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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees
(View summary and phylogenies for PF00093 - VWC)
FAM  PF00093
PID  VWC
DES  von Willebrand factor type C domain
IPR  IPR001007
ANO  20
ALN  99
AID  0.371491
APH  (((VWF_HUMAN/2257-2325:1.08745,SOG_DROME/744-803:0.67562):0.14351,(VWF_HUMAN/2431-2494:1.37851,((CEF10_CHICK/100-163:0.09482,(NOV_CHICK/106-169:0.32815,CTGF_HUMAN/103-166:0.17349):0.27111):0.32454,(SOG_DROME/102-174:0.83558,(SOG_DROME/832-898:0.92547,SOG_DROME/941-1019:0.91856):0.32456):0.64164):0.26147):0.12126):0.23122,(((CO1A1_CHICK/33-88:0.10924,CO1A1_HUMAN/40-95:0.26092):0.11901,(CO2A1_MOUSE/34-88:0.17742,CO3A1_MOUSE/33-89:0.24745):0.00000):0.33220,CO5A2_HUMAN/41-96:0.15308):0.39010,((TSP1_HUMAN/318-372:0.17903,TSP1_XENLA/321-375:0.05537):0.23131,(VWF_HUMAN/2582-2644:1.15981,(TSP2_CHICK/326-380:0.19449,(TSP2_HUMAN/320-374:0.04773,TSP2_MOUSE/320-374:0.06537):0.16585):0.25395):0.31823):0.43072);
ATP  (((VWF_HUMAN/2257-2325,SOG_DROME/744-803),(VWF_HUMAN/2431-2494,((CEF10_CHICK/100-163,(NOV_CHICK/106-169,CTGF_HUMAN/103-166)),(SOG_DROME/102-174,(SOG_DROME/832-898,SOG_DROME/941-1019))))),(((CO1A1_CHICK/33-88,CO1A1_HUMAN/40-95),(CO2A1_MOUSE/34-88,CO3A1_MOUSE/33-89)),CO5A2_HUMAN/41-96),((TSP1_HUMAN/318-372,TSP1_XENLA/321-375),(VWF_HUMAN/2582-2644,(TSP2_CHICK/326-380,(TSP2_HUMAN/320-374,TSP2_MOUSE/320-374)))));
ATL  13.6282
DNO  19
DLN  297
DID  0.47047
DPH  ((((((((CO3A1_MOUSE/33-89:0.27459,CO2A1_MOUSE/34-88:0.10059):0.06776,(CO1A1_HUMAN/40-95:0.23671,CO1A1_CHICK/33-88:0.04639):0.09213):0.17475,CO5A2_HUMAN/41-96:0.19480):0.21928,(SOG_DROME/744-803:0.41852,(VWF_HUMAN/2257-2325:0.43363,VWF_HUMAN/2431-2494:0.54683):0.17360):0.14050):0.07295,(VWF_HUMAN/2582-2644:0.54987,(TSP1_HUMAN/318-372:0.38245,(TSP2_CHICK/326-380:0.10829,(TSP2_HUMAN/320-374:0.11154,TSP2_MOUSE/320-374:0.09030):0.11800):0.21299):0.12722):0.18333):0.10749,((SOG_DROME/941-1019:0.41250,SOG_DROME/832-898:0.48617):0.12373,SOG_DROME/102-174:0.55688):0.19121):0.25079,CEF10_CHICK/100-163:0.16105):0.14383,CTGF_HUMAN/103-166:0.13621,NOV_CHICK/106-169:0.13902);
DTP  ((((((((CO3A1_MOUSE/33-89,CO2A1_MOUSE/34-88),(CO1A1_HUMAN/40-95,CO1A1_CHICK/33-88)),CO5A2_HUMAN/41-96),(SOG_DROME/744-803,(VWF_HUMAN/2257-2325,VWF_HUMAN/2431-2494))),(VWF_HUMAN/2582-2644,(TSP1_HUMAN/318-372,(TSP2_CHICK/326-380,(TSP2_HUMAN/320-374,TSP2_MOUSE/320-374))))),((SOG_DROME/941-1019,SOG_DROME/832-898),SOG_DROME/102-174)),CEF10_CHICK/100-163),CTGF_HUMAN/103-166,NOV_CHICK/106-169);
DTL  7.76143
RID  0.369452
