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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 26496610

Journal: Cell

Year of Publication: 2015

Title: A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Author List: Hein MY., Hubner NC., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak IA., Weisswange I., Mansfeld J., Buchholz F., Hyman AA., Mann M.

Cross References:

Experiment (1323 interactions)

Accession: EBI-10990999

Name: hein-2015-2

Host organism: Homo sapiens epitheloid cervix carcinoma cells

Organism: Homo sapiens epitheloid cervix carcinoma cells

Accession: EBI-307614

Name: human-hela

Description: Homo sapiens epitheloid cervix carcinoma cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0102
-
identity
pubmed
10967324
-
primary-reference
pubmed
11752590
-
primary-reference
pubmed
11805837
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Annotations:

Topic
Text
Author confidence calculation Protein identifications as obtained from MS spectra processing were filtered, removing hits to the reverse decoy database as well as proteins only identified by modified peptides. It was required that each protein be quantified in all replicates from the AP-MS samples of at least one cell line. Protein LFQ intensities were logarithmized and missing values imputed by values simulating noise around the detection limit. For each protein, a non-parametric method was used to select a subset of samples that provide a distribution of background intensities for this protein. This subset was used first to normalize all protein intensities to represent relative enrichment, and then to serve as the control group for a two-tailed Welch’s t test. Specific outliers in the volcano plots of logarithmized p values against enrichments were determined by an approach making use of the asymmetry in the outlier population (see url links for each interaction). Two cut-offs of different stringencies, representing 1 and 5% of enrichment false discovery rate (FDR), respectively, were used. Correlation coefficients between the intensity profiles of interacting proteins were calculated as additional quality parameters. Enrichment FDR (classes A, B and C) and profile correlation (modifier + or –) define the confidence class of an interaction (see author assigned scores). Relative abundance and interaction stoichiometry estimations: Estimating interaction stoichiometries requires the comparison of the amounts of different proteins relative to each other in one IP. To this end, the authors first subtracted the median intensity across all samples to account for the proportion due to unspecific binding. Then LFQ intensities were divided by the number of theoretically observable peptides for this protein. This corrects for biases introduced by different lengths of the protein sequences and the frequency and distribution of proteolytic cleavage sites. Finally, interaction stoichiometries were expressed relative to the bait protein. Cellular copy numbers and relative abundances were calculated using a similar approach on the whole proteome data and brought to absolute scale by normalization to a total protein amount of 200 pg in a cell volume of 1 pl for a HeLa cell.
imex curation
hein@biochem.mpg.de,mmann@biochem.mpg.de
09-06-2015: Submitted by Marco Hein, Max Planck Institute of Biochemistry, Martinsried.
Only protein-protein interactions
-
PAM-SILAC experiments mentioned in the text and summarized in figure 5 were not added since the authors stated that the SILAC data just confirmed the large screening results for a set of selected baits and did not provide further detail on the interactions. The cell lines tested with PAM-SILAC were MCP_ky_0002211 (interaction id EBI-11003881), MCP_ky_0006158 (interaction id EBI-11131339) and MCP_ky_0003099 (interaction id EBI-11029579).

Interaction

Accession: EBI-11060556

Name: ncbp1-ap1m1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Suppl. table S2. For bait details see supp. table S1
Cell line id: MCP_ky_0003883

Participants (30)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12pp
1
EBI-464743
 logo
NCBP1
CBP80
NCBP

[+1]
Nuclear cap-binding protein subunit 1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Nuclear cap-binding protein subunit 1

Participant: Nuclear cap-binding protein subunit 1

Accession: EBI-11060635

Name: EBI-464743

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

P
Participant: Nuclear cap-binding protein subunit 1

Participant: Nuclear cap-binding protein subunit 1

Accession: EBI-11060635

Name: EBI-464743

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Nuclear cap-binding protein subunit 1

