EMBL-EBI > Goldman Group

PANDIT Home | Browse PANDIT | Help on PANDIT | Release notes | Pfam



PANDIT Homepage
pan•dit
PANDIT
Protein and Associated NucleotideDomains with Inferred Trees
(View summary and phylogenies for PF00086 - Thyroglobulin_1)
FAM  PF00086
PID  Thyroglobulin_1
DES  Thyroglobulin type-1 repeat
IPR  IPR000716
ANO  20
ALN  84
AID  0.368343
APH  ((((THYG_HUMAN/96-160:0.10984,THYG_BOVIN/96-160:0.11780):0.49785,(THYG_BOVIN/1149-1210:0.66269,THYG_BOVIN/34-92:0.50257):0.11759):0.08599,(THYG_BOVIN/301-358:0.25088,THYG_HUMAN/301-358:0.14047):0.33088):0.28659,((TACD2_HUMAN/73-145:0.54713,TACD1_HUMAN/66-135:0.10560):1.25662,(((IBP3_BOVIN/213-285:0.33484,IBP5_HUMAN/192-263:0.28035):0.33373,IBP6_HUMAN/163-234:0.41323):0.41215,((IBP2_HUMAN/230-309:0.45016,(IBP1_HUMAN/176-251:0.21477,IBP1_BOVIN/180-255:0.17280):0.34231):0.05798,IBP4_BOVIN/174-249:0.45891):0.14129):0.34093):0.35009,((HG2A_HUMAN/213-271:0.66574,NIDO_HUMAN/849-919:0.26109):0.37180,((THYG_HUMAN/608-658:0.22915,THYG_BOVIN/607-657:0.15593):0.27443,THYG_BOVIN/661-725:0.50844):0.14718):0.17787);
ATP  ((((THYG_HUMAN/96-160,THYG_BOVIN/96-160),(THYG_BOVIN/1149-1210,THYG_BOVIN/34-92)),(THYG_BOVIN/301-358,THYG_HUMAN/301-358)),((TACD2_HUMAN/73-145,TACD1_HUMAN/66-135),(((IBP3_BOVIN/213-285,IBP5_HUMAN/192-263),IBP6_HUMAN/163-234),((IBP2_HUMAN/230-309,(IBP1_HUMAN/176-251,IBP1_BOVIN/180-255)),IBP4_BOVIN/174-249))),((HG2A_HUMAN/213-271,NIDO_HUMAN/849-919),((THYG_HUMAN/608-658,THYG_BOVIN/607-657),THYG_BOVIN/661-725)));
ATL  12.1077
DNO  19
DLN  252
DID  0.478915
DPH  ((((THYG_BOVIN/1149-1210:0.44193,(THYG_BOVIN/301-358:0.17335,THYG_HUMAN/301-358:0.11200):0.19398):0.05787,THYG_BOVIN/34-92:0.34867):0.09174,(((TACD2_HUMAN/73-145:0.34282,TACD1_HUMAN/66-135:0.32937):0.35036,(NIDO_HUMAN/849-919:0.40399,((THYG_HUMAN/608-658:0.21269,THYG_BOVIN/607-657:0.09946):0.13040,THYG_BOVIN/661-725:0.42882):0.15356):0.11744):0.12445,((((IBP1_BOVIN/180-255:0.07590,IBP1_HUMAN/176-251:0.15164):0.25845,((IBP3_BOVIN/213-285:0.21004,IBP5_HUMAN/192-263:0.31433):0.13267,IBP6_HUMAN/163-234:0.34275):0.22821):0.05547,IBP2_HUMAN/230-309:0.25060):0.08905,IBP4_BOVIN/174-249:0.22831):0.22504):0.16223):0.25086,THYG_HUMAN/96-160:0.10708,THYG_BOVIN/96-160:0.14914);
DTP  ((((THYG_BOVIN/1149-1210,(THYG_BOVIN/301-358,THYG_HUMAN/301-358)),THYG_BOVIN/34-92),(((TACD2_HUMAN/73-145,TACD1_HUMAN/66-135),(NIDO_HUMAN/849-919,((THYG_HUMAN/608-658,THYG_BOVIN/607-657),THYG_BOVIN/661-725))),((((IBP1_BOVIN/180-255,IBP1_HUMAN/176-251),((IBP3_BOVIN/213-285,IBP5_HUMAN/192-263),IBP6_HUMAN/163-234)),IBP2_HUMAN/230-309),IBP4_BOVIN/174-249))),THYG_HUMAN/96-160,THYG_BOVIN/96-160);