RPH  ((CO5A2_HUMAN/41-96:0.11128,(((TSP1_HUMAN/318-372:0.39969,(VWF_HUMAN/2582-2644:1.13966,(TSP2_CHICK/326-380:0.18879,(TSP2_HUMAN/320-374:0.04722,TSP2_MOUSE/320-374:0.06581):0.17305):0.27090):0.17610):0.46565,(VWF_HUMAN/2257-2325:1.06469,SOG_DROME/744-803:0.64611):0.04183):0.27948,(VWF_HUMAN/2431-2494:1.43311,((CEF10_CHICK/100-163:0.09012,(NOV_CHICK/106-169:0.32477,CTGF_HUMAN/103-166:0.17694):0.27406):0.32643,(SOG_DROME/102-174:0.84630,(SOG_DROME/832-898:0.91908,SOG_DROME/941-1019:0.92276):0.31786):0.62750):0.21652):0.10749):0.52414):0.37106,(CO3A1_MOUSE/33-89:0.24693,CO2A1_MOUSE/34-88:0.18379):0.00000,(CO1A1_HUMAN/40-95:0.25984,CO1A1_CHICK/33-88:0.10975):0.11480);
RTP  ((CO5A2_HUMAN/41-96,(((TSP1_HUMAN/318-372,(VWF_HUMAN/2582-2644,(TSP2_CHICK/326-380,(TSP2_HUMAN/320-374,TSP2_MOUSE/320-374)))),(VWF_HUMAN/2257-2325,SOG_DROME/744-803)),(VWF_HUMAN/2431-2494,((CEF10_CHICK/100-163,(NOV_CHICK/106-169,CTGF_HUMAN/103-166)),(SOG_DROME/102-174,(SOG_DROME/832-898,SOG_DROME/941-1019)))))),(CO3A1_MOUSE/33-89,CO2A1_MOUSE/34-88),(CO1A1_HUMAN/40-95,CO1A1_CHICK/33-88));
RTL  13.4635
LNK  CEF10_CHICK/100-163:P19336:J04496
LNK  CO1A1_CHICK/33-88:P02457:M17839
LNK  CO1A1_HUMAN/40-95:P02452:Z74615
LNK  CO2A1_MOUSE/34-88:P28481:M65161
LNK  CO3A1_MOUSE/33-89:P08121:X52046
LNK  CO5A2_HUMAN/41-96:P05997:J04478
LNK  CTGF_HUMAN/103-166:P29279:M92934
LNK  NOV_CHICK/106-169:P28686:X59284
LNK  SOG_DROME/102-174:Q24025:U18774
LNK  SOG_DROME/744-803:Q24025:U18774
LNK  SOG_DROME/832-898:Q24025:U18774
LNK  SOG_DROME/941-1019:Q24025:U18774
LNK  TSP1_HUMAN/318-372:P07996:M25631
LNK  TSP1_XENLA/321-375:P35448:
LNK  TSP2_CHICK/326-380:P35440:M60853
LNK  TSP2_HUMAN/320-374:P35442:L12350
LNK  TSP2_MOUSE/320-374:Q03350:L07803
LNK  VWF_HUMAN/2257-2325:P04275:X04385
LNK  VWF_HUMAN/2431-2494:P04275:X04385
LNK  VWF_HUMAN/2582-2644:P04275:X04385
AMK  xx.xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxx.xxxxxxxxxxxx..........xxxxxxxxxxxxxxxx
DMK  xxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
NAM  SOG_DROME/941-1019
ASQ  CK.VVNKVYENGQEWHPILMSH.GEQKCI-KCRCKD--------SKVNCDRKR..CSR--.---STCQQQTRVtskrrlfekpDAAAPAIDECCS-TQC
DSQ  TGCAAG...GTGGTCAACAAGGTGTACGAGAACGGCCAGGAGTGGCATCCGATCCTGATGTCCCAC...GGCGAGCAGAAGTGCATC---AAGTGCCGCTGCAAGGAC------------------------TCCAAGGTGAACTGCGATCGCAAGCGC......TGCTCCCGC------...---------TCCACGTGCCAGCAGCAGACACGCGTGaccagcaaacggcgtctgttcgagaaaccgGACGCAGCTGCTCCGGCCATCGATGAGTGCTGCTCC---ACCCAGTGC
TRN  11011101101011011
NAM  SOG_DROME/832-898
ASQ  CR.LGEQFHPAGASWHPFLPPN.GFDTCT-TCSCDP------LTLEIRCPRLV..CPP--.---LQCSEKL--..........-AYRPDKKACCK--IC
DSQ  TGCCGC...CTGGGCGAGCAGTTCCATCCCGCCGGTGCCAGTTGGCATCCATTCCTGCCGCCCAAT...GGCTTCGATACCTGCACC---ACCTGCAGCTGCGATCCC------------------CTGACCCTCGAGATTCGCTGTCCCCGGCTCGTC......TGCCCGCCG------...---------TTGCAGTGCAGCGAGAAGTTG------..............................---GCCTATCGTCCAGACAAGAAGGCATGCTGCAAG------ATCTGT
