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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00488 alignment
(38 sequences with 289 aa)


MSH4_CANAL/512-742 YTCPEFAK--.........---EVTIMRSLHPILGGN---.-NSNFVANNYSCNHEL.....--SRIHVITGANMSGKSVYLRQIAYLVIMAQMGCFVPAEYARMRIFNSLYSRI-SSDNVDINASSFSKEMSETAVILNDSDGDSLILIDELGRGSSLTDGFSICLAILEDLI-.CK-EATVITTTHFRDIAQVLAN.....KSC.........VV.-TAHMQTV-.........ETN.GQLEMKYNL.VLGRNDiVGYGIRFAEVSNLlPQELIEDSKVVANILRSR
MSH4_YEAST/589-818 YTIPIFTNN-.........----LLIRDSRHPLLEKVL--.--KNFVPNTISSTKHS.....--SSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARV-CNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLL-.R-TEATVFLSTHFQDIPKIMSK.....KPA.........VS.-HLHMDAV-.........LLNdNSVKMNYQLtQKSVAI.ENSGIRVVKKIFN.PD-IIAEAYNMDSLLKIA
MSH4_MOUSE/657-893 YVRPEFTD--.........---TLAIKQGWHPILEKI---.SAEKPVANNTYITEGS.....---NVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLL-.S-IKAFTLFTTHFLELCHLDAL.....YLN.........VE.-NMHFEVQHv.....kntSRNkDAILYTYKL.SRGLTEeKNYGLKAAEASSL.PSSIVLDARDITTQITRQ
MSH2_YEAST/637-882 YIRPKLHPMD.........SERRTHLISSRHPVLEMQ---.DDISFISNDVTLESGK.....--GDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIA-.SKIGCFALFATHFHELTELSEK.....LPN.........VK.-NMHVVAHIekn.lkeqkHDD.EDITLLYKV.EPGISD.QSFGIHVAEVVQF.PEKIVKMAKRKANELDDL
MSH2_HUMAN/619-854 YVRPAILEK-.........GQGRIILKASRHACVEVQ---.DEIAFIPNDVYFEKDK.....--QMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIA-.TKIGAFCMFATHFHELTALANQ.....IPT.........VN.-NLHVTAL-.........TTE.ETLTMLYQV.KKGVCD.QSFGIHVAELANF.PKHVIECAKQKALELEEF
MSH2_MAIZE/617-863 YVRPDITASD.........-EGDIVLLGSRHPCLEAQ---.DGVNFIPNDCTLVRGK.....--SWFQIITGPNMGGKSTFIRQVGVNVLMAQVGSFVPCDQASISVRDCIFARVGAGDCQLHGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLM-.EVTRAPTLFATHFHELTALAHR.....NDDehqhisdigVA.-NYHVGAHI........dPLS.RKLTMLYKV.EPGACD.QSFGIHVAEFANF.PEAVVALAKSKAAELEDF
MSH2_ARATH/616-860 YCRPEITSSD.........-AGDIVLEGSRHPCVEAQ---.DWVNFIPNDCRLMRGK.....--SWFQIVTGPNMGGKSTFIRQVGVIVLMAQVGSFVPCDKASISIRDCIFARVGAGDCQLRGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLV-.QVKRAPTLFATHFHELTALAQA.....NSEvsg..ntvgVA.-NFHVSAHI........dTES.RKLTMLYKV.EPGACD.QSFGIHVAEFANF.PESVVALAREKAAELEDF
MSH2_DROME/663-898 YVRPKMLEE-.........GARELVLEDVRHPCLELQ---.EHVNFIANSVDFKKEE.....--CNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLA-.KETKCFTLFATHFHEITKLAET.....LST.........VK.-NCHMAAV-.........ADA.DDFTLLYQV.RSGVME.KSFGIQVARLANF.PEHVVQNAQEVYNEFEDE