DTL  7.34467
RID  0.368475
RPH  ((IBP4_BOVIN/174-249:0.45200,(((IBP3_BOVIN/213-285:0.33912,IBP5_HUMAN/192-263:0.27773):0.33310,IBP6_HUMAN/163-234:0.41527):0.40042,((TACD2_HUMAN/73-145:0.54068,TACD1_HUMAN/66-135:0.11424):1.27191,((((THYG_HUMAN/608-658:0.22948,THYG_BOVIN/607-657:0.15660):0.24667,THYG_BOVIN/661-725:0.52662):0.13395,NIDO_HUMAN/849-919:0.62536):0.17549,(((THYG_HUMAN/96-160:0.10988,THYG_BOVIN/96-160:0.11862):0.49926,(THYG_BOVIN/1149-1210:0.66707,THYG_BOVIN/34-92:0.50021):0.11204):0.09209,(THYG_BOVIN/301-358:0.24460,THYG_HUMAN/301-358:0.14721):0.33006):0.28728):0.37337):0.32056):0.15534):0.06595,IBP2_HUMAN/230-309:0.45117,(IBP1_HUMAN/176-251:0.21466,IBP1_BOVIN/180-255:0.17332):0.34274);
RTP  ((IBP4_BOVIN/174-249,(((IBP3_BOVIN/213-285,IBP5_HUMAN/192-263),IBP6_HUMAN/163-234),((TACD2_HUMAN/73-145,TACD1_HUMAN/66-135),((((THYG_HUMAN/608-658,THYG_BOVIN/607-657),THYG_BOVIN/661-725),NIDO_HUMAN/849-919),(((THYG_HUMAN/96-160,THYG_BOVIN/96-160),(THYG_BOVIN/1149-1210,THYG_BOVIN/34-92)),(THYG_BOVIN/301-358,THYG_HUMAN/301-358)))))),IBP2_HUMAN/230-309,(IBP1_HUMAN/176-251,IBP1_BOVIN/180-255));
RTL  11.4441
LNK  HG2A_HUMAN/213-271:P04233:
LNK  IBP1_BOVIN/180-255:P24591:X54979
LNK  IBP1_HUMAN/176-251:P08833:Y00856
LNK  IBP2_HUMAN/230-309:P18065:S37730
LNK  IBP3_BOVIN/213-285:P20959:M76478
LNK  IBP4_BOVIN/174-249:Q05716:S52770
LNK  IBP5_HUMAN/192-263:P24593:M65062
LNK  IBP6_HUMAN/163-234:P24592:M62402
LNK  NIDO_HUMAN/849-919:P14543:M30269
LNK  TACD1_HUMAN/66-135:P16422:M32325
LNK  TACD2_HUMAN/73-145:P09758:X13425
LNK  THYG_BOVIN/1149-1210:P01267:X02815
LNK  THYG_BOVIN/301-358:P01267:X02815
LNK  THYG_BOVIN/34-92:P01267:X02815
LNK  THYG_BOVIN/607-657:P01267:X02815
LNK  THYG_BOVIN/661-725:P01267:X02815
LNK  THYG_BOVIN/96-160:P01267:X02815
LNK  THYG_HUMAN/301-358:P01266:X05615
LNK  THYG_HUMAN/608-658:P01266:U93033
LNK  THYG_HUMAN/96-160:P01266:U93033
AMK  xxxxxxxxxxxxxxxxxxxx.xx.xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
DMK  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
NAM  THYG_HUMAN/301-358
ASQ  CEVERFT-------------.--.ATSFGHPYVPSCR.RNGDYQAVQCQ-----TEGPCWCVDAQ-GKEMHGTRQQGEP--PSC
DSQ  TGTGAAGTGGAGCGGTTTACA---------------------------------------...------...GCAACCAGCTTTGGTCACCCCTATGTTCCAAGCTGCCGC...CGAAATGGCGACTATCAGGCGGTGCAGTGCCAG---------------ACGGAAGGGCCCTGCTGGTGTGTGGACGCCCAG---GGGAAGGAAATGCATGGAACCCGGCAGCAAGGGGAGCCG------CCATCTTGT