TRN  11011111101111111
NAM  SOG_DROME/102-174
ASQ  CQ.FGKVLRELGSTWYADLGPPfGVMYCI-KCECVAIPKKRRIVARVQCRNIKneCPP--.---AKCDDP---..........---ISLPGKCCK--TC
DSQ  TGCCAG...TTTGGCAAAGTTTTGCGCGAATTGGGGTCCACCTGGTATGCGGATTTGGGTCCACCCttcGGAGTTATGTACTGCATC---AAGTGTGAATGTGTGGCGATACCCAAGAAGCGGCGCATCGTTGCACGCGTCCAGTGTCGCAATATCAAAaacgagTGCCCGCCG------...---------GCCAAATGCGATGATCCC---------..............................---------ATCTCGTTGCCCGGAAAATGCTGCAAG------ACCTGT
TRN  10010101110011011
NAM  SOG_DROME/744-803
ASQ  CF.HSGRFYNESEQWRSAQ---.--DSCQ-MCACLR--------GQSSCEVIK..CPA--.---LKCKST---..........EQLLQRDGECCP--SC
DSQ  TGCTTT...CACTCCGGACGCTTCTACAACGAATCGGAGCAGTGGCGCAGTGCCCAG---------...------GATTCCTGTCAG---ATGTGCGCCTGTTTGCGT------------------------GGCCAATCCAGTTGCGAGGTGATCAAG......TGTCCGGCT------...---------CTCAAGTGCAAGTCCACG---------..............................GAGCAACTGCTTCAGCGTGATGGTGAATGCTGTCCC------AGCTGT
TRN  11011111101111111
NAM  TSP2_MOUSE/320-374
ASQ  CV.QEGRIFAENETWVVDS---.----CT-TCTCKK--------FKTVCHQIT..CSP--.---ATCANP---..........---SFVEGECCP--SC
DSQ  TGTGTG...CAGGAGGGCCGAATCTTTGCAGAAAATGAAACCTGGGTTGTGGATAGT---------...------------TGTACC---ACATGCACCTGCAAGAAA------------------------TTTAAAACAGTCTGCCATCAGATCACC......TGCTCACCT------...---------GCAACTTGTGCCAACCCA---------..............................---------TCTTTTGTGGAAGGCGAGTGCTGTCCA------TCCTGT
TRN  11111101111011001
NAM  TSP2_HUMAN/320-374
ASQ  CW.QDGRFFAENETWVVDS---.----CT-TCTCKK--------FKTICHQIT..CPP--.---ATCASP---..........---SFVEGECCP--SC
DSQ  TGCTGG...CAGGATGGCCGGTTCTTTGCGGAAAATGAAACGTGGGTGGTGGACAGC---------...------------TGCACC---ACGTGTACCTGCAAGAAA------------------------TTTAAAACCATTTGCCACCAAATCACC......TGCCCGCCT------...---------GCAACCTGCGCCAGTCCA---------..............................---------TCCTTTGTGGAAGGCGAATGCTGCCCT------TCCTGC
TRN  11111101111011011
NAM  TSP2_CHICK/326-380
ASQ  CW.QDGRVFADSESWIVDS---.----CT-KCTCQD--------SKIVCHQIT..CPP--.---VSCADPSF-..........-----IEGECCP--VC
DSQ  TGCTGG...CAGGATGGCCGAGTCTTTGCAGATAGTGAAAGCTGGATTGTAGATAGC---------...------------TGCACA---AAGTGCACCTGCCAGGAC------------------------TCTAAAATTGTGTGCCATCAAATCACC......TGTCCACCA------...---------GTTTCTTGTGCTGATCCGTCCTTT---..............................---------------ATTGAAGGTGAATGCTGTCCA------GTCTGC
TRN  11111101111011011
NAM  TSP1_XENLA/321-375
ASQ  CL.HNGVLHKNRDEWTVDS---.----CT-ECTCQN--------SATICRKVS..CPL--.---MPCTNA---..........---TIPDGECCP--RC
NAM  TSP1_HUMAN/318-372
ASQ  CY.HNGVQYRNNEEWTVDS---.----CT-ECHCQN--------SVTICKKVS..CPI--.---MPCSNATVP..........------DGECCP--RC