Participant: Nuclear cap-binding protein subunit 1

Accession: EBI-11060635

Name: EBI-464743

Stoichiometry: 0.0

F
Participant: Nuclear cap-binding protein subunit 1

Participant: Nuclear cap-binding protein subunit 1

Accession: EBI-11060635

Name: EBI-464743

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
lap tag
  • c-c
  • A
    Feature: EBI-11060713

    Feature: lap tag

    Accession: EBI-11060713

    Name: lap tag

    Annotations:

    Topic
    Text
    This tag was formed by the concatentation of the following sub-sequences: TEV cleavage site,S epitope,PreScission protease cleavage site,GFP


    C
    Participant: Nuclear cap-binding protein subunit 1

    Participant: Nuclear cap-binding protein subunit 1

    Accession: EBI-11060635

    Name: EBI-464743

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-349938
     logo
    KPNA2
    RCH1
    SRP1

    [+3]
    Importin subunit alpha-1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Importin subunit alpha-1

    Participant: Importin subunit alpha-1

    Accession: EBI-11060565

    Name: EBI-349938

    Annotations:

    P
    Participant: Importin subunit alpha-1

    Participant: Importin subunit alpha-1

    Accession: EBI-11060565

    Name: EBI-349938

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.686
    10
    -2
    0.0
    1.619
    10
    0
    0.0


    S
    Participant: Importin subunit alpha-1

    Participant: Importin subunit alpha-1

    Accession: EBI-11060565

    Name: EBI-349938

    Stoichiometry: 0.0

    F
    Participant: Importin subunit alpha-1

    Participant: Importin subunit alpha-1

    Accession: EBI-11060565

    Name: EBI-349938

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Importin subunit alpha-1

    Participant: Importin subunit alpha-1

    Accession: EBI-11060565

    Name: EBI-349938

    Confidences:

    Type
    Value
    B+

    3
    EBI-356297
     logo
    GART
    PRGS
    PGFT
    Trifunctional purine biosynthetic protein adenosine-3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11060570

    Name: EBI-356297

    Annotations:

    P
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11060570

    Name: EBI-356297

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.033
    10
    -5
    0.0
    2.371
    10
    0
    0.0


    S
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11060570

    Name: EBI-356297

    Stoichiometry: 0.0

    F
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11060570

    Name: EBI-356297

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Participant: Trifunctional purine biosynthetic protein adenosine-3

    Accession: EBI-11060570

    Name: EBI-356297

    Confidences:

    Type
    Value
    B

    4
    EBI-4290634
     logo
    APOL2
    Apolipoprotein L-II
    Apolipoprotein L2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Apolipoprotein L2

    Participant: Apolipoprotein L2

    Accession: EBI-11060575

    Name: EBI-4290634

    Annotations:

    P
    Participant: Apolipoprotein L2

    Participant: Apolipoprotein L2

    Accession: EBI-11060575

    Name: EBI-4290634

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.14
    10
    -4
    0.0
    4.716
    10
    -3
    0.0


    S
    Participant: Apolipoprotein L2

    Participant: Apolipoprotein L2

    Accession: EBI-11060575

    Name: EBI-4290634

    Stoichiometry: 0.0

    F
    Participant: Apolipoprotein L2

    Participant: Apolipoprotein L2

    Accession: EBI-11060575

    Name: EBI-4290634

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Apolipoprotein L2

    Participant: Apolipoprotein L2

    Accession: EBI-11060575

    Name: EBI-4290634

    Confidences:

    Type
    Value
    B-

    5
    EBI-5280046
     logo
    B
    SRRT
    ARS2

    [+2]
    Serrate RNA effector molecule homolog
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serrate RNA effector molecule homolog

    Participant: Serrate RNA effector molecule homolog

    Accession: EBI-11060580

    Name: EBI-5280046

    Annotations:

    P
    Participant: Serrate RNA effector molecule homolog

    Participant: Serrate RNA effector molecule homolog

    Accession: EBI-11060580

    Name: EBI-5280046

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    3.158
    10
    -1
    0.0
    9.472
    10
    -1
    0.0