MUTS_BORBU/559-791 YKRPVLTSGK.........E---ILLEKSRHPVVEHYTKN.-TEIFTENFVRINKEK.....---YFCLITGPNMAGKSTYLRQVALITLMAHIGSFVPASKALIGITDKIFCRIGASDNIAKGESTFLVEMNETANILRNATEKSLIIMDEVGRGTSTNDGLAIAYSIIEYIL-.EYIKARSLFATHFHELSSINHQ.....--A.........FI.-NLSMKIE-.........KQG.NDLVFLREV.EEKPSL.NSYGIYVARIAGL.PLRVIDRANVILESLVGR
MUTS_BUCAI/570-802 YTRPIMSEKY.........G---ISLLESRHPVVECFLK-.--TPFIKNSVFLSRTQ.....---RMIIITGPNMGGKSTYMRQIALIVIMAGIGSFVPARYALIGSIDKIFTRIGSADDLSNGYSTFMMEMMEISNILHNATSNSLVLIDELGRGTSTNEGLSLAWSCSRYLI-.NINKSMTLLSTHFVELTKLEEK.....EKF.........VK.-NFHFSAI-.........KSD.LHIAFLYKI.KNGISK.KSYGISVASLSGL.PDSVLEDAEKKLIEIENT
MUTS_CHLPN/575-810 YCRPRVDMSD.........T---LCIYRGCHPVAKTLVD-.-TGKFIPNDTEMRGSQ.....--TRMILLTGPNMAGKSTYIRQIALLVIMAQMGSYIPAKSAHIGVIDKIFTRIGAGDNLSKGMSTFMVEMAETANILHNATDRSLVILDEVGRGTSTYDGLAIAQAVVEYLLFtDKKKAKTLFATHYKELTTLEDH.....CPH.........VE.-NFHAGVK-.........DKA.GQPVFLYEI.LKGHSQ.KSFGIHVARLAGF.PLCVVSRAQQILRQLEG-
MUTS_CHLMU/569-805 YRRPLVDHSD.........A---LSITKGMHPVALTLLD-.-RGTFIPNDTIMHSAQ.....--TRMILLTGPNMAGKSTYIRQIALLVIMAQMGSFIPARSAHIGIIDKIFTRIGAGDNLSKGMSTFMVEMAETANILHNATDRSLVILDEVGRGTSTYDGLAIAQAVVEFLLFtEGKKAKTLFATHYKELTELELH.....CQH.........VE.-NFHAVVK-.........ENG.GQPVFMYEI.AKGHSK.KSFGIHVAKLAGF.PLSVVSRAQQILHQFEGP
MUTS_AQUPY/561-792 WVKPEVHEGY.........E---LIIEEGKHPVIEEFTK-.---NYVPNDTKLTEEE.....---FIHVITGPNMAGKSSYIRQVGVLTLLAHTGSFLPVKSARIPLVDAIFTRIGSGDVLALGVSTFMNEMLDVSNILNNATKRSLIILDEVGRGTSTYDGIAISKAIVKYIS-.EKIGAKTLLATHYLELTELERK.....VKG.........VK.-NYHMEVE-.........ETD.EGIRFLYIL.KEGRAK.GSFGIDVAKLAGL.PEEVVREAKKILKELEGE
MUTS_AQUAE/561-792 WAKPQIHEGY.........E---LIIEEGRHPVIEEFVE-.---NYVPNDTKLDRDS.....---FIHVITGPNMAGKSSYIRQVGVLTLLSHIGSFIPARRAKIPVVDALFTRIGSGDVLALGVSTFMNEMLEVSNILNNATEKSLVILDEVGRGTSTYDGIAISKAIVKYIS-.EKLKAKTLLATHFLEITELEGK.....IEG.........VK.-NYHMEVE-.........KTP.EGIRFLYIL.KEGKAE.GSFGIEVAKLAGL.PEEVVEEARKILRELEEK
MUTS_RICPR/596-831 YTKPEFTNDL.........S---FDIVKGRHPVVEAALRK.TSKSFVYNDCHLSEAE.....---RIWLITGPNMAGKSTYLRQNAIITIIAQIGSFVPAKSAKIGVVDKIFSRIGAADDLIKGQSTFMAEMLETSAILAQSTKNSLIILDEVGRGTSTYDGVSIAWSVLEYIH-.DKLQCRCLFATHYHELTVMKNF.....LPA.........LQ.-NYTIAIE-.........ESG.KDILFLHNI.ILGASN.KSYGLHVAALAGL.PTSVINRAAQILLKFEKI