DSQ  TGCTAT...CACAACGGAGTTCAGTACAGAAATAACGAGGAATGGACTGTTGATAGC---------...------------TGCACT---GAGTGTCACTGTCAGAAC------------------------TCAGTTACCATCTGCAAAAAGGTGTCC......TGCCCCATC------...---------ATGCCCTGCTCCAATGCCACAGTTCCT..............................------------------GATGGAGAATGCTGTCCT------CGCTGT
TRN  10110101110011001
NAM  VWF_HUMAN/2582-2644
ASQ  CM.LNGTVIGPGKTVMIDV---.----CT-TCRCMVQVGVIS-GFKLECRKTT..C----.---NPCPLG---..........YKEENNTGECCG--RC
DSQ  TGCATG...CTCAATGGCACTGTCATTGGGCCCGGGAAGACTGTGATGATCGATGTG---------...------------TGCACG---ACCTGCCGCTGCATGGTGCAGGTGGGGGTCATCTCT---GGATTCAAGCTGGAGTGCAGGAAGACCACC......TGC------------...---------AACCCCTGCCCCCTGGGT---------..............................TACAAGGAAGAAAATAACACAGGTGAATGTTGTGGG------AGATGT
TRN  10010101100011011
NAM  CO5A2_HUMAN/41-96
ASQ  CT.QNGQMYLNRDIWKPAP---.----CQ-ICVCDN--------GAILCDKIE..CQDV-.---LDCADP---..........---VTPPGECCP--VC
DSQ  TGCACT...CAGAATGGCCAGATGTACTTAAACAGGGACATTTGGAAACCTGCCCCT---------...------------TGTCAG---ATCTGTGTCTGTGACAAT------------------------GGAGCCATTCTCTGTGACAAGATAGAA......TGCCAGGATGTG---...---------CTGGACTGTGCCGACCCT---------..............................---------GTAACGCCCCCTGGGGAATGCTGTCCT------GTCTGT
TRN  10010101100011010
NAM  CO2A1_MOUSE/34-88
ASQ  CL.QNGQRYKDKDVWKPSS---.----CR-ICVCDT--------GNVLCDDII..CED--.---PDCLNP---..........---EIPFGECCP--IC
DSQ  TGTCTG...CAGAATGGGCAGAGGTATAAAGATAAGGATGTATGGAAGCCCTCATCT---------...------------TGCCGC---ATCTGTGTGTGTGACACT------------------------GGGAATGTCCTCTGCGATGACATTATC......TGTGAAGAC------...---------CCAGACTGCCTCAACCCC---------..............................---------GAGATCCCCTTCGGAGAGTGCTGTCCC------ATCTGC
TRN  10010101100011001
NAM  CO1A1_CHICK/33-88
ASQ  CV.QDGLTYNDKDVWKPEP---.----CQ-ICVCDS--------GNILCDEVI..CEDT-.---SDCPNA---..........---EIPFGECCP--IC
DSQ  TGCGTC...CAGGACGGGCTGACGTACAACGATAAGGATGTGTGGAAACCCGAACCG---------...------------TGCCAG---ATCTGCGTCTGCGACAGC------------------------GGCAACATCCTCTGCGACGAGGTGATC......TGCGAGGACACC---...---------TCCGACTGCCCCAACGCC---------..............................---------GAAATCCCCTTCGGAGAGTGCTGCCCC------ATCTGC
TRN  11011101101011011
NAM  CO3A1_MOUSE/33-89
ASQ  CS.HLGQSYESRDVWKPEP---.----CQ-ICVCDS--------GSVLCDDII..CDEE-.--PLDCPNP---..........---EIPFGECCA--IC
DSQ  TGCAGC...CACCTTGGTCAGTCCTATGAGTCTAGAGATGTCTGGAAGCCAGAACCA---------...------------TGTCAA---ATATGTGTCTGTGACTCA------------------------GGATCTGTCCTTTGCGATGACATAATC......TGTGATGAGGAG---...------CCACTAGACTGCCCCAACCCA---------..............................---------GAGATCCCATTTGGAGAATGTTGTGCA------ATATGC
TRN  10010101110011001
NAM  CO1A1_HUMAN/40-95