TRN  11111111111111111
NAM  THYG_BOVIN/301-358
ASQ  CEVERFA-------------.--.ATSFRHPYVPSCH.PDGEYQAAQCQ-----QGGPCWCVDSR-GQEIPGT-RQRGE-PPSC
DSQ  TGTGAAGTGGAGCGGTTTGCA---------------------------------------...------...GCCACCAGCTTCCGTCACCCCTACGTACCGAGCTGCCAC...CCGGACGGGGAGTACCAGGCGGCACAGTGCCAG---------------CAGGGAGGGCCATGCTGGTGCGTGGACAGCCGG---GGACAGGAGATCCCGGGGACG---CGGCAGCGAGGGGAG---CCTCCATCCTGT
TRN  11111111111111111
NAM  THYG_BOVIN/34-92
ASQ  CELQRER-------------.--.AFLKREDYVPQCA.EDGSFQTVQCGK----DGASCWCVDAD-GREVPGSRQPGRP--AAC
DSQ  TGTGAGCTGCAGAGGGAGAGG---------------------------------------...------...GCTTTTCTGAAGCGAGAAGACTACGTCCCCCAGTGCGCC...GAGGATGGCAGCTTCCAGACTGTCCAGTGCGGGAAG------------GATGGGGCCTCCTGCTGGTGTGTGGACGCTGAT---GGCAGGGAAGTGCCTGGTAGCCGGCAGCCCGGGCGGCCT------GCGGCCTGT
TRN  10010101100011011
NAM  THYG_BOVIN/661-725
ASQ  CEKQRARMQSLLGS------.--.QPAGSSLFVPACT.SKGNFLPVQCF------NSECYCVDTE-GQPIPGTRSALGE-PKKC
DSQ  TGCGAAAAGCAGAGGGCGCGCATGCAGAGCCTCTTGGGTAGC------------------...------...CAGCCGGCTGGGTCCAGCCTGTTTGTCCCTGCTTGTACC...AGCAAGGGGAACTTTCTCCCTGTCCAGTGCTTC------------------AACTCAGAGTGCTACTGTGTGGACACCGAG---GGTCAGCCTATTCCTGGAACTCGAAGTGCGCTTGGAGAG---CCCAAGAAATGC
TRN  10010101100011001
NAM  THYG_BOVIN/607-657
ASQ  C-------------------.--.GQAPGSLFVPACT.AEGSYEEVQCF------AGDCWCVDAQ-GRELAGSRVRGGR--PRC
DSQ  TGC---------------------------------------------------------...------...GGGCAGGCACCTGGCAGCCTTTTCGTCCCGGCATGCACT...GCGGAAGGGAGCTACGAGGAGGTCCAGTGCTTC------------------GCCGGAGACTGCTGGTGCGTGGACGCCCAG---GGCCGAGAACTTGCTGGCTCCCGGGTTAGAGGTGGACGA------CCTCGGTGC
TRN  10010101110011011
NAM  THYG_HUMAN/608-658
ASQ  C-------------------.--.EQTPERLFVPSCT.TEGSYEDVQCF------SGECWCVNSW-GKELPGSRVRGGQ--PRC
DSQ  TGT---------------------------------------------------------...------...GAGCAGACACCTGAAAGGCTATTTGTCCCATCATGCACG...ACAGAAGGAAGCTATGAGGATGTCCAATGCTTT------------------TCCGGAGAGTGCTGGTGTGTGAATTCCTGG---GGCAAAGAGCTTCCAGGCTCAAGAGTCAGAGGTGGACAG------CCAAGGTGC
TRN  10010101110011001
NAM  THYG_BOVIN/1149-1210
ASQ  CEVLQSGVP-----------.--.SRRTSPGYSPACRaEDGGFSPVQCDP----AQGSCWCVLG-SGEEVPGTRVAGSQ--PAC
DSQ  TGTGAAGTGCTCCAGAGTGGAGTCCCC---------------------------------...------...TCCAGGAGAACCAGCCCTGGCTACAGCCCGGCCTGCAGGgcaGAGGATGGAGGCTTCTCCCCAGTGCAGTGCGACCCG------------GCCCAGGGCAGCTGCTGGTGCGTCCTGGGC---AGTGGAGAGGAGGTACCCGGGACCCGCGTGGCCGGGAGCCAG------CCGGCCTGT