MUTS_RHIME/609-850 YTRPTVDRSR.........M---FAIDGGRHPVVEQALRRqAANPFVANGCDLSPPN...geQGGAIWLLTGPNMGGKSTFLRQNALIAIMAQTGSFVPAAAAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQATDRSLVILDEIGRGTATFDGLSIAWAAVEHLH-.EVNRCRGLFATHFHELTVLSEK.....LVR.........LS.-NATMRVK-.........EWD.GDVIFLHEV.GPGAAD.RSYGIQVARLAGL.PASVVARARDVLAKLEDA
MUTS_RHILO/605-846 WCRPVVDSSL.........A---FEISGGRHPVVEQALRRsGEGPFVANDCDLSPEG...naKNGAIWLLTGPNMGGKSTFLRQNALIAILAQTGSFVPATSAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQAGERALVILDEIGRGTATFDGLSIAWAAVEYLH-.EKNRCRAIFATHFHEMTSLAGK.....LAR.........LH.-NVTMRVK-.........EWE.GDVVFLHEV.GKGAAD.RSYGVQVARLAGL.PEAVVDRAKQVLHQLEEG
MUTS_CAUCR/601-840 AVRPVVDASY.........A---FDAKAARHPVVEAAVKR.AGEPYTPNDCRLDASG....eTAARLSIVTGPNMAGKSTFLRQNALLAILAQSGCYVPAASFRLGVVDRLFSRVGAGDDLARGRSTFMMEMVETASILTQAGPRSLVILDEIGRGTATYDGLAIAWACAEALH-.DTNRCRALFATHYHELATLETR.....MAF.........VS.-NLSLRAK-.........EWN.GDLVFLHEA.APGPAD.RSYGVQVAKLAGV.PAPVVVRAREVLDRLESK
MUTS_NEIMA/561-792 FVRPEFADYP.........A---IHIENGRHPVVEQQVR-.---HFTANHTNLDHKH.....---RLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLL-.QKNKSFSLFATHYFELTYLPEA.....HAA.........AV.-NMHLSAL-.........EQG.QDIVFLHQI.QPGPAG.KSYGIAVAKLAGL.PVRALKSAQKHLNGLENQ
MUTS_PASMU/566-798 YVAPQFSDDI.........G---VHIQQGRHPVVEQVLN-.--APFIANPVELHPQR.....---HLLIITGPNMGGKSTYMRQTALITLMAYMGSFVPAESAVIGPIDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATANSLVLIDEIGRGTSTYDGLSLAWACAEWLA-.KKLRSLTLFATHYFELTVLPEQ.....LAG.........SA.-NVHLDAI-.........EHN.DTIAFMHAV.QEGAAS.KSYGLAVAALAGV.PQSVIKLAKQKLAQLEKL
MUTS_HAEIN/569-801 YVMPTFCDEV.........S---VKIKNGRHPVVEQVLK-.--DPFIANPVELNHNR.....---HLLVITGPNMGGKSTYMRQTALITLLAYIGSFVPADSARIGPIDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATAQSLVLIDEIGRGTSTYDGLSLAWACAEWLS-.KKIRSLTLFATHYFELTALPEQ.....LEG.........IA.-NIHLDAL-.........EHN.NTIAFMHAV.QNGAAS.KSYGLAVAALAGV.PQSVIKLAKQKLTQLEKN
MUTS_SALTY/569-801 YTCPTFTDKP.........G---IRITEGRHPVVEQVLN-.--EPFIANPLNLSPQR.....---RMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLA-.NKIKALTLFATHYFELTQLPEK.....MEG.........VA.-NVHLDAL-.........EHG.DTIAFMHSV.QDGAAS.KSYGLAVAALAGV.PKEVIKRARQKLRELESI
MUTS_VIBCH/574-806 YCRPTLVQEA.........G---IHIQGGRHPVVERVMN-.--EPFIANPIELNPQR.....---RMLIITGPNMGGKSTYMRQTALIALMAHIGSYVPAESASIGPLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATRNSLVLMDEIGRGTSTYDGLSLAWASAEWLA-.KEIGAMTLFATHYFELTELPNV.....LPH.........LA.-NVHLDAV-.........EHG.DGIAFMHAV.QEGAAS.KSYGLAVAGLAGV.PKPVIKNARAKLQQLELL
