{"systematicName":"CSG2:SUR1","synonyms":["SUR1:CSG2","CSG1-CSG2","Csg1p-Csg2p"],"functions":["Catalyzes the addition of mannosyl to phosphorylinositol ceramide, and essential step in the synthesis of mannosylinositol phosphorylceramide. Function in the Golgi. Preferentially active against IPC-B and IPC-C in comparison with Mannosyl phosphorylinositol ceramide synthase CSH1-CSG2 (CPX-1740)."],"properties":[],"ac":"EBI-2477009","complexAc":"CPX-1739","name":"Mannosyl phosphorylinositol ceramide synthase SUR1-CSG2","species":"Saccharomyces cerevisiae; 559292","ligands":[],"complexAssemblies":[],"diseases":[],"participants":[{"interactorAC":"EBI-2477014","identifier":"P33300","identifierLink":"https://www.uniprot.org/uniprotkb/P33300/entry","name":"SUR1","description":"Mannosyl phosphorylinositol ceramide synthase SUR1","stochiometry":null,"bioRole":"unspecified role","bioRoleMI":"MI:0499","bioRoleDefinition":"Role not specified or not applicable to the data.","interactorType":"protein","interactorTypeMI":"MI:0326","interactorTypeDefinition":"A linear polymer of amino acids joined by peptide bonds in a specific sequence.","linkedFeatures":[{"featureAc":"EBI-25818429","participantId":"P35206","name":"sur1 binding region","featureType":"binding region","featureTypeMI":"MI:0117","featureTypeDefinition":"A region of a molecule or a component of a complex identified as being involved in an interaction. This may or may not be a region of the molecule in direct contact with the interacting partner.","featureTypeUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0117","featureRole":null,"featureRoleMI":null,"featureRoleDefinition":null,"featureRoleUrl":null,"ranges":["?-?"],"linkedFeatures":["EBI-25818427"],"crossReferences":[]}],"otherFeatures":[]},{"interactorAC":"EBI-2477013","identifier":"P35206","identifierLink":"https://www.uniprot.org/uniprotkb/P35206/entry","name":"CSG2","description":"Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2","stochiometry":null,"bioRole":"unspecified role","bioRoleMI":"MI:0499","bioRoleDefinition":"Role not specified or not applicable to the data.","interactorType":"protein","interactorTypeMI":"MI:0326","interactorTypeDefinition":"A linear polymer of amino acids joined by peptide bonds in a specific sequence.","linkedFeatures":[{"featureAc":"EBI-25818427","participantId":"P33300","name":"csg2 binding region","featureType":"binding region","featureTypeMI":"MI:0117","featureTypeDefinition":"A region of a molecule or a component of a complex identified as being involved in an interaction. This may or may not be a region of the molecule in direct contact with the interacting partner.","featureTypeUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0117","featureRole":null,"featureRoleMI":null,"featureRoleDefinition":null,"featureRoleUrl":null,"ranges":["?-?"],"linkedFeatures":["EBI-25818429"],"crossReferences":[]}],"otherFeatures":[]}],"crossReferences":[{"database":"intact","qualifier":"Experimental evidence that interaction occurs","identifier":"EBI-2476987","description":null,"searchURL":"http://www.ebi.ac.uk/intact/query/EBI-2476987","dbMI":"MI:0469","qualifierMI":null,"dbdefinition":"INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.\n","qualifierDefinition":null,"qualifierUrl":null},{"database":"evidence ontology","qualifier":null,"identifier":"ECO:0000353","description":null,"searchURL":"http://www.ebi.ac.uk/ols/ontologies/ECO/terms?obo_id=ECO:0000353","dbMI":"MI:1331","qualifierMI":null,"dbdefinition":"The Evidence Ontology (ECO) describes types of scientific evidence within the realm of biological research that can arise from laboratory experiments, computational methods, manual literature curation, and other means.","qualifierDefinition":null,"qualifierUrl":null},{"database":"gene ontology","qualifier":"molecular function","identifier":"GO:0000030","description":"mannosyltransferase activity","searchURL":"https://www.ebi.ac.uk/QuickGO/term/GO:0000030","dbMI":"MI:0448","qualifierMI":"MI:0355","dbdefinition":"The objective of Gene Ontology (GO) is to provide controlled vocabularies for the description of the molecular function, biological process and cellular component of gene products.","qualifierDefinition":"Cross reference pointing to a Gene Ontology -'molecular function' term.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0355"},{"database":"pubmed","qualifier":"additional information","identifier":"12954640","description":null,"searchURL":"http://europepmc.org/abstract/MED/12954640","dbMI":"MI:0446","qualifierMI":"MI:0361","dbdefinition":"PubMed is designed to provide access to citations from biomedical literature. The data can be found at both NCBI PubMed and Europe PubMed Central. \n\nhttp://europepmc.org","qualifierDefinition":"Related object within the same database or pointing to an external database.