TRN  10010101100011011
NAM  THYG_BOVIN/96-160
ASQ  CQLQKQQILLSSY-------.--.INSTATSYLPQCQ.DSGDYSPVQCDL----RRRQCWCVDAE-GMEVYGT-RQQGR-PARC
DSQ  TGCCAGCTGCAGAAGCAGCAGATTTTGCTCAGCAGCTAC---------------------...------...ATCAACAGCACAGCCACGTCCTACCTACCCCAGTGTCAG...GATTCAGGGGATTACTCGCCCGTGCAGTGCGACCTG------------CGGCGGCGGCAGTGCTGGTGTGTGGACGCGGAA---GGAATGGAGGTGTACGGCACC---CGCCAGCAGGGGAGG---CCGGCGCGGTGT
TRN  10010101100011001
NAM  THYG_HUMAN/96-160
ASQ  CQLQKQQILLSGY-------.--.INSTDTSYLPQCQ.DSGDYAPVQCDV----QQVQCWCVDAE-GMEVYGTRQLGRP--KRC
DSQ  TGTCAGCTACAGAAACAGCAGATCTTACTGAGTGGCTAC---------------------...------...ATTAACAGCACAGACACCTCCTACCTCCCTCAGTGTCAG...GATTCAGGGGACTACGCGCCTGTTCAGTGTGATGTG------------CAGCAGGTCCAGTGCTGGTGTGTGGACGCAGAG---GGGATGGAGGTGTATGGGACCCGCCAGCTGGGGAGGCCA------AAGCGATGT
TRN  10010101100011000
NAM  NIDO_HUMAN/849-919
ASQ  CQHEREHILGAAGATDPQ--.--.RPIPPGLFVPECD.AHGHYAPTQCHG----STGYCWCVDRD-GREVEGTRTRPGMT-PPC
DSQ  TGCCAGCACGAGCGAGAACACATTCTCGGGGCAGCGGGGGCGACAGACCCACAG------...------...CGACCCATTCCTCCGGGGCTGTTCGTTCCTGAGTGCGAT...GCGCACGGGCACTACGCGCCCACCCAGTGCCACGGC------------AGCACCGGCTACTGCTGGTGCGTGGATCGCGAC---GGCCGCGAGGTGGAGGGCACCAGGACCAGGCCCGGGATGACG---CCCCCGTGT
TRN  10010101100011011
NAM  HG2A_HUMAN/213-271
ASQ  CQEEVSHI------------.--.PAVHPGSFRPKCD.ENGNYLPLQCYG----SIGYCWCVFPN-GTEVPNT-RSRGH--HNC
NAM  IBP6_HUMAN/163-234
ASQ  CRRHLDSVLQQLQTEV----.--.YRGAQTLYVPNCD.HRGFYRKRQCRSSQGQRRGPCWCVDRM-GKSLPGSPDGNGS--SSC
DSQ  TGCCGTAGACATCTGGACTCAGTGCTGCAGCAACTCCAGACTGAGGTC------------...------...TACCGAGGGGCTCAAACACTCTACGTGCCCAATTGTGAC...CATCGAGGCTTCTACCGGAAGCGGCAGTGCCGCTCCTCCCAGGGGCAGCGCCGAGGTCCCTGCTGGTGTGTGGATCGGATG---GGCAAGTCCCTGCCAGGGTCTCCAGATGGCAATGGAAGC------TCCTCCTGC
TRN  10010101100011001
NAM  IBP5_HUMAN/192-263
ASQ  CRRHMEASLQELKASP----.--.RMVPRAVYLPNCD.RKGFYKRKQCKPSRGRKRGICWCVDKY-GMKLPGMEYVDGD--FQC
DSQ  TGCCGCAGACACATGGAGGCTTCCCTGCAGGAGCTCAAAGCCAGCCCA------------...------...CGCATGGTGCCCCGTGCTGTGTACCTGCCCAATTGTGAC...CGCAAAGGATTCTACAAGAGAAAGCAGTGCAAACCTTCCCGTGGCCGCAAGCGTGGCATCTGCTGGTGCGTGGACAAGTAC---GGGATGAAGCTGCCAGGCATGGAGTACGTTGACGGGGAC------TTTCAGTGC
TRN  10010101100011011
NAM  IBP3_BOVIN/213-285
ASQ  CRREMEDTLNHLKFLN----.--.MLSPRGIHIPNCD.KKGFYKKKQCRPSKGRKRGFCWCVDKY-GQPLPGF-DVKGKGDVHC
DSQ  TGCCGCCGGGAAATGGAAGACACGCTGAACCACCTCAAGTTCCTGAAC------------...------...ATGCTCAGCCCCAGGGGCATCCACATTCCCAACTGCGAC...AAGAAGGGCTTCTACAAGAAAAAGCAGTGCCGCCCTTCCAAGGGCAGGAAGCGGGGTTTCTGCTGGTGTGTGGATAAGTAC---GGGCAGCCCCTCCCGGGCTTC---GACGTGAAGGGGAAAGGGGACGTGCACTGC