MUTS_PSEAE/566-797 LNRPRFVEHT.........C---LHIEQGRHPVVEQVLE-.--TPFVANDLALDADT.....---RMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAARCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATDKSLVLMDEVGRGTSTFDGLSLAWAAAEDLA-.-RTRAFTLFATHYFELTVLPES.....QPA.........VA.-NVHLNAT-.........EHN.ERIVFLHHV.LPGPAS.QSYGLAVAQLAGV.PAPVIQRAREHLKRLETT
MUTS_XYLFA/573-810 WVRPELEHTS.........C---LHIEGGRHPVVEAV---.REQRFEPNDLDLHPER.....---RMLVITGPNMGGKSTYMRQNALIVLLAYIGSYVPASRALIGPIDRIMTRIGAGDDLARGQSTFMLEMTETSYILHHATAQSLVLMDEIGRGTSTYDGLALADAVARHLA-.HINRCYTLFATHYFELTALADEtyeggLSG.........IA.-NVHFDAV-.........EHS.ERLVFMHTV.KDGPAN.RSFGLQVAALAGL.PAAAVAHARRRLAELEQR
MUTS_TREPA/573-809 WSQPVFIKDG.........A---LRITGGRHPVVELHLP-.-SGEFVPNDLTLSSSE...haVLPRFALITGPNMAGKSTFLRQTALICLIAQVGSFVPAEKAELTPVDRIFCRVGAADNLARGESTFLVEMSETAHILRAATRDSLVIMDEVGRGTATEDGLSIAQAVSEYLL-.HHVRAKTLFATHYHELSRLAH-.....-PQ.........LE.-HLKLDVL-.........ETD.NTIVFLKKV.TPGSCG.SSYGIYVARLAGL.PESVLARACELLKQLQQR
MUTS1_HALN1/569-799 WVRPELVAGD.........G---LDIDAGRHPVVEQ----.-TTSFVPNDARFDASR.....---RFQVVTGPNMSGKSTYMRQVAVIVLLAQVGSFVPADAARIGLVDGIYTRVGALDELAGGRSTFMVEMEELSRILHAATSDSLVVLDEVGRGTATYDGISIAWAATEYLH-.NEVRATTLFATHYHELTALADH.....LDA.........VV.-NVHVAAE-.........ERD.GAVTFLRTV.RDGATD.RSYGVHVAALAGV.PEPVVDRARGVLDRLREE
MUTS2_HALN1/581-806 YTKPVMGGD-.........G---IHIEGGRHPVVERT---.-ESGFVPNDTTLNDDR.....---RVAVITGPNMSGKSTYMRQVAVIVVLAQAGCFVPAAAAELRVVDRVFTRVGASDDIAGGRSTFMVEMTELASILRAATDESLVLLDEVGRGTATTDGLAIARAVTEHIH-.DAVGATTLFATHHHELTADADR.....LPD.........AL.-NLHFAAT-.........RGD.DGVAFEHAV.RAGAAT.ASYGVEVARTAGV.PEPVVDRARELLD-----
MUTS_THEAQ/542-765 YVRPRFGD--.........R---LQIRAGRHPVVERR---.--TEFVPNDLEMAHE-.....----LVLITGPNMAGKSTFLRQTALIALLAQVGSFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEMEEVALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALH-.ER-RAYTLFATHYFELTALG--.....LPR.........LK.-NLHVAAR-.........EEA.GGLVFYHQV.LPGPAS.KSYGVEVAAMAGL.PKEVVARARALLQAMAAR
MUTS_SYNY3/604-841 YCRPIMQMEP.........G--LIDIEAGRHPVVEQSLG-.-AGFFVANDTQLGHDH.....WHPDLVILTGPNASGKSCYLRQVGLIQLMAQTGSFIPAKTATLSICDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATAKSLVLLDEIGRGTATFDGLAIAWSVAEYLA-.GEIQARTIFATHYHELNELASL.....LEN.........VA.-NFQVTVK-.........ELP.EEIIFLHQV.TPGGAD.KSYGIEAGRLAGL.PSSVITRARQVMAQIEKH