    S
    Participant: Serrate RNA effector molecule homolog

    Participant: Serrate RNA effector molecule homolog

    Accession: EBI-11060580

    Name: EBI-5280046

    Stoichiometry: 0.0

    F
    Participant: Serrate RNA effector molecule homolog

    Participant: Serrate RNA effector molecule homolog

    Accession: EBI-11060580

    Name: EBI-5280046

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serrate RNA effector molecule homolog

    Participant: Serrate RNA effector molecule homolog

    Accession: EBI-11060580

    Name: EBI-5280046

    Confidences:

    Type
    Value
    C+

    6
    EBI-11060560
     logo
    PPRC1
    KIAA0595
    PGC-1-related coactivator
    Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Accession: EBI-11060585

    Name: EBI-11060560

    Annotations:

    P
    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Accession: EBI-11060585

    Name: EBI-11060560

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.306
    10
    -2
    0.0
    1.615
    10
    -3
    0.0


    S
    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Accession: EBI-11060585

    Name: EBI-11060560

    Stoichiometry: 0.0

    F
    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Accession: EBI-11060585

    Name: EBI-11060560

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Participant: Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    Accession: EBI-11060585

    Name: EBI-11060560

    Confidences:

    Type
    Value
    B-

    7
    EBI-10826195
     logo
    BRAT1
    BAAT1
    C7orf27

    [+1]
    BRCA1-associated ATM activator 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: BRCA1-associated ATM activator 1

    Participant: BRCA1-associated ATM activator 1

    Accession: EBI-11060590

    Name: EBI-10826195

    Annotations:

    P
    Participant: BRCA1-associated ATM activator 1

    Participant: BRCA1-associated ATM activator 1

    Accession: EBI-11060590

    Name: EBI-10826195

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.276
    10
    -5
    0.0
    2.369
    10
    -1
    0.0


    S
    Participant: BRCA1-associated ATM activator 1

    Participant: BRCA1-associated ATM activator 1

    Accession: EBI-11060590

    Name: EBI-10826195

    Stoichiometry: 0.0

    F
    Participant: BRCA1-associated ATM activator 1

    Participant: BRCA1-associated ATM activator 1

    Accession: EBI-11060590

    Name: EBI-10826195

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: BRCA1-associated ATM activator 1

    Participant: BRCA1-associated ATM activator 1

    Accession: EBI-11060590

    Name: EBI-10826195

    Confidences:

    Type
    Value
    B-

    8
    EBI-347721
     logo
    NELFB
    COBRA1
    Cofactor of BRCA1

    [+1]
    Negative elongation factor B
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Negative elongation factor B

    Participant: Negative elongation factor B

    Accession: EBI-11060595

    Name: EBI-347721

    Annotations:

    P
    Participant: Negative elongation factor B

    Participant: Negative elongation factor B

    Accession: EBI-11060595

    Name: EBI-347721

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    5.858
    10
    -3
    0.0
    2.254
    10
    -1
    0.0


    S
    Participant: Negative elongation factor B

    Participant: Negative elongation factor B

    Accession: EBI-11060595

    Name: EBI-347721

    Stoichiometry: 0.0

    F
    Participant: Negative elongation factor B

    Participant: Negative elongation factor B

    Accession: EBI-11060595

    Name: EBI-347721

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Negative elongation factor B

    Participant: Negative elongation factor B

    Accession: EBI-11060595

    Name: EBI-347721

    Confidences:

    Type
    Value
    A-

    9
    EBI-5667190
     logo
    RNA U small nuclear RNA export adapter protein
    RNUXA
    PHAX
    Phosphorylated adapter RNA export protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Phosphorylated adapter RNA export protein

    Participant: Phosphorylated adapter RNA export protein

    Accession: EBI-11060600

    Name: EBI-5667190

    Annotations:

    P
    Participant: Phosphorylated adapter RNA export protein

    Participant: Phosphorylated adapter RNA export protein

    Accession: EBI-11060600

    Name: EBI-5667190

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.293
    10
    -1
    0.0
    2.258
    10
    -1
    0.0