ASQ  CV.QNGLRYHDRDVWKPEP---.----CR-ICVCDN--------GKVLCDDVI..CDET-.---KNCPGA---..........---EVPEGECCP--VC
DSQ  TGCGTA...CAGAACGGCCTCAGGTACCATGACCGAGACGTGTGGAAACCCGAGCCC---------...------------TGCCGG---ATCTGCGTCTGCGACAAC------------------------GGCAAGGTGTTGTGCGATGACGTGATC......TGTGACGAGACC---...---------AAGAACTGCCCCGGCGCC---------..............................---------GAAGTCCCCGAGGGCGAGTGCTGTCCC------GTCTGC
TRN  10010101110011011
NAM  VWF_HUMAN/2257-2325
ASQ  CIgEDGVQHQFLEAWVPDHQP-.----CQ-ICTCLS-------GRKVNCTTQP..CPTAKaPTCGLCEVA---..........-RLRQNADQCCPEYEC
DSQ  TGCATTggtGAGGATGGAGTCCAGCACCAGTTCCTGGAAGCCTGGGTCCCGGACCACCAGCCC---...------------TGTCAG---ATCTGCACATGCCTCAGC---------------------GGGCGGAAGGTCAACTGCACAACGCAGCCC......TGCCCCACGGCCAAAgctCCCACGTGTGGCCTGTGTGAAGTAGCC---------..............................---CGCCTCCGCCAGAATGCAGACCAGTGCTGCCCCGAGTATGAGTGT
TRN  11011101101011011
NAM  VWF_HUMAN/2431-2494
ASQ  CV.HRSTIYPVGQFWEEG----.----CD-VCTCTDMEDAVMGLRVAQCSQKP..CE---.---DSCRSG---..........FTYVLHEGECCG--RC
DSQ  TGTGTC...CACCGAAGCACCATCTACCCTGTGGGCCAGTTCTGGGAGGAGGGC------------...------------TGCGAT---GTGTGCACCTGCACCGACATGGAGGATGCCGTGATGGGCCTCCGCGTGGCCCAGTGCTCCCAGAAGCCC......TGTGAG---------...---------GACAGCTGTCGGTCGGGC---------..............................TTCACTTACGTTCTGCATGAAGGCGAGTGCTGTGGA------AGGTGC
TRN  10010101100011011
NAM  NOV_CHICK/106-169
ASQ  CV.FDGMIYRNGETFQPS----.----CKYQCTCRD--------GQIGCLPR-..CNLGLlLPGPDCPFPR--..........--KIEVPGECCEKWVC
DSQ  TGCGTG...TTCGATGGGATGATTTACCGCAACGGGGAGACGTTCCAGCCCAGC------------...------------TGCAAGTACCAGTGCACCTGCCGGGAC------------------------GGGCAGATCGGGTGCCTGCCCCGC---......TGCAACCTGGGCCTGctgCTCCCCGGCCCCGACTGCCCCTTCCCGCGG------..............................------AAGATCGAAGTCCCCGGAGAGTGCTGCGAGAAGTGGGTGTGC
TRN  11011111101111111
NAM  CTGF_HUMAN/103-166
ASQ  CI.FGGTVYRSGESFQSS----.----CKYQCTCLD--------GAVGCMPL-..CSMDVrLPSPDCPFPR--..........--RVKLPGKCCEEWVC
DSQ  TGCATC...TTCGGTGGTACGGTGTACCGCAGCGGAGAGTCCTTCCAGAGCAGC------------...------------TGCAAGTACCAGTGCACGTGCCTGGAC------------------------GGGGCGGTGGGCTGCATGCCCCTG---......TGCAGCATGGACGTTcgtCTGCCCAGCCCTGACTGCCCCTTCCCGAGG------..............................------AGGGTCAAGCTGCCCGGGAAATGCTGCGAGGAGTGGGTGTGT
TRN  10010101100011011
NAM  CEF10_CHICK/100-163
ASQ  CE.YNSKIYQNGESFQPN----.----CKHQCTCID--------GAVGCIPL-..CPQELsLPNLGCPSPR--..........--LVKVPGQCCEEWVC
DSQ  TGCGAA...TACAACTCCAAAATCTACCAGAACGGCGAAAGCTTCCAGCCCAAC------------...------------TGCAAGCACCAGTGTACGTGCATAGAT------------------------GGAGCTGTGGGCTGCATCCCGCTC---......TGCCCGCAGGAGCTCtccCTCCCCAACCTGGGCTGCCCCAGCCCCAGG------..............................------CTGGTCAAAGTGCCTGGGCAGTGCTGCGAGGAGTGGGTCTGC
TRN  10010101100011011
//