lengths of the protein sequences and the frequency and distribution of proteolytic cleavage sites. Finally, interaction stoichiometries were expressed relative to the bait protein. Cellular copy numbers and relative abundances were calculated using a similar approach on the whole proteome data and brought to absolute scale by normalization to a total protein amount of 200 pg in a cell volume of 1 pl for a HeLa cell.
imex curation
hein@biochem.mpg.de,mmann@biochem.mpg.de
09-06-2015: Submitted by Marco Hein, Max Planck Institute of Biochemistry, Martinsried.
Only protein-protein interactions
-
PAM-SILAC experiments mentioned in the text and summarized in figure 5 were not added since the authors stated that the SILAC data just confirmed the large screening results for a set of selected baits and did not provide further detail on the interactions. The cell lines tested with PAM-SILAC were MCP_ky_0002211 (interaction id EBI-11003881), MCP_ky_0006158 (interaction id EBI-11131339) and MCP_ky_0003099 (interaction id EBI-11029579).

Interaction

Accession: EBI-11119785

Name: nes-add1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Suppl. table S2. For bait details see supp. table S1
Cell line id: MCP_ky_0005822

Participants (41)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp123pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp123pp
1
EBI-10966836
 logo
NES
Nbla00170
Nestin
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Nestin

Participant: Nestin

Accession: EBI-11119968

Name: EBI-10966836

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: Nestin

Participant: Nestin

Accession: EBI-11119968

Name: EBI-10966836

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Nestin

Participant: Nestin

Accession: EBI-11119968

Name: EBI-10966836

Stoichiometry: 0.0

F
Participant: Nestin

Participant: Nestin

Accession: EBI-11119968

Name: EBI-10966836

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
nflap tag
  • n-n
  • A
    Feature: EBI-11119996

    Feature: nflap tag

    Accession: EBI-11119996

    Name: nflap tag

    Annotations:

    Topic
    Text
    This tag was formed by the concatentation of the following sub-sequences: GFP,PreScission protease cleavage site,S epitope,TEV cleavage site,flag


    C
    Participant: Nestin

    Participant: Nestin

    Accession: EBI-11119968

    Name: EBI-10966836

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-354047
     logo
    EIF3I
    TRIP1
    EIF3S2

    [+4]
    Eukaryotic translation initiation factor 3 subunit I
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Eukaryotic translation initiation factor 3 subunit I

    Participant: Eukaryotic translation initiation factor 3 subunit I

    Accession: EBI-11119793

    Name: EBI-354047

    Annotations:

    P
    Participant: Eukaryotic translation initiation factor 3 subunit I

    Participant: Eukaryotic translation initiation factor 3 subunit I

    Accession: EBI-11119793

    Name: EBI-354047

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.179
    10
    -5
    0.0
    3.027
    10
    2
    0.0


    S
    Participant: Eukaryotic translation initiation factor 3 subunit I

    Participant: Eukaryotic translation initiation factor 3 subunit I

    Accession: EBI-11119793

    Name: EBI-354047

    Stoichiometry: 0.0

    F
    Participant: Eukaryotic translation initiation factor 3 subunit I

    Participant: Eukaryotic translation initiation factor 3 subunit I

    Accession: EBI-11119793

    Name: EBI-354047

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Eukaryotic translation initiation factor 3 subunit I

    Participant: Eukaryotic translation initiation factor 3 subunit I

    Accession: EBI-11119793

    Name: EBI-354047

    Confidences:

    Type
    Value
    B

    3
    EBI-487145
     logo
    Archvillin
    p205/p250
    SVIL
    Supervillin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Supervillin

    Participant: Supervillin

    Accession: EBI-11119798

    Name: EBI-487145

    Annotations:

    P
    Participant: Supervillin

    Participant: Supervillin

    Accession: EBI-11119798

    Name: EBI-487145

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    4.35
    10
    -4
    0.0
    1.214
    10
    1
    0.0


    S
    Participant: Supervillin

    Participant: Supervillin

    Accession: EBI-11119798

    Name: EBI-487145

    Stoichiometry: 0.0

    F
    Participant: Supervillin

    Participant: Supervillin

    Accession: EBI-11119798

    Name: EBI-487145

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Supervillin

    Participant: Supervillin

    Accession: EBI-11119798

    Name: EBI-487145

    Confidences:

    Type
    Value
    B-

    4
    EBI-2115327
     logo
    RRP9
    RNU3IP2
    U355K

    [+2]
    U3 small nucleolar RNA-interacting protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: U3 small nucleolar RNA-interacting protein 2

    Participant: U3 small nucleolar RNA-interacting protein 2

    Accession: EBI-11119803

    Name: EBI-2115327

    Annotations:

    P
    Participant: U3 small nucleolar RNA-interacting protein 2

    Participant: U3 small nucleolar RNA-interacting protein 2

    Accession: EBI-11119803

    Name: EBI-2115327

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    4.014
    10
    -5
    0.0
    4.057
    10
    1
    0.0


    S
    Participant: U3 small nucleolar RNA-interacting protein 2

    Participant: U3 small nucleolar RNA-interacting protein 2

    Accession: EBI-11119803

    Name: EBI-2115327

    Stoichiometry: 0.0

    F
    Participant: U3 small nucleolar RNA-interacting protein 2

    Participant: U3 small nucleolar RNA-interacting protein 2

    Accession: EBI-11119803

    Name: EBI-2115327

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: U3 small nucleolar RNA-interacting protein 2

    Participant: U3 small nucleolar RNA-interacting protein 2

    Accession: EBI-11119803

    Name: EBI-2115327

    Confidences:

    Type
    Value
    B-

    5
    EBI-11119789
     logo
    GPATCH4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-11119808

    Name: EBI-11119789

    Annotations:

    Topic
    Text
    Missing cellular copy number precludes calculation of relative abundance.
    A+

    P
    Participant:

    Participant:

    Accession: EBI-11119808

    Name: EBI-11119789

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.053
    10
    -4
    0.0


    S
    Participant:

    Participant:

    Accession: EBI-11119808

    Name: EBI-11119789

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-11119808

    Name: EBI-11119789

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-11119808

    Name: EBI-11119789

    Confidences:

    Type
    Value
    A+

    6
    EBI-2512975
     logo
    AMBRA1
    KIAA1736
    Activating molecule in BECN1-regulated autophagy protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Accession: EBI-11119813

    Name: EBI-2512975

    Annotations:

    P
    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Accession: EBI-11119813

    Name: EBI-2512975

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.146
    10
    -6
    0.0
    1.971
    10
    0
    0.0


    S
    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Accession: EBI-11119813

    Name: EBI-2512975

    Stoichiometry: 0.0

    F
    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Accession: EBI-11119813

    Name: EBI-2512975

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Participant: Activating molecule in BECN1-regulated autophagy protein 1

    Accession: EBI-11119813

    Name: EBI-2512975

    Confidences:

    Type
    Value
    B-

    7
    EBI-11030777
     logo
    ADDA
    Erythrocyte adducin subunit alpha
    ADD1
    Alpha-adducin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Alpha-adducin

    Participant: Alpha-adducin

    Accession: EBI-11119818

    Name: EBI-11030777

    Annotations:

    P
    Participant: Alpha-adducin

    Participant: Alpha-adducin

    Accession: EBI-11119818

    Name: EBI-11030777

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.221
    10
    -5
    0.0
    4.477
    10
    0
    0.0


    S
    Participant: Alpha-adducin

    Participant: Alpha-adducin

    Accession: EBI-11119818

    Name: EBI-11030777

    Stoichiometry: 0.0

    F
    Participant: Alpha-adducin

    Participant: Alpha-adducin

    Accession: EBI-11119818

    Name: EBI-11030777

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Alpha-adducin

    Participant: Alpha-adducin

    Accession: EBI-11119818

    Name: EBI-11030777

    Confidences:

    Type
    Value
    B-

    8
    EBI-2556886
     logo
    IDE
    Insulin protease
    Insulysin

    [+1]
    Insulin-degrading enzyme
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Insulin-degrading enzyme

    Participant: Insulin-degrading enzyme

    Accession: EBI-11119823

    Name: EBI-2556886

    Annotations:

    P
    Participant: Insulin-degrading enzyme

    Participant: Insulin-degrading enzyme

    Accession: EBI-11119823

    Name: EBI-2556886

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    3.256
    10
    -4
    0.0
    9.458
    10
    1
    0.0


    S
    Participant: Insulin-degrading enzyme

    Participant: Insulin-degrading enzyme

    Accession: EBI-11119823

    Name: EBI-2556886

    Stoichiometry: 0.0

    F
    Participant: Insulin-degrading enzyme

    Participant: Insulin-degrading enzyme

    Accession: EBI-11119823

    Name: EBI-2556886

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Insulin-degrading enzyme

    Participant: Insulin-degrading enzyme

    Accession: EBI-11119823

    Name: EBI-2556886

    Confidences:

    Type
    Value
    A+

    9
    EBI-351549
     logo
    FLII
    FLIL
    Protein flightless-1 homolog
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein flightless-1 homolog

    Participant: Protein flightless-1 homolog

    Accession: EBI-11119828

    Name: EBI-351549

    Annotations:

    P
    Participant: Protein flightless-1 homolog

    Participant: Protein flightless-1 homolog

    Accession: EBI-11119828

    Name: EBI-351549

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.115
    10
    -4
    0.0
    5.993
    10
    1
    0.0


    S
    Participant: Protein flightless-1 homolog

    Participant: Protein flightless-1 homolog

    Accession: EBI-11119828

    Name: EBI-351549

    Stoichiometry: 0.0

    F
    Participant: Protein flightless-1 homolog

    Participant: Protein flightless-1 homolog

    Accession: EBI-11119828

    Name: EBI-351549

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein flightless-1 homolog

    Participant: Protein flightless-1 homolog

    Accession: EBI-11119828

    Name: EBI-351549

    Confidences:

    Type
    Value
    B-

    10
    EBI-10902237
     logo
    RPL10
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-11119833

    Name: EBI-10902237

    Annotations:

    P
    Participant:

    Participant:

    Accession: EBI-11119833

    Name: EBI-10902237

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.384
    10
    -3
    0.0
    1.054
    10
    2
    0.0


    S
    Participant:

    Participant:

    Accession: EBI-11119833

    Name: EBI-10902237

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-11119833

    Name: EBI-10902237

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-11119833

    Name: EBI-10902237

    Confidences:

    Type
    Value
    A

    11
    EBI-296047
     logo
    HSP90AA1
    HSP90A
    HSPC1

    [+4]
    Heat shock protein HSP 90-alpha
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Heat shock protein HSP 90-alpha

    Participant: Heat shock protein HSP 90-alpha

    Accession: EBI-11119838

    Name: EBI-296047

    Annotations:

    P
    Participant: Heat shock protein HSP 90-alpha

    Participant: Heat shock protein HSP 90-alpha

    Accession: EBI-11119838

    Name: EBI-296047

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.596
    10
    -4
    0.0
    1.694
    10
    3
    0.0


    S
    Participant: Heat shock protein HSP 90-alpha

    Participant: Heat shock protein HSP 90-alpha

    Accession: EBI-11119838

    Name: EBI-296047

    Stoichiometry: 0.0

    F
    Participant: Heat shock protein HSP 90-alpha

    Participant: Heat shock protein HSP 90-alpha

    Accession: EBI-11119838

    Name: EBI-296047

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Heat shock protein HSP 90-alpha

    Participant: Heat shock protein HSP 90-alpha

    Accession: EBI-11119838

    Name: EBI-296047

    Confidences:

    Type
    Value
    B-

    12
    EBI-356635
     logo
    HADHB
    MSTP029
    TP-beta
    Trifunctional enzyme subunit beta, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Accession: EBI-11119843

    Name: EBI-356635

    Annotations:

    P
    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Accession: EBI-11119843

    Name: EBI-356635

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    6.204
    10
    -5
    0.0
    1.845
    10
    2
    0.0


    S
    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Accession: EBI-11119843

    Name: EBI-356635

    Stoichiometry: 0.0

    F
    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Accession: EBI-11119843