    S
    Participant: Phosphorylated adapter RNA export protein

    Participant: Phosphorylated adapter RNA export protein

    Accession: EBI-11060600

    Name: EBI-5667190

    Stoichiometry: 0.0

    F
    Participant: Phosphorylated adapter RNA export protein

    Participant: Phosphorylated adapter RNA export protein

    Accession: EBI-11060600

    Name: EBI-5667190

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Phosphorylated adapter RNA export protein

    Participant: Phosphorylated adapter RNA export protein

    Accession: EBI-11060600

    Name: EBI-5667190

    Confidences:

    Type
    Value
    A-

    10
    EBI-10973855
     logo
    RPRD2
    KIAA0460
    HSPC099
    Regulation of nuclear pre-mRNA domain-containing protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Accession: EBI-11060605

    Name: EBI-10973855

    Annotations:

    P
    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Accession: EBI-11060605

    Name: EBI-10973855

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    3.09
    10
    -5
    0.0
    3.342
    10
    -1
    0.0


    S
    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Accession: EBI-11060605

    Name: EBI-10973855

    Stoichiometry: 0.0

    F
    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Accession: EBI-11060605

    Name: EBI-10973855

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Participant: Regulation of nuclear pre-mRNA domain-containing protein 2

    Accession: EBI-11060605

    Name: EBI-10973855

    Confidences:

    Type
    Value
    B-

    11
    EBI-358297
     logo
    KPNA3
    QIP2
    Karyopherin subunit alpha-3

    [+2]
    Importin subunit alpha-4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Importin subunit alpha-4

    Participant: Importin subunit alpha-4

    Accession: EBI-11060610

    Name: EBI-358297

    Annotations:

    P
    Participant: Importin subunit alpha-4

    Participant: Importin subunit alpha-4

    Accession: EBI-11060610

    Name: EBI-358297

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.395
    10
    -2
    0.0
    8.466
    10
    -1
    0.0


    S
    Participant: Importin subunit alpha-4

    Participant: Importin subunit alpha-4

    Accession: EBI-11060610

    Name: EBI-358297

    Stoichiometry: 0.0

    F
    Participant: Importin subunit alpha-4

    Participant: Importin subunit alpha-4

    Accession: EBI-11060610

    Name: EBI-358297

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Importin subunit alpha-4

    Participant: Importin subunit alpha-4

    Accession: EBI-11060610

    Name: EBI-358297

    Confidences:

    Type
    Value
    A+

    12
    EBI-356221
     logo
    GCN1
    GCN1 eIF-2-alpha kinase activator homolog
    GCN1-like protein 1

    [+4]
    eIF-2-alpha kinase activator GCN1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: eIF-2-alpha kinase activator GCN1

    Participant: eIF-2-alpha kinase activator GCN1

    Accession: EBI-11060615

    Name: EBI-356221

    Annotations:

    P
    Participant: eIF-2-alpha kinase activator GCN1

    Participant: eIF-2-alpha kinase activator GCN1

    Accession: EBI-11060615

    Name: EBI-356221

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    5.059
    10
    -3
    0.0
    1.064
    10
    0
    0.0


    S
    Participant: eIF-2-alpha kinase activator GCN1

    Participant: eIF-2-alpha kinase activator GCN1

    Accession: EBI-11060615

    Name: EBI-356221

    Stoichiometry: 0.0

    F
    Participant: eIF-2-alpha kinase activator GCN1

    Participant: eIF-2-alpha kinase activator GCN1

    Accession: EBI-11060615

    Name: EBI-356221

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: eIF-2-alpha kinase activator GCN1

    Participant: eIF-2-alpha kinase activator GCN1

    Accession: EBI-11060615

    Name: EBI-356221

    Confidences:

    Type
    Value
    B-

    13
    EBI-2515057
     logo
    NUPL2
    CG1
    NLP-1

    [+2]
    Nucleoporin-like protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nucleoporin-like protein 2