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0361"},{"database":"gene ontology","qualifier":"cellular component","identifier":"GO:0031501","description":"mannosyltransferase complex","searchURL":"https://www.ebi.ac.uk/QuickGO/term/GO:0031501","dbMI":"MI:0448","qualifierMI":"MI:0354","dbdefinition":"The objective of Gene Ontology (GO) is to provide controlled vocabularies for the description of the molecular function, biological process and cellular component of gene products.","qualifierDefinition":"Cross reference pointing to a Gene Ontology -'cellular component' term.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0354"},{"database":"gene ontology","qualifier":"cellular component","identifier":"GO:0005794","description":"Golgi apparatus","searchURL":"https://www.ebi.ac.uk/QuickGO/term/GO:0005794","dbMI":"MI:0448","qualifierMI":"MI:0354","dbdefinition":"The objective of Gene Ontology (GO) is to provide controlled vocabularies for the description of the molecular function, biological process and cellular component of gene products.","qualifierDefinition":"Cross reference pointing to a Gene Ontology -'cellular component' term.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0354"},{"database":"gene ontology","qualifier":"biological process","identifier":"GO:0006676","description":"mannosyl diphosphorylinositol ceramide metabolic process","searchURL":"https://www.ebi.ac.uk/QuickGO/term/GO:0006676","dbMI":"MI:0448","qualifierMI":"MI:0359","dbdefinition":"The objective of Gene Ontology (GO) is to provide controlled vocabularies for the description of the molecular function, biological process and cellular component of gene products.","qualifierDefinition":"Cross reference pointing to a Gene Ontology -'cellular process' term.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0359"},{"database":"qsproteome","qualifier":"identical object in an external resource","identifier":"QS174831","description":null,"searchURL":"https://qsproteome.org/entry/QS174831","dbMI":"MI:2443","qualifierMI":"MI:0356","dbdefinition":"QSProteome is a centralized, community-driven structural biology resource that hosts over 35,000 predicted oligomeric protein complex models, covering more than 42,000 genes across multiple species. It prevents redundant modeling by allowing researchers to track existing predictions and provides clear quality metrics (pLDDT, ipTM, PAE) to assess model reliability. Each entry includes interactive 3D visualization, functional annotations, and links to databases such as BioCyc, ComplexPortal, PDB, and UniProt, integrating computational predictions with experimental data. The platform also supports community curation, enabling users to refine models and contribute to the expanding structural proteome.","qualifierDefinition":"Reference to the corresponding object in another database. Correspondence may be complete or partial.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0356"},{"database":"intenz","qualifier":"identical object in an external resource","identifier":"2.4","description":null,"searchURL":"http://www.ebi.ac.uk/intenz/query?cmd=Search&q=2.4&t=exact&fields=ec","dbMI":"MI:0585","qualifierMI":"MI:0356","dbdefinition":"IntEnz is the name for the Integrated relational Enzyme database and is the official version of the Enzyme Nomenclature. The Enzyme Nomenclature comprises recommendations of the Nomenclature Committee of the International Union of Bio chemistry and Molecular Biology (NC-IUBMB) on the nomenclature and classification of enzyme-catalysed reactions. IntEnz is supported by NC-IUBMB and contains enzyme data curated and approved by this committee. The database IntEnz is available at.","qualifierDefinition":"Reference to the corresponding object in another database. Correspondence may be complete or partial.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:0356"},{"database":"complex portal","qualifier":"complex-primary","identifier":"CPX-1739","description":null,"searchURL":"http://www.ebi.ac.uk/complexportal/complex/CPX-1739","dbMI":"MI:2279","qualifierMI":"MI:2282","dbdefinition":"The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms, entered into the IntAct molecular interaction database . Data includes protein-only complexes as well as protein-small molecule and protein-nucleic acid complexes. All complexes are derived from physical molecular interaction evidences extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background. All complexes are tagged with Evidence and Conclusion Ontology codes to indicate the type of evidence available for each entry.","qualifierDefinition":"Complex object unique primary identifier that is assigned to a complex in the Complex Portal.","qualifierUrl":"http://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI:2282"}],"institution":"IntAct","institutionURL":"http://www.ebi.ac.uk/intact","agonists":[],"antagonists":[],"comments":[],"predictedComplex":false,"evidenceType":{"identifier":"ECO:0000353","description":"physical interaction evidence","searchURL":"http://www.ebi.ac.uk/ols/ontologies/ECO/terms?obo_id=ECO:0000353","confidenceScore":5},"releaseDates":["2014-10-16"]}