MUTS_CLOAB/565-801 YCKPVIKRDG.........T---LVIKEGRHPVVEKVIA-.-SGNFVANDTVINNSD.....--NVMMLITGPNMAGKSTYMRQVGLIVLMAQIGCFVPASAAEISICDKIFTRIGASDDLNAGKSTFMVEMWEVSHILKNATKNSLILLDEVGRGTSTYDGLSIAWSVIEYICKsENLKCKTLFATHYHELTKLEGE.....IEG.........LK.-NYSIAVK-.........KVN.DDIIFLRKI.ISKGAD.ESYGIEVAKIAGL.PEEVLVRAREILKDLEEA
MUTS_THEMA/544-769 YTKPVFSED-.........R---LEIKGGRHPVVERFT--.--QNFVENDIYMDNEK.....---RFVVITGPNMSGKSTFIRQVGLISLMAQIGSFVPAQKAILPVFDRIFTRMGARDDLAGGRSTFLVEMNEMALILLKSTNKSLVLLDEVGRGTSTQDGVSIAWAISEELI-.-KRGCKVLFATHFTELTELEKH.....FPQ.........VQ.-NKTILVK-.........EEG.KNVIFTHKV.VDGVAD.RSYGIEVAKIAGI.PDRVINRAYEILER----
MUTS_STRPY/554-787 YIRPQFNDNH.........V---ITIQEGRHAVVEKVMG-.-VQEYIPNSISFDQQT.....---SIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIH-.DRVGAKTIFATHYHELTDLSTN.....LTS.........LV.-NVHVATL-.........EKD.GDVTFLHKI.AEGPAD.KSYGIHVAKIAGL.PKSLLKRADEVLTRLETQ
MUTS_BACHD/557-790 YVRPALQEDR.........A---IAIKGGRHPVVERVIP-.-NGEYVANDVDMKDGR.....---SILLITGPNMAGKSTYMRQLALIAIMGQIGCFVPADEARLPIFDQVFTRIGAADDLASGQSTFMVEMLETKYALQKATQNSLILLDEIGRGTSTYDGMALAQAIIEYIH-.DEIRAKTLFSTHYHELTALEKE.....LSD.........VK.-NVHVSAV-.........EEQ.GTVVFLHKV.VDGQAD.RSYGIYVAELAGL.PNVVTERAETLLAELEGE
MSH1_SCHPO/696-934 FVRPVVDDSH.........A---HTVIQGRHPIVEKGLSH.KLIPFTPNDCFVGNGN.....--VNIWLITGPNMAGKSTFLRQNAIISILAQIGSFVPASNARIGIVDQIFSRIGSADNLYQQKSTFMVEMMETSFILKNATRRSFVIMDEIGRGTTASDGIAIAYGCLKYLS-.TINHSRTLFATHAHQLTNLTKS.....FKN.........VEcYCTNLSID-.........RDD.HTFSFDYKL.KKGVNY.QSHGLKVAEMAGI.PKNVLLAAEEVLTLLPNT
Q9XGD0_MAIZE/878-1125 MCRPQVLLKD.........DVPVLRMKGLWHPYAFAG---.NANSLVPNDLTLGQDL...sgLNRFALLLTGPNMGGKSTIMRATCLAVVLAQLGCYVPCTSCELTLADSIFTRLGATDRIMTGESTFLVECTETASVLQKATVDSLVLLDELGRGTSTFDGYAIAYAVFRHLV-.ERVRCRQLFATHYHSLTKEFAS.....HPH.........VS.-LQHMACMFkp....rsdGNGqKELTFLYRL.TSGACP.ESYGLQVAAMAGI.PKSIVEKASVAGQVMRAK
MSH7_ARATH/786-1048 MARPVIFPESeatdqnqktKGPILKIQGLWHPFAVAA---.DGQLPVPNDILLGEARrssgsIHPRSLLLTGPNMGGKSTLLRATCLAVIFAQLGCYVPCESCEISLVDTIFTRLGASDRIMTGESTFLVECTETASVLQNATQDSLVILDELGRGTSTFDGYAIAYSVFRHLV-.EKVQCRMLFATHYHPLTKEFAS.....HPR.........VT.-SKHMACAFksrsdyqprGCD.QDLVFLYRL.TEGACP.ESYGLQVALMAGI.PNQVVETASGAAQAMKRS
MSH6_SCHPO/974-1211 YCRPEIIEQ-.........KDGHLYFEELRHPCINASA--.-ASTFVPNDVVLGGES.....--PNMIVLTGPNMAGKSTLLRQVCIAVIMAQLGCWVPAKRASITPMTSIYTRLGANDDIMSARSTFMVELSETKKILDECGPKSLVILDELGRGTSTYDGHAIAYAVLHHLV-.SNIGCLGFFSTHYQSLCVDFMH.....HRQ.........VRlMQMAAAVD-.........EKI.RRVTFLYKL.EDGICP.KSYGMNVASMAGL.PEKVIDAAEEKASELEQA