    Participant: Nucleoporin-like protein 2

    Accession: EBI-11060620

    Name: EBI-2515057

    Annotations:

    P
    Participant: Nucleoporin-like protein 2

    Participant: Nucleoporin-like protein 2

    Accession: EBI-11060620

    Name: EBI-2515057

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.294
    10
    -4
    0.0
    1.322
    10
    -1
    0.0


    S
    Participant: Nucleoporin-like protein 2

    Participant: Nucleoporin-like protein 2

    Accession: EBI-11060620

    Name: EBI-2515057

    Stoichiometry: 0.0

    F
    Participant: Nucleoporin-like protein 2

    Participant: Nucleoporin-like protein 2

    Accession: EBI-11060620

    Name: EBI-2515057

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nucleoporin-like protein 2

    Participant: Nucleoporin-like protein 2

    Accession: EBI-11060620

    Name: EBI-2515057

    Confidences:

    Type
    Value
    B

    14
    EBI-443648
     logo
    GEMIN2
    SIP1
    Component of gems 2

    [+1]
    Gem-associated protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Gem-associated protein 2

    Participant: Gem-associated protein 2

    Accession: EBI-11060625

    Name: EBI-443648

    Annotations:

    P
    Participant: Gem-associated protein 2

    Participant: Gem-associated protein 2

    Accession: EBI-11060625

    Name: EBI-443648

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.5
    10
    -3
    0.0
    3.089
    10
    -2
    0.0


    S
    Participant: Gem-associated protein 2

    Participant: Gem-associated protein 2

    Accession: EBI-11060625

    Name: EBI-443648

    Stoichiometry: 0.0

    F
    Participant: Gem-associated protein 2

    Participant: Gem-associated protein 2

    Accession: EBI-11060625

    Name: EBI-443648

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Gem-associated protein 2

    Participant: Gem-associated protein 2

    Accession: EBI-11060625

    Name: EBI-443648

    Confidences:

    Type
    Value
    A

    15
    EBI-11023763
     logo
    TRRAP
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-11060630

    Name: EBI-11023763

    Annotations:

    P
    Participant:

    Participant:

    Accession: EBI-11060630

    Name: EBI-11023763

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    3.333
    10
    -5
    0.0
    5.293
    10
    -2
    0.0


    S
    Participant:

    Participant:

    Accession: EBI-11060630

    Name: EBI-11023763

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-11060630

    Name: EBI-11023763

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-11060630

    Name: EBI-11023763

    Confidences:

    Type
    Value
    B-

    16
    EBI-713507
     logo
    LYAR
    PNAS-5
    Cell growth-regulating nucleolar protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cell growth-regulating nucleolar protein

    Participant: Cell growth-regulating nucleolar protein

    Accession: EBI-11060638

    Name: EBI-713507

    Annotations:

    P
    Participant: Cell growth-regulating nucleolar protein

    Participant: Cell growth-regulating nucleolar protein

    Accession: EBI-11060638

    Name: EBI-713507

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.235
    10
    -2
    0.0
    1.404
    10
    0
    0.0


    S
    Participant: Cell growth-regulating nucleolar protein

    Participant: Cell growth-regulating nucleolar protein

    Accession: EBI-11060638

    Name: EBI-713507

    Stoichiometry: 0.0

    F
    Participant: Cell growth-regulating nucleolar protein

    Participant: Cell growth-regulating nucleolar protein

    Accession: EBI-11060638

    Name: EBI-713507

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cell growth-regulating nucleolar protein

    Participant: Cell growth-regulating nucleolar protein

    Accession: EBI-11060638

    Name: EBI-713507

    Confidences:

    Type
    Value
    B-

    17
    EBI-10972895
     logo
    RSRC1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant:

    Participant:

    Accession: EBI-11060643

    Name: EBI-10972895

    Annotations:

    Topic
    Text
    Low enrichment precludes background subtraction required for interaction stoichiometry calculation.
    Missing cellular copy number precludes calculation of relative abundance.
    B-