TRN  10010101100011011
NAM  IBP4_BOVIN/174-249
ASQ  CQSELHRALERLAASQSRT-.--.HEDLYIIPIPNCD.RNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGE--LDC
DSQ  TGCCAGAGTGAGCTGCACCGGGCGCTGGAGCGGCTGGCCGCCTCACAGAGCCGCACC---...------...CACGAAGACCTTTACATCATTCCCATCCCCAACTGCGAC...CGCAACGGCAACTTCCACCCCAAGCAGTGCCACCCGGCCCTGGATGGGCAGCGCGGCAAGTGCTGGTGTGTGGACCGGAAGACGGGAGTGAAGCTTCCGGGGGGCCTGGAGCCGAAGGGGGAG------CTGGACTGC
TRN  11011111101111101
NAM  IBP2_HUMAN/230-309
ASQ  CQQELDQVLERISTMRLPDErGP.LEHLYSLHIPNCD.KHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGD--PEC
DSQ  TGCCAACAGGAACTGGACCAGGTCCTGGAGCGGATCTCCACCATGCGCCTTCCGGATGAGcggGGCCCT...CTGGAGCACCTCTACTCCCTGCACATCCCCAACTGTGAC...AAGCATGGCCTGTACAACCTCAAACAGTGCAAGATGTCTCTGAACGGGCAGCGTGGGGAGTGCTGGTGTGTGAACCCCAACACCGGGAAGCTGATCCAGGGAGCCCCCACCATCCGGGGGGAC------CCCGAGTGT
TRN  11011101101011011
NAM  IBP1_HUMAN/176-251
ASQ  CRIELYRVVESLAKAQETS-.--.GEEISKFYLPNCN.KNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGD--PNC
DSQ  TGCCGAATAGAACTCTACAGAGTCGTAGAGAGTTTAGCCAAGGCACAGGAGACATCA---...------...GGAGAAGAAATTTCCAAATTTTACCTGCCAAACTGCAAC...AAGAATGGATTTTATCACAGCAGACAGTGTGAGACATCCATGGATGGAGAGGCGGGACTCTGCTGGTGCGTCTACCCTTGGAATGGGAAGAGGATCCCTGGGTCTCCAGAGATCAGGGGAGAC------CCCAACTGC
TRN  10010101100011000
NAM  IBP1_BOVIN/180-255
ASQ  CQRELYKVLDRLAREQQKA-.--.GDKLYKFYLPNCN.KNGFYHSKQCETSLEGEPGLCWCVYPWSGKRILGSVAVRGD--PKC
DSQ  TGCCAGCGAGAACTCTACAAAGTGCTGGACAGATTAGCCAGGGAGCAGCAGAAGGCA---...------...GGAGACAAACTTTACAAATTTTATCTGCCAAACTGCAAC...AAGAATGGATTCTATCACAGCAAACAGTGTGAGACGTCGCTGGAGGGAGAGCCTGGGCTCTGTTGGTGTGTCTACCCTTGGAGTGGGAAGAGGATCTTGGGGTCTGTGGCCGTCAGAGGGGAC------CCCAAATGC
TRN  10010101100011010
NAM  TACD1_HUMAN/66-135
ASQ  CLVMKAEMNGSKLGRRAKPEgA-.LQNNDGLYDPDCD.ESGLFKAKQCN-----GTSTCWCVNTA-GVRRT---DKDTE--ITC
DSQ  TGTTTGGTGATGAAGGCAGAAATGAATGGCTCAAAACTTGGGAGAAGAGCAAAACCTGAAgggGCC---...CTCCAGAACAATGATGGGCTTTATGATCCTGACTGCGAT...GAGAGCGGGCTCTTTAAGGCCAAGCAGTGCAAC---------------GGCACCTCCACGTGCTGGTGTGTGAACACTGCT---GGGGTCAGAAGAACA---------GACAAGGACACTGAA------ATAACCTGC
TRN  10010101110011001
NAM  TACD2_HUMAN/73-145
ASQ  CLLLKARMSAPKNARTLVRPsEHaLVDNDGLYDPDCD.PEGRFKARQCN-----QTSVCWCVNSV-GVRRTD--KGDLS--LRC
DSQ  TGTCTGCTGCTCAAGGCGCGCATGAGCGCCCCCAAGAACGCCCGCACGCTGGTGCGGCCGagtGAGCACgcgCTCGTGGACAACGATGGCCTCTACGACCCCGACTGCGAC...CCCGAGGGCCGCTTCAAGGCGCGCCAGTGCAAC---------------CAGACGTCGGTGTGCTGGTGCGTGAACTCGGTG---GGCGTGCGCCGCACGGAC------AAGGGCGACCTGAGC------CTACGCTGC
TRN  11011111101111111
//