    Name: EBI-356635

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Participant: Trifunctional enzyme subunit beta, mitochondrial

    Accession: EBI-11119843

    Name: EBI-356635

    Confidences:

    Type
    Value
    B-

    13
    EBI-356297
     logo
    GART
    PRGS
    PGFT
    Trifunctional purine biosynthetic protein adenosine-3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11119848

    Name: EBI-356297

    Annotations:

    P
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11119848

    Name: EBI-356297

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.863
    10
    -5
    0.0
    3.22
    10
    2
    0.0


    S
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11119848

    Name: EBI-356297

    Stoichiometry: 0.0

    F
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11119848

    Name: EBI-356297

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11119848

    Name: EBI-356297

    Confidences:

    Type
    Value
    A-

    14
    EBI-1059012
     logo
    CEP162
    C6orf84
    KIAA1009

    [+2]
    Centrosomal protein of 162 kDa
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Centrosomal protein of 162 kDa

    Participant: Centrosomal protein of 162 kDa

    Accession: EBI-11119853

    Name: EBI-1059012

    Annotations:

    P
    Participant: Centrosomal protein of 162 kDa

    Participant: Centrosomal protein of 162 kDa

    Accession: EBI-11119853

    Name: EBI-1059012

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.646
    10
    -5
    0.0
    6.851
    10
    -2
    0.0


    S
    Participant: Centrosomal protein of 162 kDa

    Participant: Centrosomal protein of 162 kDa

    Accession: EBI-11119853

    Name: EBI-1059012

    Stoichiometry: 0.0

    F
    Participant: Centrosomal protein of 162 kDa

    Participant: Centrosomal protein of 162 kDa

    Accession: EBI-11119853

    Name: EBI-1059012

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Centrosomal protein of 162 kDa

    Participant: Centrosomal protein of 162 kDa

    Accession: EBI-11119853

    Name: EBI-1059012

    Confidences:

    Type
    Value
    B-

    15
    EBI-713484
     logo
    SLC35F6
    ANT2-binding protein
    C2orf18

    [+2]
    Solute carrier family 35 member F6
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Solute carrier family 35 member F6

    Participant: Solute carrier family 35 member F6

    Accession: EBI-11119858

    Name: EBI-713484

    Annotations:

    P
    Participant: Solute carrier family 35 member F6

    Participant: Solute carrier family 35 member F6

    Accession: EBI-11119858

    Name: EBI-713484

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    6.745
    10
    -5
    0.0
    2.842
    10
    0
    0.0


    S
    Participant: Solute carrier family 35 member F6

    Participant: Solute carrier family 35 member F6

    Accession: EBI-11119858

    Name: EBI-713484

    Stoichiometry: 0.0

    F
    Participant: Solute carrier family 35 member F6

    Participant: Solute carrier family 35 member F6

    Accession: EBI-11119858

    Name: EBI-713484

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Solute carrier family 35 member F6

    Participant: Solute carrier family 35 member F6

    Accession: EBI-11119858

    Name: EBI-713484

    Confidences:

    Type
    Value
    B-

    16
    EBI-355145
     logo
    POLRMT
    DNA-directed RNA polymerase, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DNA-directed RNA polymerase, mitochondrial

    Participant: DNA-directed RNA polymerase, mitochondrial

    Accession: EBI-11119863

    Name: EBI-355145

    Annotations:

    P
    Participant: DNA-directed RNA polymerase, mitochondrial

    Participant: DNA-directed RNA polymerase, mitochondrial

    Accession: EBI-11119863

    Name: EBI-355145

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.583
    10
    -4
    0.0
    5.499
    10
    0
    0.0


    S
    Participant: DNA-directed RNA polymerase, mitochondrial

    Participant: DNA-directed RNA polymerase, mitochondrial

    Accession: EBI-11119863

    Name: EBI-355145

    Stoichiometry: 0.0

    F
    Participant: DNA-directed RNA polymerase, mitochondrial

    Participant: DNA-directed RNA polymerase, mitochondrial

    Accession: EBI-11119863

    Name: EBI-355145

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DNA-directed RNA polymerase, mitochondrial