    P
    Participant:

    Participant:

    Accession: EBI-11060643

    Name: EBI-10972895

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant:

    Participant:

    Accession: EBI-11060643

    Name: EBI-10972895

    Stoichiometry: 0.0

    F
    Participant:

    Participant:

    Accession: EBI-11060643

    Name: EBI-10972895

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant:

    Participant:

    Accession: EBI-11060643

    Name: EBI-10972895

    Confidences:

    Type
    Value
    B-

    18
    EBI-5461341
     logo
    NELFA
    WHSC2
    Wolf-Hirschhorn syndrome candidate 2 protein

    [+1]
    Negative elongation factor A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Negative elongation factor A

    Participant: Negative elongation factor A

    Accession: EBI-11060648

    Name: EBI-5461341

    Annotations:

    P
    Participant: Negative elongation factor A

    Participant: Negative elongation factor A

    Accession: EBI-11060648

    Name: EBI-5461341

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    1.085
    10
    -3
    0.0
    2.127
    10
    -1
    0.0


    S
    Participant: Negative elongation factor A

    Participant: Negative elongation factor A

    Accession: EBI-11060648

    Name: EBI-5461341

    Stoichiometry: 0.0

    F
    Participant: Negative elongation factor A

    Participant: Negative elongation factor A

    Accession: EBI-11060648

    Name: EBI-5461341

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Negative elongation factor A

    Participant: Negative elongation factor A

    Accession: EBI-11060648

    Name: EBI-5461341

    Confidences:

    Type
    Value
    A

    19
    EBI-464729
     logo
    20 kDa nuclear cap-binding protein
    NCBP 20 kDa subunit
    NCBP-interacting protein 1

    [+4]
    Nuclear cap-binding protein subunit 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear cap-binding protein subunit 2

    Participant: Nuclear cap-binding protein subunit 2

    Accession: EBI-11060653

    Name: EBI-464729

    Annotations:

    P
    Participant: Nuclear cap-binding protein subunit 2

    Participant: Nuclear cap-binding protein subunit 2

    Accession: EBI-11060653

    Name: EBI-464729

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    7.608
    10
    -1
    0.0
    1.342
    10
    0
    0.0


    S
    Participant: Nuclear cap-binding protein subunit 2

    Participant: Nuclear cap-binding protein subunit 2

    Accession: EBI-11060653

    Name: EBI-464729

    Stoichiometry: 0.0

    F
    Participant: Nuclear cap-binding protein subunit 2

    Participant: Nuclear cap-binding protein subunit 2

    Accession: EBI-11060653

    Name: EBI-464729

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear cap-binding protein subunit 2

    Participant: Nuclear cap-binding protein subunit 2

    Accession: EBI-11060653

    Name: EBI-464729

    Confidences:

    Type
    Value
    A+

    20
    EBI-356983
     logo
    UBL4A
    GDX
    DXS254E

    [+2]
    Ubiquitin-like protein 4A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ubiquitin-like protein 4A

    Participant: Ubiquitin-like protein 4A

    Accession: EBI-11060658

    Name: EBI-356983

    Annotations:

    P
    Participant: Ubiquitin-like protein 4A

    Participant: Ubiquitin-like protein 4A

    Accession: EBI-11060658

    Name: EBI-356983

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    2.657
    10
    -3
    0.0
    4.16
    10
    -1
    0.0


    S
    Participant: Ubiquitin-like protein 4A

    Participant: Ubiquitin-like protein 4A

    Accession: EBI-11060658

    Name: EBI-356983

    Stoichiometry: 0.0

    F
    Participant: Ubiquitin-like protein 4A

    Participant: Ubiquitin-like protein 4A

    Accession: EBI-11060658

    Name: EBI-356983

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ubiquitin-like protein 4A

    Participant: Ubiquitin-like protein 4A

    Accession: EBI-11060658

    Name: EBI-356983

    Confidences:

    Type
    Value
    B-


    Graphical Representation of Experimental Features