    Participant: DNA-directed RNA polymerase, mitochondrial

    Accession: EBI-11119863

    Name: EBI-355145

    Confidences:

    Type
    Value
    B-

    17
    EBI-353844
     logo
    VIM
    Vimentin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Vimentin

    Participant: Vimentin

    Accession: EBI-11119868

    Name: EBI-353844

    Annotations:

    P
    Participant: Vimentin

    Participant: Vimentin

    Accession: EBI-11119868

    Name: EBI-353844

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.17
    10
    0
    0.0
    2.953
    10
    3
    0.0


    S
    Participant: Vimentin

    Participant: Vimentin

    Accession: EBI-11119868

    Name: EBI-353844

    Stoichiometry: 0.0

    F
    Participant: Vimentin

    Participant: Vimentin

    Accession: EBI-11119868

    Name: EBI-353844

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Vimentin

    Participant: Vimentin

    Accession: EBI-11119868

    Name: EBI-353844

    Confidences:

    Type
    Value
    A-

    18
    EBI-10986851
     logo
    LAS1L
    Protein LAS1 homolog
    MSTP060
    Ribosomal biogenesis protein LAS1L
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ribosomal biogenesis protein LAS1L

    Participant: Ribosomal biogenesis protein LAS1L

    Accession: EBI-11119873

    Name: EBI-10986851

    Annotations:

    P
    Participant: Ribosomal biogenesis protein LAS1L

    Participant: Ribosomal biogenesis protein LAS1L

    Accession: EBI-11119873

    Name: EBI-10986851

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.632
    10
    -4
    0.0
    4.813
    10
    1
    0.0


    S
    Participant: Ribosomal biogenesis protein LAS1L

    Participant: Ribosomal biogenesis protein LAS1L

    Accession: EBI-11119873

    Name: EBI-10986851

    Stoichiometry: 0.0

    F
    Participant: Ribosomal biogenesis protein LAS1L

    Participant: Ribosomal biogenesis protein LAS1L

    Accession: EBI-11119873

    Name: EBI-10986851

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ribosomal biogenesis protein LAS1L

    Participant: Ribosomal biogenesis protein LAS1L

    Accession: EBI-11119873

    Name: EBI-10986851

    Confidences:

    Type
    Value
    B-

    19
    EBI-9640474
     logo
    GKAP1
    GKAP42
    cGMP-dependent protein kinase-anchoring protein of 42 kDa

    [+1]
    G kinase-anchoring protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: G kinase-anchoring protein 1

    Participant: G kinase-anchoring protein 1

    Accession: EBI-11119878

    Name: EBI-9640474

    Annotations:

    P
    Participant: G kinase-anchoring protein 1

    Participant: G kinase-anchoring protein 1

    Accession: EBI-11119878

    Name: EBI-9640474

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.568
    10
    -5
    0.0
    1.71
    10
    0
    0.0


    S
    Participant: G kinase-anchoring protein 1

    Participant: G kinase-anchoring protein 1

    Accession: EBI-11119878

    Name: EBI-9640474

    Stoichiometry: 0.0

    F
    Participant: G kinase-anchoring protein 1

    Participant: G kinase-anchoring protein 1

    Accession: EBI-11119878

    Name: EBI-9640474

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: G kinase-anchoring protein 1

    Participant: G kinase-anchoring protein 1

    Accession: EBI-11119878

    Name: EBI-9640474

    Confidences:

    Type
    Value
    B

    20
    EBI-353389
     logo
    IMPDH2
    IMPD2
    IMPDH-II
    Inosine-5'-monophosphate dehydrogenase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Accession: EBI-11119883

    Name: EBI-353389

    Annotations:

    P
    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Accession: EBI-11119883

    Name: EBI-353389

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.242
    10
    -5
    0.0
    4.223
    10
    2
    0.0


    S
    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Accession: EBI-11119883

    Name: EBI-353389

    Stoichiometry: 0.0

    F
    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Accession: EBI-11119883

    Name: EBI-353389

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Participant: Inosine-5'-monophosphate dehydrogenase 2

    Accession: EBI-11119883

    Name: EBI-353389

    Confidences:

    Type
    Value
    B-


    Graphical Representation of Experimental Features